TIECHENG SUN1,#, LINGLI SONG1,#, JING MA2,#, HONG YU1, SHANJIE ZHOU1, SHUSONG WANG2, LI TIAN1,3,*
BIOCELL, Vol.44, No.4, pp. 479-485, 2020, DOI:10.32604/biocell.2020.011675
Abstract Melatonin, as a ubiquitous indoleamine hormone, is synthesized primarily by the pineal gland. It has diverse
biological effects through quite complex mechanisms. More recently, studies have focused on the mechanism of
melatonin in anti-reproductive toxicity/damage. Since melatonin possesses strong antioxidant and anti-apoptotic
properties, researchers have examined its potential role in protecting against male reproductive toxicity/damage,
which may be induced by chemotherapy or environmental toxicants and can lead to male infertility. In this article,
recent progress regarding the protective effects of melatonin on male reproductive toxicity/damage is reviewed. More >
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