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  • Open Access

    ARTICLE

    Blockchain-Assisted Improved Cryptographic Privacy-Preserving FL Model with Consensus Algorithm for ORAN

    Raghavendra Kulkarni1, Venkata Satya Suresh kumar Kondeti1, Binu Sudhakaran Pillai2, Surendran Rajendran3,*

    CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-23, 2026, DOI:10.32604/cmc.2025.069835 - 10 November 2025

    Abstract The next-generation RAN, known as Open Radio Access Network (ORAN), allows for several advantages, including cost-effectiveness, network flexibility, and interoperability. Now ORAN applications, utilising machine learning (ML) and artificial intelligence (AI) techniques, have become standard practice. The need for Federated Learning (FL) for ML model training in ORAN environments is heightened by the modularised structure of the ORAN architecture and the shortcomings of conventional ML techniques. However, the traditional plaintext model update sharing of FL in multi-BS contexts is susceptible to privacy violations such as deep-leakage gradient assaults and inference. Therefore, this research presents a… More >

  • Open Access

    ARTICLE

    A Privacy-Preserving Convolutional Neural Network Inference Framework for AIoT Applications

    Haoran Wang1, Shuhong Yang2, Kuan Shao2, Tao Xiao2, Zhenyong Zhang2,*

    CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-18, 2026, DOI:10.32604/cmc.2025.069404 - 10 November 2025

    Abstract With the rapid development of the Artificial Intelligence of Things (AIoT), convolutional neural networks (CNNs) have demonstrated potential and remarkable performance in AIoT applications due to their excellent performance in various inference tasks. However, the users have concerns about privacy leakage for the use of AI and the performance and efficiency of computing on resource-constrained IoT edge devices. Therefore, this paper proposes an efficient privacy-preserving CNN framework (i.e., EPPA) based on the Fully Homomorphic Encryption (FHE) scheme for AIoT application scenarios. In the plaintext domain, we verify schemes with different activation structures to determine the… More >

  • Open Access

    ARTICLE

    Numerical Analysis of Non-Uniform Pollutant Distribution in an Internal Space of Tank and the Efficacy of an Active Purification Strategy

    Xiaolong Li, Hui Chen, Yingwen Liu, Peng Yang*

    Frontiers in Heat and Mass Transfer, Vol.23, No.6, pp. 1767-1788, 2025, DOI:10.32604/fhmt.2025.070537 - 31 December 2025

    Abstract Hazardous gas intrusion in tightly sealed and geometrically complex confined spaces, such as armored tanks, poses a critical threat to occupant health. The intricate internal structure of these systems may lead to non-intuitive pollutant transport pathways. However, the spatial and temporal evolution of these structures, as well as the intrinsic mechanisms of the purification systems, remain poorly elucidated. In this study, a high-fidelity, transient three-dimensional computational fluid dynamics (CFD) model was developed to simulate the leakage and dispersion of carbon monoxide (CO) and nitrogen dioxide (NO2) using the RNG k-ε turbulence model. Scenarios with and without… More > Graphic Abstract

    Numerical Analysis of Non-Uniform Pollutant Distribution in an Internal Space of Tank and the Efficacy of an Active Purification Strategy

  • Open Access

    REVIEW

    Endothelial and Mitochondrial Dysfunction in COPD Pathophysiology: Focus on Homocysteine–L-Carnitine Interplay

    Eduard Belskikh1,*, Yuliya Marsyanova2, Denis Melnikov3, Oleg Uryasev1, Valentina Zvyagina2

    BIOCELL, Vol.49, No.11, pp. 2093-2123, 2025, DOI:10.32604/biocell.2025.069272 - 24 November 2025

    Abstract Elevated homocysteine is a clinically relevant metabolic signal in chronic obstructive pulmonary disease (COPD). Higher circulating levels track with oxidative stress, endothelial dysfunction, mitochondrial impairment, and pulmonary vascular remodeling, rise with disease severity, and may contribute to the excess cardiovascular risk—although effect sizes and causality remain uncertain. This review centers on the homocysteine–carnitine relationship in COPD pathophysiology. Carnitine deficiency, prevalent in COPD, can worsen mitochondrial bioenergetics, promote accumulation of acyl intermediates, and reduce nitric oxide bioavailability via endothelial nitric oxide synthase uncoupling (eNOS). Conversely, restoring carnitine status in experimental and early clinical settings has been… More >

  • Open Access

    PROCEEDINGS

    Stress Intensity Factor Analysis for Non-Homogeneous Materials Based on Secondary Development of ABAQUS

    Fengnan Guo1,*, Yiming Li1, Hua Zhang1, Jianwei Cui2

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.4, pp. 1-3, 2025, DOI:10.32604/icces.2025.011409

    Abstract The stress intensity factor (SIF) is one of the most crucial parameters in fracture mechanics, as it can effectively characterize the state of the crack and determine its propagation behavior. The methods for evaluating the stress intensity factor mainly include the J-integral method, interaction integral method, and displacement extrapolation method [1,2]. However, the conventional J-integral and interaction integral methods involve derivative terms of material parameters, which cause a great difficulty in applying these methods to deal with non-homogeneous materials containing material interfaces. In order to overcome this difficulty, an improved interaction integral method has been… More >

  • Open Access

    ARTICLE

    Numerical Simulation via Homotopy Perturbation Approach of a Dissipative Squeezed Carreau Fluid Flow Due to a Sensor Surface

    Sara I. Abdelsalam1,2,*, W. Abbas3, Ahmed M. Megahed4, Hassan M. H. Sadek5, M. S. Emam5

