Yuan-Nong Ye^1,2,3,*, Ding-Fa Liang², Abraham Alemayehu Labena⁴, Zhu Zeng^2,*

Intelligent Automation & Soft Computing, Vol.36, No.3, pp. 2731-2741, 2023, DOI:10.32604/iasc.2023.026761

Abstract Essential ncRNA is a type of ncRNA which is indispensable for the survival of organisms. Although essential ncRNAs cannot encode proteins, they are as important as essential coding genes in biology. They have got wide variety of applications such as antimicrobial target discovery, minimal genome construction and evolution analysis. At present, the number of species required for the determination of essential ncRNAs in the whole genome scale is still very few due to the traditional methods are time-consuming, laborious and costly. In addition, traditional experimental methods are limited by the organisms as less than 1% of bacteria can be cultured… More >

Saleh Albahli¹, Tahira Nazir^2,*, Aun Irtaza², Ali Javed³

CMC-Computers, Materials & Continua, Vol.67, No.2, pp. 1333-1351, 2021, DOI:10.32604/cmc.2021.014691

Abstract Diabetes is a metabolic disorder that results in a retinal complication called diabetic retinopathy (DR) which is one of the four main reasons for sightlessness all over the globe. DR usually has no clear symptoms before the onset, thus making disease identification a challenging task. The healthcare industry may face unfavorable consequences if the gap in identifying DR is not filled with effective automation. Thus, our objective is to develop an automatic and cost-effective method for classifying DR samples. In this work, we present a custom Faster-RCNN technique for the recognition and classification of DR lesions from retinal images. After… More >

Hyeong Won Yu¹, Muhammad Afzal², Maqbool Hussain², Hyungju Kwon³, Young Joo Park⁴, June Young Choi^1,*, Kyu Eun Lee⁵

CMC-Computers, Materials & Continua, Vol.67, No.1, pp. 1241-1251, 2021, DOI:10.32604/cmc.2021.014910

Abstract Advances in technology are enabling gene mutations in papillary thyroid carcinoma (PTC) to be analyzed and clinical outcomes, such as recurrence, to be predicted. To date, the most common genetic mutation in PTC is in BRAF kinase (BRAF). However, whether mutations in other genes coincide with those in BRAF remains to be clarified. The aim of this study was to find mutations in other genes that co-exist with mutated BRAF, and to analyze their frequency and clinical relevance in PTC. Clinical and genetic data were collected from 213 PTC patients with a total of 36,572 mutation sites in 735 genes.… More >