Home / Advanced Search

  • Title/Keywords

  • Author/Affliations

  • Journal

  • Article Type

  • Start Year

  • End Year

Update SearchingClear
  • Articles
  • Online
Search Results (1)
  • Open Access


    miR-122 Inhibits Hepatocarcinoma Cell Progression by Targeting LMNB2

    Xiao-Na L*i, Hong Yang, Tao Yang

    Oncology Research, Vol.28, No.1, pp. 41-49, 2020, DOI:10.3727/096504019X15615433287579

    Abstract In the present study, we investigated the role of miR-122 in hepatocarcinoma progression and explored the mechanism. In hepatocarcinoma tissues and cells, we used qRT-PCR to validate the miR-122 expression level. Next, we used colony formation by crystal violet staining assay to compare cell proliferation ability, and we used scratch test or Transwell assay to compare cell migration or invasion ability. We then conducted bioinformatics or luciferase reporter gene assay to prove the regulation effect of miR-122 on lamin B2 (LMNB2), and the biological function of LMNB2 was analyzed. We used nude mouse tumorigenicity assay to test the inhibition effect… More >

Displaying 1-10 on page 1 of 1. Per Page