Bei Liu¹, Xian Zhang^2,*

CMES-Computer Modeling in Engineering & Sciences, Vol.130, No.3, pp. 1547-1563, 2022, DOI:10.32604/cmes.2022.018130 - 30 December 2021

Abstract During high-intensity focused ultrasound (HIFU) treatment, the accurate identification of denatured biological tissue is an important practical problem. In this paper, a novel method based on the improved variational mode decomposition (IVMD) and autoregressive (AR) model was proposed, which identified denatured biological tissue according to the characteristics of ultrasonic scattered echo signals during HIFU treatment. Firstly, the IVMD method was proposed to solve the problem that the VMD reconstruction signal still has noise due to the limited number of intrinsic mode functions (IMF). The ultrasonic scattered echo signals were reconstructed by the IVMD to achieve… More >

Jack Barkin

Canadian Journal of Urology, Vol.18, No.2, pp. 5634-5643, 2011

Abstract Introduction: Curative treatments for localized prostate cancer, from least invasive to most invasive, include brachytherapy, cryosurgery, three-dimensional conformal radiation therapy, external beam radiation therapy, and radical prostatectomy. A patient with localized, low risk or intermediate risk prostate cancer who is diagnosed at an early age and receives one of these treatments has only an approximately 50% chance of maintaining an undetectable prostate-specific antigen (PSA) level, good spontaneous erections, and total continence by 5 years after treatment.
Objective: This article discusses transrectal high intensity focused ultrasound (HIFU) treatment of localized prostate cancer using the Sonablate 500 (Focus Surgery,… More >

Dean S. Elterman^1,2, Jack Barkin^1,3, Sidney B. Radomski¹, Neil E. Fleshner¹, Brian Liu¹, Kira Bensimon¹, Samantha Arora¹, Michael Robinette¹, Antonio Finelli¹

Canadian Journal of Urology, Vol.18, No.6, pp. 6037-6042, 2011

Abstract Introduction: High-intensity focused ultrasound (HIFU) is a non-invasive technique that uses focused ultrasound waves to ablate tissue. This retrospective study evaluates the early HIFU experience at a single Canadian center.
Materials and methods: Ninety-five patients were treated between March 2006 and December 2007 using the Sonablate 500 device (Focus Surgery, Indianapolis, IN, USA). Follow-up was conducted at 3-month intervals and included serial prostate-specific antigen (PSA) measurements, assessment of erectile function using the International Index of Erectile Function (IIEF), and evaluation of continence rates using the Expanded Prostate Cancer Index Composite (EPIC) questionnaire. Early and late complications were… More >