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  • Open Access

    ARTICLE

    Effects of NPK and Micronutrient Fertilization on Soil Enzyme Activities, Microbial Biomass, and Nutrient Availability

    Dilfuza Jabborova1,2,3,*, Khurshid Sulaymanov1, Muzafar Jabborov4, Nayan Ahmed5, Tatiana Minkina6, Olga Biryukova6, Nasir Mehmood6,*, Vishnu D. Rajput6

    Phyton-International Journal of Experimental Botany, Vol.95, No.1, 2026, DOI:10.32604/phyton.2026.072577 - 30 January 2026

    Abstract The combined effects of macronutrients (Nitrogen, Phosphorus, and Potassium-N, P, K) and micronutrient fertilization on turmeric yield, soil enzymatic activity, microbial biomass, and nutrient dynamics remains poorly understood, despite their significance for sustainable soil fertility management and optimizing crop productivity across diverse agroecosystems. To investigate, a net house experiment on sandy loam Haplic Chernozem was conducted to 03 fertilizer regimes, viz. N75P50K50 kg ha−1 (T-2), N125P100K100 kg ha−1 (T-3), and N100P75K75 + B3Zn6Fe6 kg ha−1 (T-4). Furthermore, the influence of these treatments was systematically assessed on soil nutrient status (N, P, K), enzymatic activities (alkaline phosphomonoesterase, dehydrogenase, fluorescein diacetate… More >

  • Open Access

    REVIEW

    Recent Advances in Hydrothermal Carbonization of Biomass: The Role of Process Parameters and the Applications of Hydrochar

    Cheng Zhang, Rui Zhang, Yu Shao, Jiabin Wang, Qianyue Yang, Fang Xie, Rongling Yang, Hongzhen Luo*

    Journal of Renewable Materials, Vol.14, No.1, 2026, DOI:10.32604/jrm.2025.02025-0157 - 23 January 2026

    Abstract Biomass is a resource whose organic carbon is formed from atmospheric carbon dioxide. It has numerous characteristics such as low carbon emissions, renewability, and environmental friendliness. The efficient utilization of biomass plays a significant role in promoting the development of clean energy, alleviating environmental pressures, and achieving carbon neutrality goals. Among the numerous processing technologies of biomass, hydrothermal carbonization (HTC) is a promising thermochemical process that can decompose and convert biomass into hydrochar under relatively mild conditions of approximately 180°C–300°C, thereby enabling its efficient resource utilization. In addition, HTC can directly process feedstocks with high… More >

  • Open Access

    ARTICLE

    BHLHE40 Is a Transcriptional Regulatory Target of NFE2L3 in Triple-Negative Breast Cancer

    Shail Rakesh Modi, Terrick Andey*, George Acquaah-Mensah*

    Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.070793 - 19 January 2026

    Abstract Objectives: The current treatment options and therapeutic targets for triple-negative breast cancer (TNBC), an aggressive subtype of breast cancer (BrCA), are limited. This study aimed to identify novel biomarkers and transcriptional regulatory networks (TRN) inherent in TNBC samples. Methods: We analyzed pan-cancer BrCA datasets from The Cancer Genome Atlas (TCGA) to compare triple-positive breast cancer (TPBC) with TNBC. TRN algorithms and virtual inference of protein-enriched regulon (VIPER) were used to identify master regulators and their target genes. Utilizing TNBC cells (MDA-MB-231 and MDA-MB-468), we validated the relationship of nuclear factor erythroid 2-like 3 (NFE2L3) and… More > Graphic Abstract

    <i>BHLHE40</i> Is a Transcriptional Regulatory Target of <i>NFE2L3</i> in Triple-Negative Breast Cancer

  • Open Access

    ARTICLE

    Utilization of a UPLC-MS/MS Approach to Elucidate the Role of ABCB1-Mediated Paclitaxel Resistance in Non-Small Cell Lung Cancer Cells

    Sha Hu1,2,#, Wenjing Wang1,#, Qianfang Hu3,#, Rujuan Zheng1,2, Qinghe Huang1,2, Hui Shi1,2, Xinyuan Ding3,*, Wenjuan Wang1,2,*, Zengyan Zhu1,2,*

    Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.068967 - 19 January 2026

    Abstract Objectives: Acquired resistance to paclitaxel represents a critical barrier to the effective chemotherapy of non-small cell lung cancer (NSCLC). The present study aimed to elucidate the molecular and pharmacological mechanisms promoting paclitaxel resistance in NSCLC and to explore potential strategies for overcoming this resistance. Methods: Here, we report an integrated pharmacological and analytical approach to quantify paclitaxel disposition and overcome resistance in a A549/TAX cell model (paclitaxel-resistant A549 cells). Results: Cell counting kit-8 (CCK-8) assay, colony formation, and apoptosis assays confirmed that A549/TAX cells exhibited marked resistance to paclitaxel relative to parental A549 cells. Based on… More >

  • Open Access

    ARTICLE

    CAWASeg: Class Activation Graph Driven Adaptive Weight Adjustment for Semantic Segmentation

    Hailong Wang1, Minglei Duan2, Lu Yao3, Hao Li1,*

    CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.072942 - 12 January 2026

    Abstract In image analysis, high-precision semantic segmentation predominantly relies on supervised learning. Despite significant advancements driven by deep learning techniques, challenges such as class imbalance and dynamic performance evaluation persist. Traditional weighting methods, often based on pre-statistical class counting, tend to overemphasize certain classes while neglecting others, particularly rare sample categories. Approaches like focal loss and other rare-sample segmentation techniques introduce multiple hyperparameters that require manual tuning, leading to increased experimental costs due to their instability. This paper proposes a novel CAWASeg framework to address these limitations. Our approach leverages Grad-CAM technology to generate class activation… More >

