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  • Open Access

    ARTICLE

    Phenolic Profiling and Bioactive Potential of Iris bucharica

    Olha Mykhailenko1,2,3,#,*, Zigmantas Gudžinskas4, Liudas Ivanauskas5, Victoriya Georgiyants1, Chia-Hung Yen6,7,8, Chung-Fan Hsieh9, Riong Seulina Panjaitan6, Tsong-Long Hwang10,11,12,13, Bing-Hung Chen14,15, Michal Korinek6,7,8,#,*

    Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2026.074209 - 30 January 2026

    Abstract The sustainable sourcing of novel bioactive compounds from natural sources is crucial to the success of the pharmaceutical, food, and cosmetics industries. Iris bucharica Foster (syn. Juno bucharica (Foster) Vved.) is a promising source of novel bioactive molecules, particularly phenolic compounds, which are renowned for their antioxidant properties. In this study, we developed a reliable HPLC-UV-DAD method to identify and quantify phenolic compounds in the leaves and bulbs of I. bucharica, establishing the first set of quality control markers for this species. A total of 21 phenolic compounds were identified in the leaves, with flavonoids isoorientin, guaijaverin, hyperoside, More >

  • Open Access

    ARTICLE

    Prediction of Root Zone Temperature Dynamics at Effective Depth on Lettuce Production in Greenhouse Using Sensitivity and Feature Importance Analysis with XGBoost

    Hasan Kaan Kucukerdem*

    Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2026.074188 - 30 January 2026

    Abstract Root-zone temperature (RZT) strongly affects plant growth, nutrient uptake and tolerance to environmental stress, making its regulation a key challenge in greenhouse cultivation in cold climates. This study aimed to assess the potential of passive techniques, namely black polyethylene mulch and row covers, for modifying RZT dynamics in lettuce (Lactuca sativa L.) production and to evaluate the predictive performance of the eXtreme Gradient Boosting (XGBoost) algorithm. Experiments were conducted in Iğdır, Türkiye, over a 61-day period, with soil temperature continuously monitored at depths of 1–30 cm under mulched and non-mulched conditions, alongside measurements of greenhouse air… More >

  • Open Access

    ARTICLE

    Algorithmically Enhanced Data-Driven Prediction of Shear Strength for Concrete-Filled Steel Tubes

    Shengkang Zhang1, Yong Jin2,*, Soon Poh Yap1,*, Haoyun Fan1, Shiyuan Li3, Ahmed El-Shafie4, Zainah Ibrahim1, Amr El-Dieb5

    CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2025.075351 - 29 January 2026

    Abstract Concrete-filled steel tubes (CFST) are widely utilized in civil engineering due to their superior load-bearing capacity, ductility, and seismic resistance. However, existing design codes, such as AISC and Eurocode 4, tend to be excessively conservative as they fail to account for the composite action between the steel tube and the concrete core. To address this limitation, this study proposes a hybrid model that integrates XGBoost with the Pied Kingfisher Optimizer (PKO), a nature-inspired algorithm, to enhance the accuracy of shear strength prediction for CFST columns. Additionally, quantile regression is employed to construct prediction intervals for… More >

  • Open Access

    REVIEW

    The Transparency Revolution in Geohazard Science: A Systematic Review and Research Roadmap for Explainable Artificial Intelligence

    Moein Tosan1,*, Vahid Nourani2,3, Ozgur Kisi4,5,6, Yongqiang Zhang7, Sameh A. Kantoush8, Mekonnen Gebremichael9, Ruhollah Taghizadeh-Mehrjardi10, Jinhui Jeanne Huang11

    CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2025.074768 - 29 January 2026

    Abstract The integration of machine learning (ML) into geohazard assessment has successfully instigated a paradigm shift, leading to the production of models that possess a level of predictive accuracy previously considered unattainable. However, the black-box nature of these systems presents a significant barrier, hindering their operational adoption, regulatory approval, and full scientific validation. This paper provides a systematic review and synthesis of the emerging field of explainable artificial intelligence (XAI) as applied to geohazard science (GeoXAI), a domain that aims to resolve the long-standing trade-off between model performance and interpretability. A rigorous synthesis of 87 foundational… More >

  • Open Access

    ARTICLE

    Noninvasive Radar Sensing Augmented with Machine Learning for Reliable Detection of Motor Imbalance

    Faten S. Alamri1, Adil Ali Saleem2, Muhammad I. Khan3, Hafeez Ur Rehman Siddiqui2, Amjad Rehman3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2025.074679 - 29 January 2026

    Abstract Motor imbalance is a critical failure mode in rotating machinery, potentially causing severe equipment damage if undetected. Traditional vibration-based diagnostic methods rely on direct sensor contact, leading to installation challenges and measurement artifacts that can compromise accuracy. This study presents a novel radar-based framework for non-contact motor imbalance detection using 24 GHz continuous-wave radar. A dataset of 1802 experimental trials was sourced, covering four imbalance levels (0, 10, 20, 30 g) across varying motor speeds (500–1500 rpm) and load torques (0–3 Nm). Dual-channel in-phase and quadrature radar signals were captured at 10,000 samples per second… More >

  • Open Access

    ARTICLE

    Explainable Ensemble Learning Framework for Early Detection of Autism Spectrum Disorder: Enhancing Trust, Interpretability and Reliability in AI-Driven Healthcare

