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  • Open Access

    ARTICLE

    S100B and its relation to cerebral oxygenation in neonates and infants undergoing surgery for congenital heart disease

    Jan Hinnerk Hansen1, Lydia Kissner1, Jana Logoteta1, Olaf Jung1, Peter Dütschke2, Tim Attmann3, Jens Scheewe3, Hans‐Heiner Kramer1,4

    Congenital Heart Disease, Vol.14, No.3, pp. 427-437, 2019, DOI:10.1111/chd.12741

    Abstract Objectives: Neonates and infants undergoing surgery for congenital heart disease are at risk for developmental impairment. Hypoxic‐ischemic brain injury might be one contributing factor. We aimed to investigate the perioperative release of the astro‐ cyte protein S100B and its relation to cerebral oxygenation.
    Methods: Serum S100B was measured before and 0, 12, 24, and 48 hours after sur‐ gery. Cerebral oxygen saturation was derived by near‐infrared spectroscopy. S100B reference values based on preoperative samples; concentrations above the 75th per‐ centile were defined as elevated. Patients with elevated S100B at 24 or 48 hours were compared to cases with S100B in… More >

  • Open Access

    ARTICLE

    Extreme Learning Machines Based on Least Absolute Deviation and Their Applications in Analysis Hard Rate of Licorice Seeds

    Liming Yang1,2, Junjian Bai1, Qun Sun3

    CMES-Computer Modeling in Engineering & Sciences, Vol.108, No.1, pp. 49-65, 2015, DOI:10.3970/cmes.2015.108.049

    Abstract Extreme learning machine (ELM) has demonstrated great potential in machine learning and data mining fields owing to its simplicity, rapidity and good generalization performance. In this work, a general framework for ELM regression is first investigated based on least absolute deviation (LAD) estimation (called LADELM), and then we develop two regularized LADELM formulations with the l2-norm and l1-norm regularization, respectively. Moreover, the proposed models are posed as simple linear programming or quadratic programming problems. Furthermore, the proposed models are used directly to analyze the hard rate of licorice seeds using near-infrared spectroscopy data. Experimental results on eight different spectral regions… More >

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