CHEN CAI1, HAO SUN2, LIANG HU3, ZHICHAO FAN1,*
BIOCELL, Vol.45, No.2, pp. 229-257, 2021, DOI:10.32604/biocell.2021.014338
Abstract Integrin molecules are transmembrane αβ heterodimers involved in cell adhesion, trafficking, and signaling.
Upon activation, integrins undergo dynamic conformational changes that regulate their affinity to ligands. The
physiological functions and activation mechanisms of integrins have been heavily discussed in previous studies and
reviews, but the fluorescence imaging techniques –which are powerful tools for biological studies– have not. Here we
review the fluorescence labeling methods, imaging techniques, as well as Förster resonance energy transfer assays used
to study integrin expression, localization, activation, and functions. More >
Login
Register
