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  • Open Access

    ARTICLE

    Arc Grounding Fault Identification Using Integrated Characteristics in the Power Grid

    Penghui Liu1,2,*, Yaning Zhang1, Yuxing Dai2, Yanzhou Sun1,3

    Energy Engineering, Vol.121, No.7, pp. 1883-1901, 2024, DOI:10.32604/ee.2024.049318

    Abstract Arc grounding faults occur frequently in the power grid with small resistance grounding neutral points. The existing arc fault identification technology only uses the fault line signal characteristics to set the identification index, which leads to detection failure when the arc zero-off characteristic is short. To solve this problem, this paper presents an arc fault identification method by utilizing integrated signal characteristics of both the fault line and sound lines. Firstly, the waveform characteristics of the fault line and sound lines under an arc grounding fault are studied. After that, the convex hull, gradient product,… More >

  • Open Access

    REVIEW

    Computational and bioinformatics tools for understanding disease mechanisms

    MOHD ATHAR1,*, ANU MANHAS2, NISARG RANA2, AHMAD IRFAN3

    BIOCELL, Vol.48, No.6, pp. 935-944, 2024, DOI:10.32604/biocell.2024.049891

    Abstract Computational methods have significantly transformed biomedical research, offering a comprehensive exploration of disease mechanisms and molecular protein functions. This article reviews a spectrum of computational tools and network analysis databases that play a crucial role in identifying potential interactions and signaling networks contributing to the onset of disease states. The utilization of protein/gene interaction and genetic variation databases, coupled with pathway analysis can facilitate the identification of potential drug targets. By bridging the gap between molecular-level information and disease understanding, this review contributes insights into the impactful utilization of computational methods, paving the way for More >

  • Open Access

    ARTICLE

    Influence of Methane-Hydrogen Mixture Characteristics on Compressor Vibrations

    Vladimir Ya. Modorskii, Ivan E. Cherepanov*

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.5, pp. 1031-1043, 2024, DOI:10.32604/fdmp.2024.048494

    Abstract A transition to clean hydrogen energy will not be possible until the issues related to its production, transportation, storage, etc., are adequately resolved. Currently, however, it is possible to use methane-hydrogen mixtures. Natural gas can be transported using a pipeline system with the required pressure being maintained by gas compression stations. This method, however, is affected by some problems too. Compressors emergency stops can be induced by vibrations because in some cases, mechanical methods are not able to reduce the vibration amplitude. As an example, it is known that a gas-dynamic flow effect in labyrinth… More >

  • Open Access

    ARTICLE

    Smoothed-Particle Hydrodynamics Simulation of Ship Motion and Tank Sloshing under the Effect of Regular Waves

    Mingming Zhao, Jialong Jiao*

    FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.5, pp. 1045-1061, 2024, DOI:10.32604/fdmp.2023.043744

    Abstract Predicting the response of liquefied natural gas (LNG) contained in vessels subjected to external waves is extremely important to ensure the safety of the transportation process. In this study, the coupled behavior due to ship motion and liquid tank sloshing has been simulated by the Smoothed-Particle Hydrodynamics (SPH) method. Firstly, the sloshing flow in a rectangular tank was simulated and the related loads were analyzed to verify and validate the accuracy of the present SPH solver. Then, a three-dimensional simplified LNG carrier model, including two prismatic liquid tanks and a wave tank, was introduced. Different More >

  • Open Access

    ARTICLE

    Downregulation of Calcium-Binding Protein S100A9 Inhibits Hypopharyngeal Cancer Cell Proliferation and Invasion Ability Through Inactivation of NF-κB Signaling

    Ping Wu, Huatao Quan, Jing Kang, Jian He, Shi Luo, Chubo Xie, Jing Xu, Yaoyun Tang, Suping Zhao

    Oncology Research, Vol.25, No.9, pp. 1479-1488, 2017, DOI:10.3727/096504017X14886420642823

    Abstract Hypopharyngeal cancer (HPC) frequently presents at an advanced stage and displays early submucosal spread, resulting in a poor prognosis. It is among the worst of all cancers in the head and neck subsites. Therefore, detection of HPC at an earlier stage would be beneficial to patients. In this study, we used differential in-gel electrophoresis (DIGE) and two-dimensional polyacrylamide gel electrophoresis (2-DE) proteomics analysis to identify the potential biomarkers for HPC. Among the differential proteins identified, calcium-binding protein S100A9 was overexpressed in HPC tissues compared with normal adjacent tissues, and S100A9 expression in metastatic tissues and… More >

  • Open Access

    ARTICLE

    Effects of Different Light Qualities on the Growth Characteristics of Populus trinervis

    Jiaqi Li1,2, Zhensheng Qiao1,2, Dan Zong1,2, Chengzhong He1,2,3,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.5, pp. 1043-1056, 2024, DOI:10.32604/phyton.2024.050637

