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    ARTICLE

    Fluid-Structure Interaction Simulation of Aqueous Outflow System in Response to Juxtacanalicular Meshwork Permeability Changes with a Two-Way Coupled Method

    Jing Zhang1,2,3, Xiuqing Qian1,2, Haixia Zhang1,2, Zhicheng Liu1,2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.116, No.2, pp. 301-314, 2018, DOI: 10.31614/cmes.2018.04239

    Abstract Elevated intraocular pressure appears to have a broader impact on increased resistance to aqueous humor outflow through the conventional aqueous outflow system (AOS). However, there is still no consensus about exact location of the increased outflow resistance of aqueous humor, and the mechanism is not perfect. In addition, it is difficult to accurately obtain hydrodynamic parameters of aqueous humor within the trabecular meshwork outflow pathways based on the current technology. In this paper, a two-way fluid-structure interaction simulation was performed to study the pressure difference and velocity in the superficial trabecular meshwork, juxtacanalicular meshwork (JCM) and Schlemm’s canal in response… More >

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