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  • Open Access

    ARTICLE

    Physics-Informed Neural Networks for Hail-Impact Dynamics of Photovoltaic Panels: Multi-Condition Forward Modeling and Inverse Identification of Contact Stiffness

    Hassaan Idrees1,*, Pattabhi Ramaiah Budarapu2, Marco Paggi1,*

    CMC-Computers, Materials & Continua, Vol.89, No.2, 2026, DOI:10.32604/cmc.2026.085634 - 15 September 2026

    Abstract Hail impacts on photovoltaic laminates generate strongly nonlinear contact forces whose polynomial restoring form and coefficients govern the resulting damage pattern. Predicting the dynamic response across a range of impact velocities, and inferring substrate properties from post-event vibration measurements, are two tasks that classical time-integration schemes do not address in a unified manner. This work develops a physics-informed neural network (PINN) framework that handles both. For the forward problem, the network is conditioned on the initial velocity and trained simultaneously at four representative hail-impact speeds, i.e., v0{2,3,4,6} m/s, so that it learns… More >

  • Open Access

    ARTICLE

    The Impact of Combretastatin A-4 on Cancer Cells and Circulating Tumor Cells (CTCs): A Multi-Assay Approach

    Dimitrios Papakonstantinou1, Vasileios Vardas1, Despoina M. Varouhaki2, Aikaterini Kotzamouratoglou1, Karolina Mangani1, Julia A. Ju3, Catherine Alix-Panabières4,5,6, Stuart S. Martin3, Constantinos M. Athanassopoulos2, Galatea Kallergi1,*

    Oncology Research, Vol.34, No.10, 2026, DOI:10.32604/or.2026.085665 - 14 September 2026

    Abstract Objectives: Combretastatin A-4 (CA-4) is a microtubule-disrupting agent with established anti-tumor properties. This study aimed to evaluate the effects of CA-4 on key metastatic traits of cancer cells, including migration, clonogenic potential, cytoskeletal protein expression, and microtentacle (McTN) formation, using multiple cancer cell models, including the colon patient-derived circulating tumor cell line CTC-MCC-41. Methods: H1299 (non-small cell lung cancer), MDA-MB-231 (triple-negative breast cancer), HT-29 (colorectal cancer), and CTC-MCC-41 (derived from the blood of a colon cancer patient) cells were treated with CA-4 (10 μM) for 24 and 48 h. Colony formation was assessed with a clonogenic… More > Graphic Abstract

    The Impact of Combretastatin A-4 on Cancer Cells and Circulating Tumor Cells (CTCs): A Multi-Assay Approach

  • Open Access

    ARTICLE

    Comparison of Neoadjuvant Chemotherapy, Chemoimmunotherapy, and Upfront Radical Cystectomy in High-Risk Bladder Cancer: A Single-Center Retrospective Study

    Shaohua Chen1,#, Xiao Gan1,#, Ping Lv1,#, Qinggui Meng1, Xiaocao Lin1,2,*, Qingyun Zhang1,2,*

    Oncology Research, Vol.34, No.10, 2026, DOI:10.32604/or.2026.083704 - 14 September 2026

    Abstract Background: While radical cystectomy is standard for muscle-invasive bladder cancer (MIBC), micrometastasis-related recurrence is common. Cisplatin-based neoadjuvant therapy (NAT) confers modest benefits, while immune checkpoint inhibitors (ICIs) provide new efficacy-enhancing strategies. This study aims to compare the efficacy and safety of ICIs with chemotherapy (NAC-ICI), neoadjuvant chemotherapy (NAC), and no neoadjuvant therapy (NNAT). It also explores potential biomarkers predictive of NAT response and evaluates the real-world efficacy of NAC-IC. Method: This single-center retrospective analysis included 80 radical cystectomy patients, with 51 NNAT group and 29 in the NAT group. Survival outcomes were evaluated by Kaplan-Meier survival… More >

  • Open Access

    ARTICLE

    Erosion of Metal Wire Mesh Screens under Varying Flow Velocity, Sand Concentration, and Impact Angle

    Baocheng Shi1,2,*, Minyi Yang2, Zhibin Wang1, Qing Yuan2, Jiang Bian2, Yajun Deng2, Kai Liu2

    FDMP-Fluid Dynamics & Materials Processing, Vol.22, No.8, 2026, DOI:10.32604/fdmp.2026.087023 - 04 September 2026

    Abstract This study investigates the erosion behavior of metal mesh sand-control screens under representative operating conditions and develops an empirical model for predicting erosion rate and screen service life. Single-layer metal mesh screens were tested using a Multifunctional Spin Hydrodynamics (MSH) rotating apparatus under systematically varied liquid velocity, sand concentration, and particle impact angle. The influence of each operating parameter on erosion was quantified using a one-factor-at-a-time experimental design, while the underlying wear mechanisms were characterized by scanning electron microscopy (SEM) and optical microscopy. The results show that liquid velocity is the dominant factor controlling erosion, More >

  • Open Access

    ARTICLE

    Longitudinal Association between Negative Family Representations and Depression in High School Students: The Mediating Role of Cognitive Failure and the Moderating Role of Self-Compassion

    Han Qi1, Zhihong Liu2, Shanshan Zhang1,*, Fengmin Guo3

    International Journal of Mental Health Promotion, Vol.28, No.8, 2026, DOI:10.32604/ijmhp.2026.081464 - 31 August 2026

