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  • Open Access

    ARTICLE

    Wheat Leaf Rust Detection and Infected-Area Estimation Using Multi-Scale Fusion and Lab-Based Lesion Localization

    Sajid Ullah Khan*

    CMC-Computers, Materials & Continua, Vol.88, No.1, 2026, DOI:10.32604/cmc.2026.079440 - 08 May 2026

    Abstract Healthcare, education, technological advancement, and farming are the key challenges facing developing countries, with agriculture unquestionably playing an important role in economic growth. Ensuring adequate food production is essential for citizens’ survival, as it is anticipated that efforts in this area would result in increased food productivity. A key approach to enhancing field productivity involves meticulous care of its components, starting with the production of crops. Wheat leaf rust poses a severe threat, particularly to young seedlings, constituting a significant fungal disease that can cause a 25% reduction in wheat productivity. To overcome these issues,… More >

  • Open Access

    ARTICLE

    Multimodal Graph-Enhanced Vision Transformer for Interpretable Skin Lesion Classification

    Faten S. Alamri1, Noor Ayesha2, Afia Zafar3, Adil Ali Saleem4,*, Amjad R. Khan5

    CMES-Computer Modeling in Engineering & Sciences, Vol.147, No.1, 2026, DOI:10.32604/cmes.2026.080335 - 27 April 2026

    Abstract The use of automated skin lesion classification is still a disadvantage, since there is a great visual similarity between benign and malignant lesions. The majority of deep learning methods utilize dermoscopic images only, without taking into account clinical metadata employed by dermatologists on a regular basis. The following paper proposes a vision-graph multimodal framework that links Image encoding to graph neural networks based on metadata representation through the fusion of learnable attention. The framework focuses on three limitations, which are underutilization of clinical context, absence of interpretability, and suboptimal incorporation of modalities. Gradient-weighted Class Activation… More > Graphic Abstract

    Multimodal Graph-Enhanced Vision Transformer for Interpretable Skin Lesion Classification

  • Open Access

    ARTICLE

    Association of tertiary lymphoid structures and benign lymphoepithelial lesions in NIH-category IV prostatitis: pathophysiological correlations

    Dorian Dikov1, Maria Koleva2,*, Kiril Simitchiev3, Anelia Bivolarska4, Albena Fakirova5, Victoria Sarafian6,7

    Canadian Journal of Urology, Vol.33, No.1, pp. 125-134, 2026, DOI:10.32604/cju.2025.068575 - 28 February 2026

    Abstract Background: Chronic inflammation is closely associated with the most common and socially significant prostate conditions, including benign prostatic hyperplasia (BPH), prostate cancer (PCa), and prostatitis syndromes. NIH-category IV prostatitis (histologic prostatitis, HP) is defined as asymptomatic chronic inflammation of the prostate. The presence of lymphoid follicles, referred to as tertiary lymphoid structures (TLSs), along with benign lympho-epithelial lesions (BLELs), is among the key histological indicators of immune inflammation and can be assessed relatively easily. This study aimed to quantitatively assess TLSs and BLELs, as well as their relationship with the severity of HP. Methods: We… More >

  • Open Access

    ARTICLE

    Graph Attention Networks for Skin Lesion Classification with CNN-Driven Node Features

    Ghadah Naif Alwakid1, Samabia Tehsin2,*, Mamoona Humayun3,*, Asad Farooq2, Ibrahim Alrashdi1, Amjad Alsirhani1

    CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-21, 2026, DOI:10.32604/cmc.2025.069162 - 10 November 2025

    Abstract Skin diseases affect millions worldwide. Early detection is key to preventing disfigurement, lifelong disability, or death. Dermoscopic images acquired in primary-care settings show high intra-class visual similarity and severe class imbalance, and occasional imaging artifacts can create ambiguity for state-of-the-art convolutional neural networks (CNNs). We frame skin lesion recognition as graph-based reasoning and, to ensure fair evaluation and avoid data leakage, adopt a strict lesion-level partitioning strategy. Each image is first over-segmented using SLIC (Simple Linear Iterative Clustering) to produce perceptually homogeneous superpixels. These superpixels form the nodes of a region-adjacency graph whose edges encode… More >

  • Open Access

    ARTICLE

    Astilbin ameliorates propranolol-induced psoriasis-like lesions through restoring Th17/Treg immune homeostasis in lymph nodes

    Yayun Wu1,2,3,#, Qi Xia1,#, Dancai Fan1, Ya Zhao1,3, Lijuan Liu1,3, Shigui Deng1,3, Ruizhi Zhao1,2,3

    European Cytokine Network, Vol.36, No.3, pp. 52-63, 2025, DOI:10.1684/ecn.2025.0505 - 28 February 2026

