BING WANG*, KAORU TANAKA, KOUICHI MARUYAMA, YASUHARA NINOMIYA, TAKANORI KATSUBE, MITSURU NENOI*
BIOCELL, Vol.46, No.10, pp. 2315-2325, 2022, DOI:10.32604/biocell.2022.021161
Abstract Investigation on possible induction of adaptive response (AR) by high-liner energy transfer (LET) particle
radiation for protection against low-LET photon radiation-induced detrimental effects has not yet been performed in
utero. This study verified if an AR could be induced by high-LET particle radiation from accelerated heavy ions
against low-LET X-ray radiation-induced detrimental effects on fetal mice. Total body irradiation of pregnant
C57BL/6J mice were performed by delivering a priming dose ranging from 10 mGy to 320 mGy of particle radiation
on gestation day 11 followed one day later by a challenge dose at 3500 mGy from X-ray radiation. The monoenergetic… More >
Login
Register
