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  • Open Access

    REVIEW

    Therapeutic and regenerative potential of different sources of mesenchymal stem cells for cardiovascular diseases

    YARA ALZGHOUL, HALA J. BANI ISSA, AHMAD K. SANAJLEH, TAQWA ALABDUH, FATIMAH RABABAH, MAHA AL-SHDAIFAT, EJLAL ABU-EL-RUB*, FATIMAH ALMAHASNEH, RAMADA R. KHASAWNEH, AYMAN ALZU’BI, HUTHAIFA MAGABLEH

    BIOCELL, Vol.48, No.4, pp. 559-569, 2024, DOI:10.32604/biocell.2024.048056

    Abstract Mesenchymal stem cells (MSCs) are ideal candidates for treating many cardiovascular diseases. MSCs can modify the internal cardiac microenvironment to facilitate their immunomodulatory and differentiation abilities, which are essential to restore heart function. MSCs can be easily isolated from different sources, including bone marrow, adipose tissues, umbilical cord, and dental pulp. MSCs from various sources differ in their regenerative and therapeutic abilities for cardiovascular disorders. In this review, we will summarize the therapeutic potential of each MSC source for heart diseases and highlight the possible molecular mechanisms of each source to restore cardiac function. More >

  • Open Access

    ARTICLE

    Enhanced Wolf Pack Algorithm (EWPA) and Dense-kUNet Segmentation for Arterial Calcifications in Mammograms

    Afnan M. Alhassan*

    CMC-Computers, Materials & Continua, Vol.78, No.2, pp. 2207-2223, 2024, DOI:10.32604/cmc.2024.046427

    Abstract Breast Arterial Calcification (BAC) is a mammographic decision dissimilar to cancer and commonly observed in elderly women. Thus identifying BAC could provide an expense, and be inaccurate. Recently Deep Learning (DL) methods have been introduced for automatic BAC detection and quantification with increased accuracy. Previously, classification with deep learning had reached higher efficiency, but designing the structure of DL proved to be an extremely challenging task due to overfitting models. It also is not able to capture the patterns and irregularities presented in the images. To solve the overfitting problem, an optimal feature set has been formed by Enhanced Wolf… More >

  • Open Access

    ARTICLE

    Hash Table Assisted Efficient File Level De-Duplication Scheme in SD-IoV Assisted Sensing Devices

    Ghawar Said1, Ata Ullah2, Anwar Ghani1,*, Muhammad Azeem1, Khalid Yahya3, Muhammad Bilal4, Sayed Chhattan Shah5,*

    Intelligent Automation & Soft Computing, Vol.38, No.1, pp. 83-99, 2023, DOI:10.32604/iasc.2023.036079

    Abstract The Internet of Things (IoT) and cloud technologies have encouraged massive data storage at central repositories. Software-defined networks (SDN) support the processing of data and restrict the transmission of duplicate values. It is necessary to use a data de-duplication mechanism to reduce communication costs and storage overhead. Existing State of the art schemes suffer from computational overhead due to deterministic or random tree-based tags generation which further increases as the file size grows. This paper presents an efficient file-level de-duplication scheme (EFDS) where the cost of creating tags is reduced by employing a hash table with key-value pair for each… More >

  • Open Access

    ARTICLE

    Secure and Reliable Routing in the Internet of Vehicles Network: AODV-RL with BHA Attack Defense

    Nadeem Ahmed1,*, Khalid Mohammadani2, Ali Kashif Bashir3,4,5, Marwan Omar6, Angel Jones7, Fayaz Hassan1

    CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.1, pp. 633-659, 2024, DOI:10.32604/cmes.2023.031342

    Abstract Wireless technology is transforming the future of transportation through the development of the Internet of Vehicles (IoV). However, intricate security challenges are intertwined with technological progress: Vehicular ad hoc Networks (VANETs), a core component of IoV, face security issues, particularly the Black Hole Attack (BHA). This malicious attack disrupts the seamless flow of data and threatens the network’s overall reliability; also, BHA strategically disrupts communication pathways by dropping data packets from legitimate nodes altogether. Recognizing the importance of this challenge, we have introduced a new solution called ad hoc On-Demand Distance Vector-Reputation-based mechanism Local Outlier Factor (AODV-RL). The significance of… More >

  • Open Access

    ARTICLE

    Flexible Global Aggregation and Dynamic Client Selection for Federated Learning in Internet of Vehicles

    Tariq Qayyum1, Zouheir Trabelsi1,*, Asadullah Tariq1, Muhammad Ali2, Kadhim Hayawi3, Irfan Ud Din4

    CMC-Computers, Materials & Continua, Vol.77, No.2, pp. 1739-1757, 2023, DOI:10.32604/cmc.2023.043684

    Abstract Federated Learning (FL) enables collaborative and privacy-preserving training of machine learning models within the Internet of Vehicles (IoV) realm. While FL effectively tackles privacy concerns, it also imposes significant resource requirements. In traditional FL, trained models are transmitted to a central server for global aggregation, typically in the cloud. This approach often leads to network congestion and bandwidth limitations when numerous devices communicate with the same server. The need for Flexible Global Aggregation and Dynamic Client Selection in FL for the IoV arises from the inherent characteristics of IoV environments. These include diverse and distributed data sources, varying data quality,… More >