  • Open Access

    ARTICLE

    A Dynamic Masking-Based Multi-Learning Framework for Sparse Classification

    Woo Hyun Park*, Dong Ryeol Shin

    CMC-Computers, Materials & Continua, Vol.86, No.3, 2026, DOI:10.32604/cmc.2025.069949 - 12 January 2026

    Abstract With the recent increase in data volume and diversity, traditional text representation techniques are struggling to capture context, particularly in environments with sparse data. To address these challenges, this study proposes a new model, the Masked Joint Representation Model (MJRM). MJRM approximates the original hypothesis by leveraging multiple elements in a limited context. It dynamically adapts to changes in characteristics based on data distribution through three main components. First, masking-based representation learning, termed selective dynamic masking, integrates topic modeling and sentiment clustering to generate and train multiple instances across different data subsets, whose predictions are… More >

  • Open Access

    ARTICLE

    The Impact of EU Immigration Law and Policy on Immigrants’ Subjective Well-Being

    Quan Cheng, Yun Lin, Hui Yu*

    International Journal of Mental Health Promotion, Vol.27, No.12, pp. 1961-1988, 2025, DOI:10.32604/ijmhp.2025.072232 - 31 December 2025

    Abstract Background: Against the backdrop of the complex interplay between global migration flows and the European Union’s governance system, immigrants’ subjective well-being (SWB) has become a crucial indicator for assessing both their social integration and the effectiveness of integration policies. However, few studies have systematically linked immigration law and policy to SWB through a structured framework of human needs. This study aims to assess how European Union (EU) immigration policies influence immigrants’ SWB by facilitating the fulfillment of hierarchical needs based on Maslow’s theory. Methods: Using data from the European Social Survey (ESS, 2010–2023), this study analyzed… More >

  • Open Access

    ARTICLE

    Chemical Composition and Antifungal Efficacy of Mentha rotundifolia Essential Oil against Fusarium oxysporum f. sp. albedinis in Date Palm: Valorisation of Plant Biomass for Natural Antifungal Agents

    Hafida Khelafi1, Wassima Lakhdari2, Mustapha Mounir Bouhenna3, Said Boudeffeur4, Hayet Meamiche1, Salah Neghmouche Nacer5,*, Meriam Laouar6

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3975-3989, 2025, DOI:10.32604/phyton.2025.073210 - 29 December 2025

    Abstract Essential oils (EOs) derived from medicinal plants are gaining recognition as sustainable alternatives to synthetic fungicides in the management of plant pathogens. This study investigates the chemical composition, chromatographic profile, and antifungal of Mentha rotundifolia essential oil against Fusarium oxysporum f. sp. albedinis (Foa), the pathogen responsible for Bayoud disease in date palm. The oil was extracted through hydrodistillation and characterized using thin-layer chromatography (TLC) and gas chromatography–mass spectrometry (GC-MS), revealing multiple fractions corresponding to terpenoid constituents and 23 chemical constituents, predominantly oxygenated monoterpenes (68.51%), with piperitenone oxide as the major component (62.53%). The antifungal efficacy was evaluated… More >

  • Open Access

    ARTICLE

    Chitosan-Selenate Complex Improves Bioactive Profile and Antioxidant Response in Wheat Sprouts (Triticum aestivum L.)

    Jazmín Montserrat Gaucin-Delgado1, Cristian Oswaldo Solis-López2, Pablo Preciado-Rangel3, Bernardo Espinosa-Palomeque4, Francisco Gerardo Veliz-Deras2, Viridiana Contreras-Villarreal2, Ricardo Israel Ramírez-Gottfried5,*

    Phyton-International Journal of Experimental Botany, Vol.94, No.12, pp. 3961-3973, 2025, DOI:10.32604/phyton.2025.072536 - 29 December 2025

    Abstract Selenium (Se) deficiency is a global health problem affecting more than 500 million people; crop biofortification is a sustainable strategy for its mitigation. This study investigated the effect of the application of selenate nanoparticles (SeO42−) and the combination of selenate (SeO42−) and chitosan (CS) (forming a SeO42−-CS complex) on the antioxidant profile, growth, biomass, bioactive compounds, enzymes, and Se accumulation of wheat (Triticum spp.) sprouts. Fourteen treatments were applied using a factorial design combining seven concentrations and two formulations: SeO42− and SeO42−-CS. It was identified that chitosan increased Se uptake efficiency by 30% versus conventional selenate. The optimal… More >

  • Open Access

    ARTICLE

    Analytical Modeling of Internal Thermal Mass: Transient Heat Conduction in a Sphere under Constant, Exponential, and Periodic Ambient Temperatures

    Liangjian Lei1,2, Yihang Lu1,2,*

    Frontiers in Heat and Mass Transfer, Vol.23, No.6, pp. 2109-2126, 2025, DOI:10.32604/fhmt.2025.072643 - 31 December 2025

    Abstract Internal thermal mass, such as furniture and partitions, plays a crucial role in enhancing building energy efficiency and indoor thermal comfort by passively regulating temperature fluctuations. However, the irregular geometry of these elements poses a significant challenge for accurate modeling in building energy simulations. This study addresses this gap by developing a rigorous analytical model that idealizes internal thermal mass as a sphere, thereby capturing multi-directional heat conduction effects that are neglected in simpler one-dimensional slab models. The transient heat conduction within the sphere is solved analytically using Duhamel’s theorem for three representative indoor air… More >

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