    Frontiers in Heat and Mass Transfer, Vol.23, No.5, pp. 1511-1527, 2025, DOI:10.32604/fhmt.2025.069359 - 31 October 2025

    Abstract This study rigorously examines the interplay between viscous dissipation, magnetic effects, and thermal radiation on the flow behavior of a non-Newtonian Carreau squeezed fluid passing by a sensor surface within a micro cantilever channel, aiming to deepen our understanding of heat transport processes in complex fluid dynamics scenarios. The primary objective is to elucidate how physical operational parameters influence both the velocity of fluid flow and its temperature distribution, utilizing a comprehensive numerical approach. Employing a combination of mathematical modeling techniques, including similarity transformation, this investigation transforms complex partial differential equations into more manageable ordinary… More >

  • Open Access

    ARTICLE

    Magnetohydrodynamic Jeffrey Nanofluid Flow across an Inclined Stretching Sheet via Porous Media with Slip Effects

    Pennelli Saila Kumari1, Shaik Mohammed Ibrahim1,*, Prathi Vijaya Kumar2, Giulio Lorenzini3,*

    Frontiers in Heat and Mass Transfer, Vol.23, No.5, pp. 1639-1660, 2025, DOI:10.32604/fhmt.2025.069063 - 31 October 2025

    Abstract In this paper, the authors examine various slip effects on the magnetic field and thermal radiative impacts on the flow, mass and heat transfer of a Jeffrey nanofluid over a 2-dimensional inclined stretching sheet by a porous media. The offered work is modelled to be in the form of a combination of coupled highly nonlinear partial differential equations in dimensional contexts. Governing equations were obtained, dimensionless parameters were defined in terms of similarity parameters, and the solutions were obtained by the Homotopy Analysis Method (HAM). The analysis is significant as the effects of viscosity are… More >

  • Open Access

    ARTICLE

    OCR-Assisted Masked BERT for Homoglyph Restoration towards Multiple Phishing Text Downstream Tasks

    Hanyong Lee#, Ye-Chan Park#, Jaesung Lee*

    CMC-Computers, Materials & Continua, Vol.85, No.3, pp. 4977-4993, 2025, DOI:10.32604/cmc.2025.068156 - 23 October 2025

    Abstract Restoring texts corrupted by visually perturbed homoglyph characters presents significant challenges to conventional Natural Language Processing (NLP) systems, primarily due to ambiguities arising from characters that appear visually similar yet differ semantically. Traditional text restoration methods struggle with these homoglyph perturbations due to limitations such as a lack of contextual understanding and difficulty in handling cases where one character maps to multiple candidates. To address these issues, we propose an Optical Character Recognition (OCR)-assisted masked Bidirectional Encoder Representations from Transformers (BERT) model specifically designed for homoglyph-perturbed text restoration. Our method integrates OCR preprocessing with a… More >

  • Open Access

    ARTICLE

    RAD23B Promotes Colorectal Cancer Metastasis via the Talin1/Integrin/PI3K/AKT/MMP9 Axis

    Jun Li1,#, Yang Chen1,#, Zhijiao Hao2, Zhiyong Zhang3, Jingyi Fan1, Xiao Liu1, Xueli Zhao3, Hongyan Zhang4, Chenpeng Wu3,*

    Oncology Research, Vol.33, No.11, pp. 3523-3541, 2025, DOI:10.32604/or.2025.067535 - 22 October 2025

    Abstract Background: Radiation sensitive 23 homolog B (RAD23B), a DNA repair-related protein, plays a contributory role in the development of multiple malignancies. This study aimed to explore the role of RAD23B in promoting colorectal cancer (CRC) metastasis and to elucidate the underlying molecular mechanisms. Methods: RAD23B was overexpressed in CRC cell lines SW480 and HCT-8, with empty vectors serving as controls. Invasion, cell proliferation, and migration were assessed using CCK-8 and Transwell assays. A xenograft mouse model was used to evaluate metastatic potential in vivo. Immunoprecipitation-mass spectrometry (IP-MS) and transcriptomic analysis by RNA sequencing (RNA-seq) were performed… More >

  • Open Access

    ARTICLE

    Efficacy of Wee1 G2 Checkpoint Kinase and Mouse Double Minute 2 Homolog Inhibitors in Gastrointestinal Stromal Tumors Determined by p53 Status

    Chiao-Ping Chen1,2, Yan-Jei Tang1,2, You-Yan Cai1, Yi-Ru Pan3, Chun-Nan Yeh3,4, Wen-Kuan Huang1,2, Chih-Hong Lo1,2, Yu-Tien Hsiao1,2, Hsuan-Jen Shih1,*, Chiao-En Wu1,2,4,5,*

    Oncology Research, Vol.33, No.11, pp. 3429-3446, 2025, DOI:10.32604/or.2025.066672 - 22 October 2025

    Abstract Background: KIT proto-oncogene, receptor tyrosine kinase (KIT, CD117) and platelet-derived growth factor-alpha (PDGFRA) are key drivers of gastrointestinal stromal tumors (GIST), but resistance to targeted therapy often arises from tumor protein p53 (p53) alterations and loss of cell cycle control. However, the role of p53 status in GIST therapeutic potential has rarely been studied, so this study aimed to employ both wild-type and mutant p53 GIST models to investigate how p53 dysfunction influences the efficacy of p53 pathway-targeted therapies. Methods: The efficacy of the mouse double minute 2 homolog (MDM2) inhibitor (HDM201) and the Wee1… More >

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