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    Comparison of Right Ventricle Morphological and Mechanical Characteristics for Healthy and Patients with Tetralogy of Fallot: An In Vivo MRI-Based Modeling Study

    Dalin Tang1,*,2, Heng Zuo2,*, Chun Yang2, Zheyang Wu2, Xueying Huang3, Rahul H. Rathod4, Alexander Tang4, Kristen L. Billiar5, Tal Geva4

    Molecular & Cellular Biomechanics, Vol.14, No.3, pp. 137-151, 2017, DOI:10.3970/mcb.2017.014.137

    Abstract Patients with repaired tetralogy of Fallot (TOF) account for the majority of cases with late onset right ventricle failure. Comparing TOF patients with healthy people may provide information to address this challenge. Cardiac magnetic resonance (CMR) data were obtained from 16 TOF patients (patient group, PG) and 6 healthy volunteers (healthy group, HG). At begin-of-ejection, better patient group (n=5, BPG) stress was very close to HG stress (54.7±38.4 kPa vs. 51.2±55.7 kPa, p=0.6889) while worse patient group (n=11, WPG) stress was 84% higher than HG stress (p=0.0418). Stress may be used as an indicator to differentiate More >

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