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  • Open Access

    REVIEW

    Targeting brain tumors with innovative nanocarriers: bridging the gap through the blood-brain barrier

    KARAN WADHWA1, PAYAL CHAUHAN1, SHOBHIT KUMAR2, RAKESH PAHWA3,*, RAVINDER VERMA4, RAJAT GOYAL5, GOVIND SINGH1, ARCHANA SHARMA6, NEHA RAO3, DEEPAK KAUSHIK1,*

    Oncology Research, Vol.32, No.5, pp. 877-897, 2024, DOI:10.32604/or.2024.047278

    Abstract Background: Glioblastoma multiforme (GBM) is recognized as the most lethal and most highly invasive tumor. The high likelihood of treatment failure arises from the presence of the blood-brain barrier (BBB) and stem cells around GBM, which avert the entry of chemotherapeutic drugs into the tumor mass. Objective: Recently, several researchers have designed novel nanocarrier systems like liposomes, dendrimers, metallic nanoparticles, nanodiamonds, and nanorobot approaches, allowing drugs to infiltrate the BBB more efficiently, opening up innovative avenues to prevail over therapy problems and radiation therapy. Methods: Relevant literature for this manuscript has been collected from a comprehensive and systematic search of… More > Graphic Abstract

    Targeting brain tumors with innovative nanocarriers: bridging the gap through the blood-brain barrier

  • Open Access

    REVIEW

    Synthesis of Metallic Nanoparticles Based on Green Chemistry and Their Medical Biochemical Applications: Synthesis of Metallic Nanoparticles

    Kakudji Kisimba1, Anand Krishnan2,*, Mbuso Faya1, Kahumba Byanga3, Kabange Kasumbwe4, Kaliyapillai Vijayakumar5, Ram Prasad6,*

    Journal of Renewable Materials, Vol.11, No.6, pp. 2575-2591, 2023, DOI:10.32604/jrm.2023.026159

    Abstract Nanoparticles have distinct properties that make them potentially valuable in a variety of industries. As a result, emerging approaches for the manufacture of nanoparticles are gaining a lot of scientific interest. The biological pathway of nanoparticle synthesis has been suggested as an effective, affordable, and environmentally safe method. Synthesis of nanoparticles through physical and chemical processes uses unsafe materials, expensive equipment and adversely affects the environment. As a result, in order to support the increased utilization of nanoparticles across many sectors, nanotechnology research activities have shifted toward environmentally safe and cost-effective techniques that outperform chemical and/or biological procedures. The use… More > Graphic Abstract

    Synthesis of Metallic Nanoparticles Based on Green Chemistry and Their Medical Biochemical Applications: Synthesis of Metallic Nanoparticles

  • Open Access

    ARTICLE

    Insecticidal Effect of Green Bimetallic Nanoparticles from Crotalaria longirostrata on Cotton Mealybug, Phenacoccus solenopsis

    Vianey Mendez-Trujillo1, Benjamín Valdez-Salas2, Mario Curiel-Alvarez2, Ernesto Beltran-Partida2, Arnoldo Alfaro-Corres3, Esaú Ruiz-Sanchez3, Gerardo Bautista-Trujillo4, Olivia Tzintzun Camacho5, Onecimo Grimaldo-Juarez5, Carlos Ceceña-Duran5, Carlos Ail-Catzin5, Daniel González-Mendoza5,*

    Journal of Renewable Materials, Vol.10, No.10, pp. 2543-2552, 2022, DOI:10.32604/jrm.2022.020965

    Abstract The present study was conducted to evaluate the impact of bimetallic nanoparticles (NPs) of copper (Cu) and zinc (Zn) from Crotalaria longirostrata on the insect mortality and cell viability of Phenacoccus solenopsis. The biosynthesis of bimetallic nanoparticles (Cu/Zn-NPs) from C. longirostrata was confirmed by the presence of a single peak around 378 nm. The hydrodynamic diameter of the Cu/Zn nanoparticles varied from 59 to 119 nm and their zeta potential was found to be −30.90 mV. The EDX analysis showed a strong signal for Cu and Zn (8 and 8.6 keV, respectively). The Cu/Zn-NPs showed an effective insecticide activity against P. solenopsis with 63%… More >

  • Open Access

    ARTICLE

    Green Synthesis of Bimetallic Nanoparticles From Prosopis juliflora (Sw) DC., and Its Effect Against Cotton Mealybug, Phenacoccus solenopsis (Hemiptera: Pseudococcidae)

    V. Mendez-Trujillo1, B. Valdez-Salas2, M. Carrillo-Beltran2, M. A. Curiel-Alvarez2, O. Tzintzun-Camacho3, C. Ceceña-Duran3 and D. Gonzalez-Mendoza3,*

    Phyton-International Journal of Experimental Botany, Vol.88, No.3, pp. 269-275, 2019, DOI:10.32604/phyton.2019.07316

    Abstract Phenacoccus solenopsis has been recognized as an aggressively invasive species on cotton plants in different countries. This study was conducted to investigate the effect of green synthesized Cu/Zn-nanoparticles using aqueous leaf extract of Prosopis juliflora (mezquite) against P. solenopsis. The scanning electron microscope (SEM) showed bimetallic nanoparticles of Cu/Zn-NPs with spherical shape with varying size of 74.33 nm to 59.46 nm. More than 30% mortality of P. solenopsis was observed with Cu/Zn-nanoparticles (100 ppm) at 96 hours after treatment. Negligible mortality of P. solenopsis was recorded with Cu/Zn solution (100 ppm) and aqueous P. juliflora extracts. The results of the… More >

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