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Therapeutic and regenerative potential of different sources of mesenchymal stem cells for cardiovascular diseases

YARA ALZGHOUL, HALA J. BANI ISSA, AHMAD K. SANAJLEH, TAQWA ALABDUH, FATIMAH RABABAH, MAHA AL-SHDAIFAT, EJLAL ABU-EL-RUB*, FATIMAH ALMAHASNEH, RAMADA R. KHASAWNEH, AYMAN ALZU’BI, HUTHAIFA MAGABLEH

Department of Basic Medical Sciences, Faculty of Medicine, Yarmouk University, Irbid, Jordan

* Corresponding Author: EJLAL ABU-EL-RUB. Email: email

(This article belongs to the Special Issue: Perspectives on Stem Cells and Regenerative Medicine)

BIOCELL 2024, 48(4), 559-569. https://doi.org/10.32604/biocell.2024.048056

Abstract

Mesenchymal stem cells (MSCs) are ideal candidates for treating many cardiovascular diseases. MSCs can modify the internal cardiac microenvironment to facilitate their immunomodulatory and differentiation abilities, which are essential to restore heart function. MSCs can be easily isolated from different sources, including bone marrow, adipose tissues, umbilical cord, and dental pulp. MSCs from various sources differ in their regenerative and therapeutic abilities for cardiovascular disorders. In this review, we will summarize the therapeutic potential of each MSC source for heart diseases and highlight the possible molecular mechanisms of each source to restore cardiac function.

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APA Style
ALZGHOUL, Y., ISSA, H.J.B., SANAJLEH, A.K., ALABDUH, T., RABABAH, F. et al. (2024). Therapeutic and regenerative potential of different sources of mesenchymal stem cells for cardiovascular diseases. BIOCELL, 48(4), 559-569. https://doi.org/10.32604/biocell.2024.048056
Vancouver Style
ALZGHOUL Y, ISSA HJB, SANAJLEH AK, ALABDUH T, RABABAH F, AL-SHDAIFAT M, et al. Therapeutic and regenerative potential of different sources of mesenchymal stem cells for cardiovascular diseases. BIOCELL . 2024;48(4):559-569 https://doi.org/10.32604/biocell.2024.048056
IEEE Style
Y. ALZGHOUL et al., "Therapeutic and regenerative potential of different sources of mesenchymal stem cells for cardiovascular diseases," BIOCELL , vol. 48, no. 4, pp. 559-569. 2024. https://doi.org/10.32604/biocell.2024.048056



cc This work is licensed under a Creative Commons Attribution 4.0 International License , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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