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    ARTICLE

    Integrated analysis of human influenza A (H1N1) virus infectionrelated genes to construct a suitable diagnostic model

    WENBIAO CHEN, KEFAN BI, JINGJING JIANG, XUJUN ZHANG, HONGYAN DIAO*

    BIOCELL, Vol.45, No.4, pp. 885-899, 2021, DOI:10.32604/biocell.2021.012938

    Abstract The genome characteristics and structural functions of coding proteins correlate with the genetic diversity of the H1N1 virus, which aids in the understanding of its underlying pathogenic mechanism. In this study, analyses of the characteristic of the H1N1 virus infection-related genes, their biological functions, and infection-related reversal drugs were performed. Additionally, we used multi-dimensional bioinformatics analysis to identify the key genes and then used these to construct a diagnostic model for the H1N1 virus infection. There was a total of 169 differently expressed genes in the samples between 21 h before infection and 77 h after infection. They were used… More >

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