    Abstract Backgrounds: High school is a critical period for psychological development, during which mental health is vulnerable to family environment. According to attachment theory, adolescents exposed to conflicting family environments develop negative internal working models, characterized by doubts about the stability of parental relationships and family support (i.e., negative family representations). These negative representations constitute a cognitive basis for depression risk. However, the mediating and protective mechanisms remain unclear. Thus, the primary purpose of this study is to explore the potential effect of negative family representations on depression among high school students, focusing on the mediating role… More >

  • Open Access

    ARTICLE

    Understanding Social Media Addiction through the S-O-R Framework: The Mediating Roles of Cognitive and Behavioral Paths

    Huimin Yin1, Difan Guo2,*

    International Journal of Mental Health Promotion, Vol.28, No.8, 2026, DOI:10.32604/ijmhp.2026.081018 - 31 August 2026

    Abstract Background: While social media enhances information accessibility and connectivity, excessive use has prompted research into social media addiction (SMA). However, pathways linking psychological stimuli to addictive behaviors remain unclear. This study examined how boredom proneness, social comparison, and anxiety relate to SMA through two mechanisms: information overload and social media stalking. Within the Stimulus–Organism–Response (S-O-R) framework, this research explains how psychological predispositions influence SMA through cognitive and behavioral mechanisms. Methods: A cross-sectional survey of 258 active social media participants examined associations between psychological predispositions and SMA. Structural equation modeling (SEM) was applied to examine the hypothesized… More >

  • Open Access

    ARTICLE

    The Impact of Music Education Intervention on Anxiety Symptoms among Non-Music Major University Students: A Quasi-Experimental Study

    Pengpeng Yang*, Anne Noor Sri Juwaneeta Jamaludin

    International Journal of Mental Health Promotion, Vol.28, No.8, 2026, DOI:10.32604/ijmhp.2026.080765 - 31 August 2026

    Abstract Backgrounds: Anxiety symptoms represent a prevalent mental health challenge among university students, yet accessible and scalable intervention approaches remain limited. This study examined the effectiveness of a structured music education intervention in reducing anxiety symptoms among non-music major university students in China. Methods: Using a quasi-experimental design with a non-equivalent control group, 110 participants experiencing anxiety symptoms were allocated to either an intervention group (n = 55) receiving a 12-week music education program comprising two 90-min sessions weekly, or a control group (n = 55) continuing regular academic activities. Assessments were conducted at baseline (T0), post-intervention… More >

  • Open Access

    REVIEW

    The Impacts of AI on College Students’ Mental Health and Well-Being in Higher Education System: A Systematic Review Approach

    Jian Li1,*, Chenxi Zhang2,*, Eryong Xue2,*

    International Journal of Mental Health Promotion, Vol.28, No.8, 2026, DOI:10.32604/ijmhp.2026.080105 - 31 August 2026

    Abstract Background: The role of artificial intelligence in influencing the mental health and well-being of students in higher education has become increasingly significant globally and locally. However, there is still a paucity of research that systematically investigates the effects of artificial intelligence on students’ psychological health and well-being from a comprehensive perspective. Methods: Followed the Prisma 2020 guidelines, this study employs a systematic literature review to examine the impacts of artificial intelligence on college students’ mental health and well-being in higher education contexts. Data were obtained from three major academic databases—Scopus, the (EBSCOhost) Research Databases, and the… More >

  • Open Access

    ARTICLE

    Cybervictimization and college students’ sleep quality: The mediating role of rumination and the moderating role of self-compassion

    Yue Guo1, Zhenlu Bao2, Zhenlin Lei3, Rui Wang4, Jiawei Guo5,*

    Journal of Psychology in Africa, Vol.36, No.4, pp. 537-544, 2026, DOI:10.32604/jpa.2026.083642 - 31 August 2026

    Abstract The present study examined the association between cybervictimization and sleep quality among university students, focusing on the mediating role of rumination and the moderating role of self-compassion. Participants were 932 students (mean age = 19.74 years; 53.76% female). They completed self-report questionnaires assessing cybervictimization, rumination, self-compassion, and sleep quality. The results from mediation-moderation analysis showed that cybervictimization was positively associated with poorer sleep quality. Rumination mediated this relationship, suggesting that university students exposed to cybervictimization were more likely to engage in repetitive negative thinking, which in turn associated with worse sleep outcomes. Furthermore, self-compassion moderated More >

  • Open Access

    ARTICLE

    Risk and protective configurations for adjustment difficulties among university freshmen

    Yuxin (Lorraine) Zhang1,2,*

    Journal of Psychology in Africa, Vol.36, No.4, pp. 525-535, 2026, DOI:10.32604/jpa.2026.082443 - 31 August 2026

    Abstract University entry is a psychologically demanding transition. Adjustment difficulties are a leading mental health concern among Chinese freshmen. This study examined psychological configurations associated with adjustment difficulties among university freshmen. Participants were 356 first-year students (50.6% female; aged 18–20) who completed measures of self-identity exploration, sense of belonging, psychological resilience, neuroticism, extraversion, and adjustment difficulties. Fuzzy-set qualitative comparative analysis and Necessary Condition Analysis identified configurations. Three risk configurations emerged: resource depletion combining absent identity exploration, absent resilience, and absent extraversion; relational deficit combining absent identity exploration, absent belonging, and resilience; and emotional vulnerability combining absent More >

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