  • Open Access

    ARTICLE

    Machine Learning-Based Decision-Making Mechanism for Risk Assessment of Cardiovascular Disease

    Cheng Wang1, Haoran Zhu2,*, Congjun Rao2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.138, No.1, pp. 691-718, 2024, DOI:10.32604/cmes.2023.029258

    Abstract Cardiovascular disease (CVD) has gradually become one of the main causes of harm to the life and health of residents. Exploring the influencing factors and risk assessment methods of CVD has become a general trend. In this paper, a machine learning-based decision-making mechanism for risk assessment of CVD is designed. In this mechanism, the logistics regression analysis method and factor analysis model are used to select age, obesity degree, blood pressure, blood fat, blood sugar, smoking status, drinking status, and exercise status as the main pathogenic factors of CVD, and an index system of risk assessment for CVD is established.… More >

  • Open Access

    ARTICLE

    Multi Head Deep Neural Network Prediction Methodology for High-Risk Cardiovascular Disease on Diabetes Mellitus

    B. Ramesh, Kuruva Lakshmanna*

    CMES-Computer Modeling in Engineering & Sciences, Vol.137, No.3, pp. 2513-2528, 2023, DOI:10.32604/cmes.2023.028944

    Abstract Major chronic diseases such as Cardiovascular Disease (CVD), diabetes, and cancer impose a significant burden on people and healthcare systems around the globe. Recently, Deep Learning (DL) has shown great potential for the development of intelligent mobile Health (mHealth) interventions for chronic diseases that could revolutionize the delivery of health care anytime, anywhere. The aim of this study is to present a systematic review of studies that have used DL based on mHealth data for the diagnosis, prognosis, management, and treatment of major chronic diseases and advance our understanding of the progress made in this rapidly developing field. Type 2… More > Graphic Abstract

    Multi Head Deep Neural Network Prediction Methodology for High-Risk Cardiovascular Disease on Diabetes Mellitus

  • Open Access

    ARTICLE

    Decision Analysis on IoV Routing Transmission and Energy Efficiency Optimization Algorithm with AmBC

    Baofeng Ji1,2,3,*, Mingkun Zhang1,2, Weixing Wang1, Song Chen4

    CMES-Computer Modeling in Engineering & Sciences, Vol.137, No.3, pp. 2661-2673, 2023, DOI:10.32604/cmes.2023.028762

    Abstract The improvement of the quality and efficiency of vehicle wireless network data transmission is always a key concern in the Internet of Vehicles (IoV). Routing transmission solved the limitation of transmission distance to a certain extent. Traditional routing algorithm cannot adapt to complex traffic environment, resulting in low transmission efficiency. In order to improve the transmission success rate and quality of vehicle network routing transmission, make the routing algorithm more suitable for complex traffic environment, and reduce transmission power consumption to improve energy efficiency, a comprehensive optimized routing transmission algorithm is proposed. Based on the routing transmission algorithm, an optimization… More >

  • Open Access

    ARTICLE

    Deep Learning Approach for Automatic Cardiovascular Disease Prediction Employing ECG Signals

    Muhammad Tayyeb1, Muhammad Umer1, Khaled Alnowaiser2, Saima Sadiq3, Ala’ Abdulmajid Eshmawi4, Rizwan Majeed5, Abdullah Mohamed6, Houbing Song7, Imran Ashraf8,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.137, No.2, pp. 1677-1694, 2023, DOI:10.32604/cmes.2023.026535

    Abstract Cardiovascular problems have become the predominant cause of death worldwide and a rise in the number of patients has been observed lately. Currently, electrocardiogram (ECG) data is analyzed by medical experts to determine the cardiac abnormality, which is time-consuming. In addition, the diagnosis requires experienced medical experts and is error-prone. However, automated identification of cardiovascular disease using ECGs is a challenging problem and state-of-the-art performance has been attained by complex deep learning architectures. This study proposes a simple multilayer perceptron (MLP) model for heart disease prediction to reduce computational complexity. ECG dataset containing averaged signals with window size 10 is… More >

  • Open Access

    REVIEW

    The role of periodontal disease in atherosclerotic cardiovascular disease

    XIWEI ZHAO1,#, JINSONG WANG1,2,#, YIFAN XU1, JIAN ZHOU5,*, LEI HU1,3,4,*

    BIOCELL, Vol.47, No.7, pp. 1431-1438, 2023, DOI:10.32604/biocell.2023.028217

    Abstract Atherosclerotic cardiovascular disease (ASCVD) includes a group of disorders of the heart and blood vessels and accounts for major morbidity and premature death worldwide. Periodontitis is a chronic inflammatory disease with the gradual destruction of supporting tissues around the teeth, including gingiva, periodontal ligament, alveolar bone, and cementum. Periodontitis has been found to potentially increase the risk of ASCVD. Generally, oral microorganisms and inflammation are the major factors for periodontitis to the incidence of ASCVD. Recently, evidence has shown that the loss of masticatory function is another important factor of periodontitis to the incidence of ASCVD. In this review, we… More > Graphic Abstract

    The role of periodontal disease in atherosclerotic cardiovascular disease

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