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  • Open Access

    ARTICLE

    Identification of Single Nucleotide Polymorphisms and Analysis of Linkage Disequilibrium in Different Bamboo Species Using the Candidate Gene Approach

    Xihua Liu1, Min Luo1, Xiaofei Chen1, Changjun Ding2,*

    Phyton-International Journal of Experimental Botany, Vol.90, No.6, pp. 1697-1709, 2021, DOI:10.32604/phyton.2021.015295

    Abstract Bamboos are one of the most beautiful and useful plants on Earth. The genetic background and population structure of bamboos are well known, which helps accelerate the process of artificial domestication of bamboo. Partial sequences of six genes involved in nitrogen use efficiency in 32 different bamboo species were analyzed for occurrence of single nucleotide polymorphisms (SNPs). The nucleotide diversity θw and total nucleotide polymorphisms πT of the sequenced DNA regions was 0.05137 and 0.03332, respectively. Both πnonsyn /πsyn and Ka/Ks values were <1. The nucleotide sequences of these six genes were inferred to be relatively conserved, and the haplotype… More >

  • Open Access

    ARTICLE

    Parameter Estimation of Alpha Power Inverted Topp-Leone Distribution with Applications

    Gamal M. Ibrahim1, Amal S. Hassan2, Ehab M. Almetwally3,*, Hisham M. Almongy4

    Intelligent Automation & Soft Computing, Vol.29, No.2, pp. 353-371, 2021, DOI:10.32604/iasc.2021.017586

    Abstract We introduce a new two-parameter lifetime model, referred to alpha power transformed inverted Topp-Leone, derived by combining the alpha power transformation-G family with the inverted Topp-Leone distribution. Structural properties of the proposed distribution are implemented like; quantile function, residual and reversed residual life, Rényi entropy measure, moments and incomplete moments. The maximum likelihood, weighted least squares, maximum product of spacing, and Bayesian methods of estimation are considered. A simulation study is worked out to evaluate the restricted sample properties of the proposed distribution. Numerical results showed that the Bayesian estimates give more accurate results than the corresponding other estimates in… More >

  • Open Access

    ARTICLE

    Kumaraswamy Inverted Topp–Leone Distribution with Applications to COVID-19 Data

    Amal S. Hassan1, Ehab M. Almetwally2,*, Gamal M. Ibrahim3

    CMC-Computers, Materials & Continua, Vol.68, No.1, pp. 337-358, 2021, DOI:10.32604/cmc.2021.013971

    Abstract In this paper, an attempt is made to discover the distribution of COVID-19 spread in different countries such as; Saudi Arabia, Italy, Argentina and Angola by specifying an optimal statistical distribution for analyzing the mortality rate of COVID-19. A new generalization of the recently inverted Topp Leone distribution, called Kumaraswamy inverted Topp–Leone distribution, is proposed by combining the Kumaraswamy-G family and the inverted Topp–Leone distribution. We initially provide a linear representation of its density function. We give some of its structure properties, such as quantile function, median, moments, incomplete moments, Lorenz and Bonferroni curves, entropies measures and stress-strength reliability. Then,… More >

  • Open Access

    ARTICLE

    Synergetic effects of shock waves with polydeoxyribonucleotides on rotator cuff tendon tear in a rabbit model

    DONG HAN KIM1, DONG RAK KWON1,*, GI-YOUNG PARK1, YONG SUK MOON2

    BIOCELL, Vol.45, No.3, pp. 527-536, 2021, DOI:10.32604/biocell.2021.014350

    Abstract This work aimed to investigate the synergetic therapeutic effects of polydeoxyribonucleotides (PDRN) combined with extracorporeal shock waves therapy (ESWT) and the effects of the therapy according to ESWT sequences on a chronic traumatic full-thickness rotator cuff tear (RCT) in rabbit models. For this purpose, thirty-two rabbits were randomly allocated into 4 groups. An excision was made to create a 5-mm sized full-thickness RCT right proximal to the insertion site on the supraspinatus. After 6 weeks, 4 different procedures (normal saline, Group 1; PDRN injection, Group 2; PDRN injection before ESWT, Group 3; PDRN injection after ESWT, Group 4) were performed.… More >

  • Open Access

    ARTICLE

    Newly identified genetic variant rs2294693 in UNC5CL gene is associated with decreased risk of esophageal carcinoma in the J&K Population–India

    RUCHI SHAH1,*, SONALI VERMA1, AMRITA BHAT1, GH RASOOL BHAT1, VARUN SHARMA1, INDU SHARMA1, HEMENDER SINGH1, SANDEEP KAUL2, EKTA RAI1, SWARKAR SHARMA1,*

    BIOCELL, Vol.45, No.3, pp. 665-670, 2021, DOI:10.32604/biocell.2021.09629

    Abstract Esophageal cancer is the second most common type of cancer after lung carcinoma in the state of Jammu and Kashmir (J&K). The understanding of genetics in Esophageal cancer development is poor in the state. Genome wide association studies (GWAS) has proved to be unsurpassed tool in identification of new loci associated with different cancers. GWAS in Chinese population has identified SNP rs2294693 present in UNC5CL (UNC-5 Family C-Terminal like) to be associated with non-cardia gastric cancer. We performed a case control association study and genotyped the SNP rs2294693 using Taqman allele discrimination assay in 566 individuals (166 esophageal cancer patients… More >

