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  • Open Access

    ARTICLE

    Multi-Time Scale Optimization Scheduling of Data Center Considering Workload Shift and Refrigeration Regulation

    Luyao Liu*, Xiao Liao, Yiqian Li, Shaofeng Zhang

    Energy Engineering, Vol.123, No.2, 2026, DOI:10.32604/ee.2025.072631 - 27 January 2026

    Abstract Data center industries have been facing huge energy challenges due to escalating power consumption and associated carbon emissions. In the context of carbon neutrality, the integration of data centers with renewable energy has become a prevailing trend. To advance the renewable energy integration in data centers, it is imperative to thoroughly explore the data centers’ operational flexibility. Computing workloads and refrigeration systems are recognized as two promising flexible resources for power regulation within data center micro-grids. This paper identifies and categorizes delay-tolerant computing workloads into three types (long-running non-interruptible, long-running interruptible, and short-running) and develops… More >

  • Open Access

    ARTICLE

    Planting Years Drive Structural and Functional Shifts in the Rhizosphere Bacterial Microbiome of Zanthoxylum bungeanum

    De Zhang1,2, Yuan-Zu Ji1, Tong Zhao1, Jun-Ying Zhao1,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.9, pp. 2815-2838, 2025, DOI:10.32604/phyton.2025.069196 - 30 September 2025

    Abstract This study investigated the effects of planting duration (1, 5, 10 and 15 years) on soil properties, bacterial community diversity, and function in the rhizosphere of Zanthoxylum bungeanum. We employed Illumina high-throughput sequencing and PICRUSt2 functional prediction to analyze the structure and functional potential of rhizosphere soil bacterial communities. The Mantel test and redundancy analysis were used to identify physicochemical factors influencing bacterial community structure and function. The results indicated significant differences in rhizosphere soil physicochemical properties across planting years: the content of organic matter, alkaline hydrolyzable nitrogen in the soil, as well as the activity… More >

  • Open Access

    ARTICLE

    Attention Shift-Invariant Cross-Evolutionary Feature Fusion Network for Infrared Small Target Detection

    Siqi Zhang, Shengda Pan*

    CMC-Computers, Materials & Continua, Vol.84, No.3, pp. 4655-4676, 2025, DOI:10.32604/cmc.2025.064864 - 30 July 2025

    Abstract Infrared images typically exhibit diverse backgrounds, each potentially containing noise and target-like interference elements. In complex backgrounds, infrared small targets are prone to be submerged by background noise due to their low pixel proportion and limited available features, leading to detection failure. To address this problem, this paper proposes an Attention Shift-Invariant Cross-Evolutionary Feature Fusion Network (ASCFNet) tailored for the detection of infrared weak and small targets. The network architecture first designs a Multidimensional Lightweight Pixel-level Attention Module (MLPA), which alleviates the issue of small-target feature suppression during deep network propagation by combining channel reshaping,… More >

  • Open Access

    REVIEW

    Hypoxic link between cancer cells and the immune system: The role of adenosine and lactate

    EDUARDO ALVARADO-ORTIZ1,2, MIGUEL ANGEL SARABIA-SáNCHEZ3,*

    Oncology Research, Vol.33, No.8, pp. 1803-1818, 2025, DOI:10.32604/or.2025.065953 - 18 July 2025

    Abstract The tumor microenvironment (TME) is characterized by a symbiosis between cancer cells and the immune cells. The scarcity of oxygen generates hostility that forces cancer cells to alter their biological features in solid tumors. In response to low oxygen availability, the Hypoxia Inducible Factors (HIF-1/2/3α) act as metabolic mediators, producing extracellular metabolites in the tumor microenvironment that influence the immune cells. The modulation of lactate and adenosine on immune evasion has been widely described; however, under hypoxic conditions, it has been barely addressed. Evidence has demonstrated an interplay between cancer and the immune cells, and More > Graphic Abstract

    Hypoxic link between cancer cells and the immune system: The role of adenosine and lactate

  • Open Access

    ARTICLE

    Cell cycle and HIF-1 related gene expression alteration in thyroid cell lines under microgravity

    JONG-HYUK AHN1, JIN WOOK YI2,3,*

    Oncology Research, Vol.33, No.8, pp. 1909-1931, 2025, DOI:10.32604/or.2025.065847 - 18 July 2025

    Abstract Background: With growing interest in space exploration, understanding microgravity’s impact on human health is essential. This study aims to investigate gene expression changes and migration and invasion potential in five thyroid-related cell lines cultured under simulated microgravity. Methods: Five thyroid-related cell lines—normal thyrocytes (Nthy-ori 3-1), papillary thyroid cancer (PTC) cells (SNU-790, TPC-1), poorly differentiated thyroid cancer cell (BCPAP), and anaplastic thyroid cancer cell (SNU-80)—were cultured under simulated microgravity (10−3 g) using a clinostat. Differentially expressed genes (DEGs) were analyzed using cDNA microarray, followed by functional annotation and assessment of aggressiveness via Transwell migration and invasion assays.… More >

