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  • Open Access

    ARTICLE

    A Hybrid Deep Learning Multi-Class Classification Model for Alzheimer’s Disease Using Enhanced MRI Images

    Ghadah Naif Alwakid*

    CMC-Computers, Materials & Continua, Vol.86, No.1, pp. 1-25, 2026, DOI:10.32604/cmc.2025.068666 - 10 November 2025

    Abstract Alzheimer’s Disease (AD) is a progressive neurodegenerative disorder that significantly affects cognitive function, making early and accurate diagnosis essential. Traditional Deep Learning (DL)-based approaches often struggle with low-contrast MRI images, class imbalance, and suboptimal feature extraction. This paper develops a Hybrid DL system that unites MobileNetV2 with adaptive classification methods to boost Alzheimer’s diagnosis by processing MRI scans. Image enhancement is done using Contrast-Limited Adaptive Histogram Equalization (CLAHE) and Enhanced Super-Resolution Generative Adversarial Networks (ESRGAN). A classification robustness enhancement system integrates class weighting techniques and a Matthews Correlation Coefficient (MCC)-based evaluation method into the design.… More >

  • Open Access

    ARTICLE

    An Efficient Explainable AI Model for Accurate Brain Tumor Detection Using MRI Images

    Fatma M. Talaat1,2,*, Mohamed Salem1, Mohamed Shehata3,4,*, Warda M. Shaban5

    CMES-Computer Modeling in Engineering & Sciences, Vol.144, No.2, pp. 2325-2358, 2025, DOI:10.32604/cmes.2025.067195 - 31 August 2025

    Abstract The diagnosis of brain tumors is an extended process that significantly depends on the expertise and skills of radiologists. The rise in patient numbers has substantially elevated the data processing volume, making conventional methods both costly and inefficient. Recently, Artificial Intelligence (AI) has gained prominence for developing automated systems that can accurately diagnose or segment brain tumors in a shorter time frame. Many researchers have examined various algorithms that provide both speed and accuracy in detecting and classifying brain tumors. This paper proposes a new model based on AI, called the Brain Tumor Detection (BTD)… More >

  • Open Access

    ARTICLE

    Transformation of MRI Images to Three-Level Color Spaces for Brain Tumor Classification Using Deep-Net

    Fadl Dahan*

    Intelligent Automation & Soft Computing, Vol.39, No.2, pp. 381-395, 2024, DOI:10.32604/iasc.2024.047921 - 21 May 2024

    Abstract In the domain of medical imaging, the accurate detection and classification of brain tumors is very important. This study introduces an advanced method for identifying camouflaged brain tumors within images. Our proposed model consists of three steps: Feature extraction, feature fusion, and then classification. The core of this model revolves around a feature extraction framework that combines color-transformed images with deep learning techniques, using the ResNet50 Convolutional Neural Network (CNN) architecture. So the focus is to extract robust feature from MRI images, particularly emphasizing weighted average features extracted from the first convolutional layer renowned for… More >

  • Open Access

    ARTICLE

    Intelligent Machine Learning Based Brain Tumor Segmentation through Multi-Layer Hybrid U-Net with CNN Feature Integration

    Sharaf J. Malebary*

    CMC-Computers, Materials & Continua, Vol.79, No.1, pp. 1301-1317, 2024, DOI:10.32604/cmc.2024.047917 - 25 April 2024

    Abstract Brain tumors are a pressing public health concern, characterized by their high mortality and morbidity rates. Nevertheless, the manual segmentation of brain tumors remains a laborious and error-prone task, necessitating the development of more precise and efficient methodologies. To address this formidable challenge, we propose an advanced approach for segmenting brain tumor Magnetic Resonance Imaging (MRI) images that harnesses the formidable capabilities of deep learning and convolutional neural networks (CNNs). While CNN-based methods have displayed promise in the realm of brain tumor segmentation, the intricate nature of these tumors, marked by irregular shapes, varying sizes,… More >

  • Open Access

    ARTICLE

    SC-Net: A New U-Net Network for Hippocampus Segmentation

    Xinyi Xiao, Dongbo Pan*, Jianjun Yuan

    Intelligent Automation & Soft Computing, Vol.37, No.3, pp. 3179-3191, 2023, DOI:10.32604/iasc.2023.041208 - 11 September 2023

    Abstract Neurological disorders like Alzheimer’s disease have a significant impact on the lives and health of the elderly as the aging population continues to grow. Doctors can achieve effective prevention and treatment of Alzheimer’s disease according to the morphological volume of hippocampus. General segmentation techniques frequently fail to produce satisfactory results due to hippocampus’s small size, complex structure, and fuzzy edges. We develop a new SC-Net model using complete brain MRI images to achieve high-precision segmentation of hippocampal structures. The proposed network improves the accuracy of hippocampal structural segmentation by retaining the original location information of More >

  • Open Access

    ARTICLE

    SNCDM: Spinal Tumor Detection from MRI Images Using Optimized Super-Pixel Segmentation