    Abstract Background: Psoriasis is a challenging immune-mediated dermatological disorder with an urgent need for effective clinical therapeutics, while astilbin has shown considerable efficacy in suppressing psoriasis progression, its underlying mechanisms are not fully clarified. This study aimed to systematically investigate the anti-psoriatic effects of astilbin and to elucidate its potential mechanisms of action. Methods: A psoriasis-like mouse model was established via cold water swimming, dietary restriction, and topical application of 5% propranolol emulsion, followed by daily treatment with low- (25.6 mg/kg), middle- (51.2 mg/kg), or high-dose (76.8 mg/kg) astilbin for 6 consecutive days, with evaluations including… More >

  • Open Access

    EDITORIAL

    Current practices and future directions in prostate biopsy techniques: insights from a meta-analysis and european multicenter survey

    Xingkang Jiang*, Jing Tian, Yong Xu

    Canadian Journal of Urology, Vol.32, No.6, pp. 539-540, 2025, DOI:10.32604/cju.2025.073363 - 30 December 2025

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Advancing Radiological Dermatology with an Optimized Ensemble Deep Learning Model for Skin Lesion Classification

    Adeel Akram1, Tallha Akram2, Ghada Atteia3,*, Ayman Qahmash4, Sultan Alanazi5, Faisal Mohammad Alotaibi5

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.2, pp. 2311-2337, 2025, DOI:10.32604/cmes.2025.069697 - 26 November 2025

    Abstract Advancements in radiation-based imaging and computational intelligence have significantly improved medical diagnostics, particularly in dermatology. This study presents an ensemble-based skin lesion classification framework that integrates deep neural networks (DNNs) with transfer learning, a customized DNN, and an optimized self-learning binary differential evolution (SLBDE) algorithm for feature selection and fusion. Leveraging computational techniques alongside medical imaging modalities, the proposed framework extracts and fuses discriminative features from multiple pre-trained models to improve classification robustness. The methodology is evaluated on benchmark datasets, including ISIC 2017 and the Argentina Skin Lesion dataset, demonstrating superior accuracy, precision, and F1-score… More >

  • Open Access

    ARTICLE

    HybridFusionNet with Explanability: A Novel Explainable Deep Learning-Based Hybrid Framework for Enhanced Skin Lesion Classification Using Dermoscopic Images

    Mohamed Hammad1,2,*, Mohammed ElAffendi1, Souham Meshoul3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.1, pp. 1055-1086, 2025, DOI:10.32604/cmes.2025.072650 - 30 October 2025

    Abstract Skin cancer is among the most common malignancies worldwide, but its mortality burden is largely driven by aggressive subtypes such as melanoma, with outcomes varying across regions and healthcare settings. These variations emphasize the importance of reliable diagnostic technologies that support clinicians in detecting skin malignancies with higher accuracy. Traditional diagnostic methods often rely on subjective visual assessments, which can lead to misdiagnosis. This study addresses these challenges by developing HybridFusionNet, a novel model that integrates Convolutional Neural Networks (CNN) with 1D feature extraction techniques to enhance diagnostic accuracy. Utilizing two extensive datasets, BCN20000 and… More >

  • Open Access

    ARTICLE

    Nationwide Trends in Congenital Heart Disease Surgery in Korea, 2002–2018: Volume, Age-Standardized Incidence, and Lesion-Based Case-Mix

    Jae Sung Son1, Soo-Jin Kim2,*

    Congenital Heart Disease, Vol.20, No.4, pp. 421-440, 2025, DOI:10.32604/chd.2025.070250 - 18 September 2025

    Abstract Background: Advancements in diagnostic tools, surgical techniques, and long-term management have significantly improved survival among individuals with congenital heart disease (CHD), leading to an evolving epidemiologic profile characterized by increasing procedural complexity and a growing adult CHD population. This study aimed to examine nationwide trends in CHD surgeries over a 17-year period, with a focus on temporal shifts in surgical volume, procedural complexity, and age-specific incidence. Methods: A total of 41,608 CHD surgeries and 85,417 surgical procedures performed between 2002 and 2018 were identified from a nationwide health insurance database. Temporal trends were evaluated using segmented… More >

  • Open Access

    CORRECTION

    Correction: Scheme Based on Multi-Level Patch Attention and Lesion Localization for Diabetic Retinopathy Grading

    Zhuoqun Xia1, Hangyu Hu1, Wenjing Li2,3, Qisheng Jiang1, Lan Pu1, Yicong Shu1, Arun Kumar Sangaiah4,5,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.2, pp. 2683-2683, 2025, DOI:10.32604/cmes.2025.069871 - 31 August 2025

    Abstract This article has no abstract. More >

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