  • Open Access

    ARTICLE

    OTUD7B Stabilization by METTL14-Mediated m6A Methylation Drives HIF-1α Expression in Esophageal Squamous Cell Carcinoma

    Fei Ren1,#, Yansen Cai2,#, Yang Song1,*

    Oncology Research, Vol.33, No.8, pp. 2055-2074, 2025, DOI:10.32604/or.2025.061301 - 18 July 2025

    Abstract Objectives: Epigenetic changes, particularly N6-methyladenosine (m6A) modifications, play a pivotal role in cancer development. This study explored the role of ovarian tumor deubiquitinase 7B (OTUD7B) in esophageal squamous cell carcinoma (ESCC) in the context of m6A methylation and the hypoxia-inducible factor-1α (HIF-1α) pathway. Methods: The GSE179267 dataset was used to conduct differential gene expression analysis to identify key m6A-enriched genes. The Cancer Genome Atlas (TCGA), Cancer Cell Line Encyclopedia (CCLE), and Sequence-based RNA Adenosine Methylation Site Predictor (SRAMP) databases were used to evaluate the expression of OTUD7B in ESCC and its correlation with methyltransferase-like 14… More >

  • Open Access

    ARTICLE

    Average Run Length in TEWMA Control Charts: Analytical Solutions for AR(p) Processes and Real Data Applications

    Sirawit Makaew, Yupaporn Areepong*, Saowanit Sukparungsee

    CMES-Computer Modeling in Engineering & Sciences, Vol.143, No.2, pp. 1617-1634, 2025, DOI:10.32604/cmes.2025.063459 - 30 May 2025

    Abstract This study aims to examine the explicit solution for calculating the Average Run Length (ARL) on the triple exponentially weighted moving average (TEWMA) control chart applied to autoregressive model (AR(p)), where AR(p) is an autoregressive model of order p, representing a time series with dependencies on its p previous values. Additionally, the study evaluates the accuracy of both explicit and numerical integral equation (NIE) solutions for AR(p) using the TEWMA control chart, focusing on the absolute percentage relative error. The results indicate that the explicit and approximate solutions are in close agreement. Furthermore, the study More >

  • Open Access

    ARTICLE

    UAV-Assisted Multi-Object Computing Offloading for Blockchain-Enabled Vehicle-to-Everything Systems

    Ting Chen1, Shujiao Wang2, Xin Fan3,*, Xiujuan Zhang2, Chuanwen Luo3, Yi Hong3

    CMC-Computers, Materials & Continua, Vol.81, No.3, pp. 3927-3950, 2024, DOI:10.32604/cmc.2024.056961 - 19 December 2024

    Abstract This paper investigates an unmanned aerial vehicle (UAV)-assisted multi-object offloading scheme for blockchain-enabled Vehicle-to-Everything (V2X) systems. Due to the presence of an eavesdropper (Eve), the system’s communication links may be insecure. This paper proposes deploying an intelligent reflecting surface (IRS) on the UAV to enhance the communication performance of mobile vehicles, improve system flexibility, and alleviate eavesdropping on communication links. The links for uploading task data from vehicles to a base station (BS) are protected by IRS-assisted physical layer security (PLS). Upon receiving task data, the computing resources provided by the edge computing servers (MEC)… More >

  • Open Access

    PROCEEDINGS

    Marangoni Convection Shifting, Heat Accumulation and Microstructure Evolution of Laser Directed Energy Deposition

    Donghua Dai1,2,*, Yanze Li1,2, Dongdong Gu1,2,*, Wentai Zhao1,2, Yuhang Long1,2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.4, pp. 1-1, 2024, DOI:10.32604/icces.2024.012500

    Abstract Laser Directed Energy Deposition (LDED) technology was employed to fabricate internal structures within the hollow interiors of rotating parts, such as tubes and cylinders. A three-dimensional transient multiphysics model for C276 material was developed, which anticipated the impact of angular velocity from tube rotation on various aspects. This model, validated by experiments, focused on the melt pool morphology, Marangoni convection, oriented crystal microevolution, and deposited material microhardness. It was found that at 150 ms deposition, the dimensions of the melt pool stabilized. With an increase in the Peclet number, heat transfer within the melt pool… More >

  • Open Access

    ARTICLE

    Explicitly Color-Inspired Neural Style Transfer Using Patchified AdaIN

    Bumsoo Kim1, Wonseop Shin2, Yonghoon Jung1, Youngsup Park3, Sanghyun Seo1,4,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.141, No.3, pp. 2143-2164, 2024, DOI:10.32604/cmes.2024.056079 - 31 October 2024

    Abstract Arbitrary style transfer aims to perceptually reflect the style of a reference image in artistic creations with visual aesthetics. Traditional style transfer models, particularly those using adaptive instance normalization (AdaIN) layer, rely on global statistics, which often fail to capture the spatially local color distribution, leading to outputs that lack variation despite geometric transformations. To address this, we introduce Patchified AdaIN, a color-inspired style transfer method that applies AdaIN to localized patches, utilizing local statistics to capture the spatial color distribution of the reference image. This approach enables enhanced color awareness in style transfer, adapting… More >

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