    Menwa Alshammeri1,2,*, Noshina Tariq3, NZ Jhanji4,5, Mamoona Humayun6, Muhammad Attique Khan7

    CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2025.074627 - 29 January 2026

    Abstract Artificial Intelligence (AI) is changing healthcare by helping with diagnosis. However, for doctors to trust AI tools, they need to be both accurate and easy to understand. In this study, we created a new machine learning system for the early detection of Autism Spectrum Disorder (ASD) in children. Our main goal was to build a model that is not only good at predicting ASD but also clear in its reasoning. For this, we combined several different models, including Random Forest, XGBoost, and Neural Networks, into a single, more powerful framework. We used two different types More >

  • Open Access

    ARTICLE

    Concrete Strength Prediction Using Machine Learning and Somersaulting Spider Optimizer

    Marwa M. Eid1,2,*, Amel Ali Alhussan3, Ebrahim A. Mattar4, Nima Khodadadi5,*, El-Sayed M. El-Kenawy6,7

    CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.1, 2026, DOI:10.32604/cmes.2025.073555 - 29 January 2026

    Abstract Accurate prediction of concrete compressive strength is fundamental for optimizing mix designs, improving material utilization, and ensuring structural safety in modern construction. Traditional empirical methods often fail to capture the non-linear relationships among concrete constituents, especially with the growing use of supplementary cementitious materials and recycled aggregates. This study presents an integrated machine learning framework for concrete strength prediction, combining advanced regression models—namely CatBoost—with metaheuristic optimization algorithms, with a particular focus on the Somersaulting Spider Optimizer (SSO). A comprehensive dataset encompassing diverse mix proportions and material types was used to evaluate baseline machine learning models,… More >

  • Open Access

    ARTICLE

    CardioForest: An Explainable Ensemble Learning Model for Automatic Wide QRS Complex Tachycardia Diagnosis from ECG

    Vaskar Chakma1,#, Xiaolin Ju1,#, Heling Cao2, Xue Feng3, Xiaodong Ji3, Haiyan Pan3,*, Gao Zhan1,*

    Journal of Intelligent Medicine and Healthcare, Vol.4, pp. 37-86, 2026, DOI:10.32604/jimh.2026.075201 - 23 January 2026

    Abstract Wide QRS Complex Tachycardia (WCT) is a life-threatening cardiac arrhythmia requiring rapid and accurate diagnosis. Traditional manual ECG interpretation is time-consuming and subject to inter-observer variability, while existing AI models often lack the clinical interpretability necessary for trusted deployment in emergency settings. We developed CardioForest, an optimized Random Forest ensemble model, for automated WCT detection from 12-lead ECG signals. The model was trained, tested, and validated using 10-fold cross-validation on 800,000 ten-second-long 12-lead Electrocardiogram (ECG) recordings from the MIMIC-IV dataset (15.46% WCT prevalence), with comparative evaluation against XGBoost, LightGBM, and Gradient Boosting models. Performance was… More >

  • Open Access

    ARTICLE

    Machine Learning Models for Predicting Smoking-Related Health Decline and Disease Risk

    Vaskar Chakma1,*, Md Jaheid Hasan Nerab1, Abdur Rouf1, Abu Sayed2, Hossem Md Saim3, Md. Nournabi Khan3

    Journal of Intelligent Medicine and Healthcare, Vol.4, pp. 1-35, 2026, DOI:10.32604/jimh.2026.074347 - 23 January 2026

    Abstract Smoking continues to be a major preventable cause of death worldwide, affecting millions through damage to the heart, metabolism, liver, and kidneys. However, current medical screening methods often miss the early warning signs of smoking-related health problems, leading to late-stage diagnoses when treatment options become limited. This study presents a systematic comparative evaluation of machine learning approaches for smoking-related health risk assessment, emphasizing clinical interpretability and practical deployment over algorithmic innovation. We analyzed health screening data from 55,691 individuals, examining various health indicators including body measurements, blood tests, and demographic information. We tested three advanced… More >

  • Open Access

    ARTICLE

    Hederagenin Alleviated Ovariectomy-Induced Bone Loss through the Regulation of Innate Immune Signaling in Mice

    Zhitao Yang1,#, Huanyu Cheng1,#, Xinli Liu1, Jie Li1, Xin Ming1, Beibei Li1, Luyao Zhang1, Chunqing MA1, Yi Jiao1, Shenjia Wu1, Ibrar Muhammad Khan2, Guanghua Xiong1, Hongcheng Wang1,*, Yong Liu1,*

    BIOCELL, Vol.50, No.1, 2026, DOI:10.32604/biocell.2025.072736 - 23 January 2026

    Abstract Objectives: Postmenopausal osteoporosis is the most common form of osteoporosis in clinical practice, affecting millions of postmenopausal women worldwide. Postmenopausal osteoporosis demands safe and effective therapies. This study aimed to evaluate the potential of hederagenin (Hed) for treating osteoporosis and to elucidate its underlying mechanisms of action. Methods: The anti-osteoporotic potential of Hed was assessed by investigating its effects on ovariectomy (OVX)-induced bone loss in mice and on receptor activator of NF-kappaB ligand (RANKL)-induced osteoclast differentiation in RAW264.7 cells. Network pharmacology analysis and molecular docking were employed to identify key targets, which were subsequently validated experimentally. Results:More >

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