    T. Merlin Inbamalar1,*, Dhandapani Samiappan2, R. Ramesh3

    Intelligent Automation & Soft Computing, Vol.36, No.2, pp. 1899-1913, 2023, DOI:10.32604/iasc.2023.031202 - 05 January 2023

    Abstract Conferring to the American Association of Neurological Surgeons (AANS) survey, 85% to 99% of people are affected by spinal cord tumors. The symptoms are varied depending on the tumor’s location and size. Up-to-the-minute, back pain is one of the essential symptoms, but it does not have a specific symptom to recognize at the earlier stage. Numerous significant research studies have been conducted to improve spine tumor recognition accuracy. Nevertheless, the traditional systems are consuming high time to extract the specific region and features. Improper identification of the tumor region affects the predictive tumor rate and More >

  • Open Access

    ARTICLE

    CE-EEN-B0: Contour Extraction Based Extended EfficientNet-B0 for Brain Tumor Classification Using MRI Images

    Abishek Mahesh1, Deeptimaan Banerjee1, Ahona Saha1, Manas Ranjan Prusty2,*, A. Balasundaram2

    CMC-Computers, Materials & Continua, Vol.74, No.3, pp. 5967-5982, 2023, DOI:10.32604/cmc.2023.033920 - 28 December 2022

    Abstract A brain tumor is the uncharacteristic progression of tissues in the brain. These are very deadly, and if it is not diagnosed at an early stage, it might shorten the affected patient’s life span. Hence, their classification and detection play a critical role in treatment. Traditional Brain tumor detection is done by biopsy which is quite challenging. It is usually not preferred at an early stage of the disease. The detection involves Magnetic Resonance Imaging (MRI), which is essential for evaluating the tumor. This paper aims to identify and detect brain tumors based on their… More >

  • Open Access

    ARTICLE

    De-Noising Brain MRI Images by Mixing Concatenation and Residual Learning (MCR)

    Kazim Ali1,*, Adnan N. Qureshi1, Muhammad Shahid Bhatti2, Abid Sohail2, Muhammad Hijji3, Atif Saeed2

    Computer Systems Science and Engineering, Vol.45, No.2, pp. 1167-1186, 2023, DOI:10.32604/csse.2023.032508 - 03 November 2022

    Abstract Brain magnetic resonance images (MRI) are used to diagnose the different diseases of the brain, such as swelling and tumor detection. The quality of the brain MR images is degraded by different noises, usually salt & pepper and Gaussian noises, which are added to the MR images during the acquisition process. In the presence of these noises, medical experts are facing problems in diagnosing diseases from noisy brain MR images. Therefore, we have proposed a de-noising method by mixing concatenation, and residual deep learning techniques called the MCR de-noising method. Our proposed MCR method is… More >

  • Open Access

    ARTICLE

    Machine Learning-Based Models for Magnetic Resonance Imaging (MRI)-Based Brain Tumor Classification

    Abdullah A. Asiri1, Bilal Khan2, Fazal Muhammad3,*, Shams ur Rahman4, Hassan A. Alshamrani1, Khalaf A. Alshamrani1, Muhammad Irfan5, Fawaz F. Alqhtani1

    Intelligent Automation & Soft Computing, Vol.36, No.1, pp. 299-312, 2023, DOI:10.32604/iasc.2023.032426 - 29 September 2022

    Abstract In the medical profession, recent technological advancements play an essential role in the early detection and categorization of many diseases that cause mortality. The technique rising on daily basis for detecting illness in magnetic resonance through pictures is the inspection of humans. Automatic (computerized) illness detection in medical imaging has found you the emergent region in several medical diagnostic applications. Various diseases that cause death need to be identified through such techniques and technologies to overcome the mortality ratio. The brain tumor is one of the most common causes of death. Researchers have already proposed… More >

  • Open Access

    ARTICLE

    Multi-Level Deep Generative Adversarial Networks for Brain Tumor Classification on Magnetic Resonance Images

    Abdullah A. Asiri1, Ahmad Shaf2,*, Tariq Ali2, Muhammad Aamir2, Ali Usman2, Muhammad Irfan3, Hassan A. Alshamrani1, Khlood M. Mehdar4, Osama M. Alshehri5, Samar M. Alqhtani6

    Intelligent Automation & Soft Computing, Vol.36, No.1, pp. 127-143, 2023, DOI:10.32604/iasc.2023.032391 - 29 September 2022

    Abstract The brain tumor is an abnormal and hysterical growth of brain tissues, and the leading cause of death affected patients worldwide. Even in this technology-based arena, brain tumor images with proper labeling and acquisition still have a problem with the accurate and reliable generation of realistic images of brain tumors that are completely different from the original ones. The artificially created medical image data would help improve the learning ability of physicians and other computer-aided systems for the generation of augmented data. To overcome the highlighted issue, a Generative Adversarial Network (GAN) deep learning technique… More >

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