    Abstract Populus trinervis is native to China and plays an irreplaceable role in maintaining the ecological balance of boreal and temperate forests. P. trinervis mainly grows in high-altitude areas. At present, there are limited studies on the response of P. trinervis to different light qualities, so it is necessary to investigate the photosynthetic physiological changes of P. trinervis in different light environments. In our study, P. trinervis was grown for 8 months under light filtered by three different colored films. The three treatments were blue film, green film, and white plastic film. The effects of blue (B), green (G), and white… More >

  • Open Access

    ARTICLE

    4-Hydroxy-2-Oxoglutaric Acid, A Key Metabolite Involved in Trypsin-Regulation of Arginine Metabolism in Hylocereus undatus during Storage

    Bairu Li1, Jingyu Jia1, Hemin Wang1, Jiaju Sun1, Enyan Chen1, Xin Li1,2,3,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.5, pp. 885-900, 2024, DOI:10.32604/phyton.2024.050450

    Abstract Trypsin, a novel superoxide scavenger, significantly enhances the storage quality of Hylocereus undatus (H. undatus). To elucidate the preservation mechanism of trypsin on H. undatus, a widely targeted metabolomic analysis, and transcriptomics analysis were conducted. Firstly, a total of 453 metabolites were identified, with organic acids and their derivatives constituting the largest proportion (25%). Amino acids and their metabolites, prominent among organic acids, were further analyzed. Among them, 73 metabolites were associated with amino acids, and 37 exhibited significant differences. The most enriched Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway was arginine biosynthesis (map00220), with polyamine metabolites… More >

  • Open Access

    REVIEW

    Research Progress on Economic Forest Water Stress Based on Bibliometrics and Knowledge Graph

    Xin Yin1,#, Shuai Wang1,#, Chunguang Wang1, Haichao Wang2, Zheying Zong1,3,*, Zeyu Ban1

    Phyton-International Journal of Experimental Botany, Vol.93, No.5, pp. 843-858, 2024, DOI:10.32604/phyton.2024.049114

    Abstract This study employed the bibliometric software CiteSpace 6.1.R6 to analyze the correlation between thermal infrared, spectral remote sensing technology, and the estimation of economic forest water stress. It aimed to review the development and current status of this field, as well as to identify future research trends. A search was conducted on the China National Knowledge Infrastructure (CNKI) database using the keyword “water stress” for relevant studies from 2003 to 2023. The visual analysis function of CNKI was used to generate the distribution of annual publication volume, and CiteSpace 6.1.R6 was utilized to create network More >

  • Open Access

    ARTICLE

    Erlotinib-Associated Rash in Advanced Non-Small Cell Lung Cancer: Relation to Clinicopathological Characteristics, Treatment Response, and Survival

    Ilias Kainis*, Nikolaos Syrigos*, Alexandra Kopitopoulou*, Ioannis Gkiozos*, Effrosyni Filiou*, Vasiliki Nikolaou*, Evangelia Papadavid

    Oncology Research, Vol.26, No.1, pp. 59-69, 2018, DOI:10.3727/096504017X14913452320194

    Abstract Systematic treatment of advanced non-small cell lung cancer (NSCLC) includes targeted treatment with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs). The development of skin rash and its intensity have been associated with EGFR TKI’s efficacy. The main purpose of this study was to further investigate the potential value of erlotinib-associated rash as a predictor of prognosis and treatment response in a real-world cohort of patients with advanced NSCLC. The medical records of all NSCLC patients treated with erlotinib at the Oncology Unit of GPP, Sotiria Athens General Hospital between January 1, 2014 and… More >

  • Open Access

    REVIEW

    MicroRNAs in thyroid cancer with focus on medullary thyroid carcinoma: potential therapeutic targets and diagnostic/prognostic markers and web based tools

    ELHAM SHAKIBA1, SETI BOROOMAND2, SIMA KHERADMAND KIA3, MEHDI HEDAYATI4,*

    Oncology Research, Vol.32, No.6, pp. 1011-1019, 2024, DOI:10.32604/or.2024.049235

    Abstract This review aimed to describe the inculpation of microRNAs (miRNAs) in thyroid cancer (TC) and its subtypes, mainly medullary thyroid carcinoma (MTC), and to outline web-based tools and databases for bioinformatics analysis of miRNAs in TC. Additionally, the capacity of miRNAs to serve as therapeutic targets and biomarkers in TC management will be discussed. This review is based on a literature search of relevant articles on the role of miRNAs in TC and its subtypes, mainly MTC. Additionally, web-based tools and databases for bioinformatics analysis of miRNAs in TC were identified and described. MiRNAs can… More > Graphic Abstract

    MicroRNAs in thyroid cancer with focus on medullary thyroid carcinoma: potential therapeutic targets and diagnostic/prognostic markers and web based tools

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