  • Open Access

    ARTICLE

    CLEC3A gene three polymorphisms and risk of gastric cancer in Northwestern Chinese population

    PING YANG, LIJUAN YUAN, SHUJIA PENG, YANMING DONG, LIN YANG, XI’E HU, GUOQIANG BAO*

    BIOCELL, Vol.45, No.1, pp. 103-108, 2021, DOI:10.32604/biocell.2021.011220

    Abstract This study aimed to evaluate the association between the CLEC3A gene polymorphisms (rs2735401/rs2293776/ rs2072665) and the gastric cancer risk in the Northwestern Chinese population. A hospital-based case-control study was conducted on 681 cases and 756 healthy controls. Odds ratio (OR) and 95% confidence intervals (CI) were applied to evaluate the association of the CLEC3A polymorphisms on gastric cancer risk. We found that there was no significant association between the CLEC3A polymorphisms and gastric cancer susceptibility, which was detected in the main analysis or stratification analyses of age, gender, and clinical stages. Our findings verified that the CLEC3A polymorphisms are not… More >

  • Open Access

    ARTICLE

    Power Inverted Topp–Leone Distribution in Acceptance Sampling Plans

    Tahani A. Abushal1, Amal S. Hassan2, Ahmed R. El-Saeed3, Said G. Nassr4,*

    CMC-Computers, Materials & Continua, Vol.67, No.1, pp. 991-1011, 2021, DOI:10.32604/cmc.2021.014620

    Abstract We introduce a new two-parameter model related to the inverted Topp–Leone distribution called the power inverted Topp–Leone (PITL) distribution. Major properties of the PITL distribution are stated; including; quantile measures, moments, moment generating function, probability weighted moments, Bonferroni and Lorenz curve, stochastic ordering, incomplete moments, residual life function, and entropy measure. Acceptance sampling plans are developed for the PITL distribution, when the life test is truncated at a pre-specified time. The truncation time is assumed to be the median lifetime of the PITL distribution with pre-specified factors. The minimum sample size necessary to ensure the specified life test is obtained… More >

  • Open Access

    ARTICLE

    Research into Visual Servo Based Haptic Feedback Teleoperation

    Tao Ni1, Lingtao Huang1,*, Huanfei Zheng2, Hongyan Zhang1

    Intelligent Automation & Soft Computing, Vol.27, No.1, pp. 143-158, 2021, DOI:10.32604/iasc.2021.012268

    Abstract To overcome the problem that a teleoperation system loses robustness when the target moves outside the robot’s visual field or it is far away from the desired position, and to improve the operability and controllability of a master-slave teleoperation system, we present an image servo based haptic feedback (ISBHF) control method for teleoperating. The ISBHF control method involves extracting target feature points and constructing image servo based virtual force. First, the image characteristics of the environment and targets are identified and extracted by a 3D reconstruction method. A composite image Jacobian matrix is used to construct virtual guidance force based… More >

  • Open Access

    ARTICLE

    Two polymorphisms in methylenetetrahydrofolate reductase gene (C677T and A1298C) frequently associated with recurrent spontaneous abortion show no association in Saudi women

    AFRAH ALKHURIJI1, ATEKAH ABDULLAH MOHAMMED ALRAQIBAH1, AMAAL AWAD ALHARBI1, ZENEB BABAY2, FATIMAH BASIL AL-MUKAYNIZI3, ARWA ALTHOMALI3, SONYA S. ABDEL-RAZEQ4, ARJUMAND S. WARSY5

    BIOCELL, Vol.44, No.4, pp. 613-621, 2020, DOI:10.32604/biocell.2020.09652

    Abstract Methylenetetrahydrofolate reductase (MTHFR) deficiency is the most common genetic cause of hyperhomocysteinemia, which has been implicated in the etiology of recurrent spontaneous abortion (RSA). This study was designed to investigate the association between two single nucleotide polymorphisms (SNP) (rs1801133 [C677T] and rs1801131 [A1298C]) in the MTHFR gene and RSA, in Saudis. These two SNPs were selected as these polymorphisms have a different effect on the activity and stability of the enzyme, and significantly diverse effects have been reported in relation to the association with RSA. Ethical approval was acquired from the IRB at King Saud University (KKUH), Saudi Arabia, and… More >

  • Open Access

    ARTICLE

    Topp-Leone Odd Fréchet Generated Family of Distributions with Applications to COVID-19 Data Sets

    Sanaa Al-Marzouki1, Farrukh Jamal2, Christophe Chesneau3,*, Mohammed Elgarhy4

    CMES-Computer Modeling in Engineering & Sciences, Vol.125, No.1, pp. 437-458, 2020, DOI:10.32604/cmes.2020.011521

    Abstract Recent studies have pointed out the potential of the odd Fréchet family (or class) of continuous distributions in fitting data of all kinds. In this article, we propose an extension of this family through the so-called “Topp-Leone strategy”, aiming to improve its overall flexibility by adding a shape parameter. The main objective is to offer original distributions with modifiable properties, from which adaptive and pliant statistical models can be derived. For the new family, these aspects are illustrated by the means of comprehensive mathematical and numerical results. In particular, we emphasize a special distribution with three parameters based on the… More >

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