Samuel Acheme^*, Glory Nosawaru Edegbe

Journal of Cyber Security, Vol.8, pp. 1-31, 2026, DOI:10.32604/jcs.2026.073923 - 07 January 2026

Abstract Federated learning (FL) enables collaborative model training across decentralized datasets, thus maintaining the privacy of training data. However, FL remains vulnerable to malicious actors, posing significant risks in privacy-sensitive domains like healthcare. Previous machine learning trust frameworks, while promising, often rely on resource-intensive blockchain ledgers, introducing computational overhead and metadata leakage risks. To address these limitations, this study presents a novel Decentralized Identity (DID) framework for mutual authentication that establishes verifiable trust among participants in FL without dependence on centralized authorities or high-cost blockchain ledgers. The proposed system leverages Decentralized Identifiers (DIDs) and Verifiable Credentials… More >

Wu Feng^1,2,*, Tengku Anita Raja Hussin¹, Xu Yang³

Structural Durability & Health Monitoring, Vol.20, No.1, 2026, DOI:10.32604/sdhm.2025.071664 - 08 January 2026

Abstract This study investigates the thermo–mechanical behavior of C40 concrete and reinforced concrete subjected to elevated temperatures up to 700°C by integrating experimental testing and advanced numerical modeling. A temperature-indexed Concrete Damage Plasticity (CDP) framework incorporating bond–slip effects was developed in Abaqus to capture both global stress–strain responses and localized damage evolution. Uniaxial compression tests on thermally exposed cylinders provided residual strength data and failure observations for model calibration and validation. Results demonstrated a distinct two-stage degradation regime: moderate stiffness and strength reduction up to ~400°C, followed by sharp deterioration beyond 500°C–600°C, with residual capacity at… More >

Pengwei Guo¹, Xiao Tan^2,3,*, Yiming Liu⁴

Structural Durability & Health Monitoring, Vol.20, No.1, 2026, DOI:10.32604/sdhm.2025.071317 - 08 January 2026

Abstract Crack detection accuracy in computer vision is often constrained by limited annotated datasets. Although Generative Adversarial Networks (GANs) have been applied for data augmentation, they frequently introduce blurs and artifacts. To address this challenge, this study leverages Denoising Diffusion Probabilistic Models (DDPMs) to generate high-quality synthetic crack images, enriching the training set with diverse and structurally consistent samples that enhance the crack segmentation. The proposed framework involves a two-stage pipeline: first, DDPMs are used to synthesize high-fidelity crack images that capture fine structural details. Second, these generated samples are combined with real data to train… More >

Hüseyin Bilgin^*, Bredli Plaku

Structural Durability & Health Monitoring, Vol.20, No.1, 2026, DOI:10.32604/sdhm.2025.071007 - 08 January 2026

Abstract Nonlinear static procedures are widely adopted in structural engineering practice for seismic performance assessment due to their simplicity and computational efficiency. However, their reliability depends heavily on how the nonlinear behaviour of structural components is represented. The recent earthquakes in Albania (2019) and Türkiye (2023) have underscored the need for accurate assessment techniques, particularly for older reinforced concrete buildings with poor detailing. This study quantifies the discrepancies between default and user-defined component modelling in pushover analysis of pre-modern reinforced concrete structures, analysing two representative low- and mid-rise reinforced concrete frame buildings. The lumped plasticity approach… More > Graphic Abstract

Hongcheng Zhao¹, Tong Yang ², Yihui Hu², Fengxiang Guo^2,*

Structural Durability & Health Monitoring, Vol.20, No.1, 2026, DOI:10.32604/sdhm.2025.068987 - 08 January 2026

Abstract With the rapid development of transportation infrastructure, ensuring road safety through timely and accurate highway inspection has become increasingly critical. Traditional manual inspection methods are not only time-consuming and labor-intensive, but they also struggle to provide consistent, high-precision detection and real-time monitoring of pavement surface defects. To overcome these limitations, we propose an Automatic Recognition of Pavement Defect (ARPD) algorithm, which leverages unmanned aerial vehicle (UAV)-based aerial imagery to automate the inspection process. The ARPD framework incorporates a backbone network based on the Selective State Space Model (S³M), which is designed to capture long-range temporal dependencies.… More >

Sarra B. Shakartalla^1,2,3, Iman M. Talaat^1,2,4,*, Nival Ali¹, Shahenaz S. Salih^1,5, Zainab M. Al Shareef^1,2, Noura Alkhayyal⁶, Riyad Bendardaf^2,7,*, Sameh S. M. Soliman^1,8,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070808 - 30 December 2025

Abstract Objectives: Breast cancer (BC) is the leading cause of cancer-related mortality in women, largely due to metastasis. This study aims to explore the role of purine nucleoside phosphorylase (PNP), a key enzyme in purine metabolism, in the aggressiveness and metastatic behavior of BC. Methods: A comprehensive analysis was performed using in silico transcriptomic data (n = 2509 patients), immunohistochemical profiling of BC tissues (n = 103), and validation through western blotting in multiple BC cell lines. Gene expression and survival analyses were conducted using Tumor Immune Estimation Resource (TIMER), Gene Expression Profiling Interactive Analysis 2 (GEPIA2), and… More >

Kai Gui^1,#, Tianyi Yang^1,#, Chengying Xiong¹, Yue Wang¹, Zhiqiang He¹, Wuxian Li^2,3,*, Min Tang^1,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.070143 - 30 December 2025

Abstract Objectives: The mechanism by which specific tumor subsets in colorectal cancer (CRC) use alternative metabolic pathways, particularly those modulated by hypoxia and fructose, to alter the tumor microenvironment (TME) remains unclear. This study aimed to identify these malignant subpopulations and characterize their intercellular signaling networks and spatial organization through an integrative multi-omics approach. Methods: Leveraging bulk datasets, single-cell RNA sequencing, and integrative spatial transcriptomics, we developed a prognostic model based on hypoxia-and fructose metabolism-related genes (HFGs) to delineate tumor cell subpopulations and their intercellular signaling networks. Results: We identified a specific subset of stanniocalcin-2 positive (STC2+)… More > Graphic Abstract

Jing Cai^1,#, Haoyun Zhu^1,#, Weiling Guo¹, Ting Huang¹, Pangzhou Chen^1,2, Wen Zhou¹, Ziyun Guan^1,3,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.069902 - 30 December 2025

Abstract Background: Therapeutic responses of breast cancer vary among patients and lead to drug resistance and recurrence due to the heterogeneity. Current preclinical models, however, are inadequate for predicting individual patient responses towards different drugs. This study aimed to investigate the patient-derived breast cancer culture models for drug sensitivity evaluations. Methods: Tumor and adjacent tissues from female breast cancer patients were collected during surgery. Patient-derived breast cancer cells were cultured using the conditional reprogramming technique to establish 2D models. The obtained patient-derived conditional reprogramming breast cancer (CRBC) cells were subsequently embedded in alginate-gelatin methacryloyl hydrogel microspheres… More >

Yimin Liu^1,#, Bin Liu^2,3,4,#, Huabin Gao¹, Jinlong Wang⁵, Jingya Duan¹, Xiaolan Huang¹, Yuexi Liu¹, Ying Huang¹, Wenjing Liao¹, Ruonan Li^1,*, Hua Linghu^1,*

Oncology Research, Vol.34, No.1, 2026, DOI:10.32604/or.2025.069007 - 30 December 2025

Abstract Objectives: High-grade serous ovarian cancer (HGSOC), the most common subtype of epithelial ovarian cancer (EOC), exhibits a mesenchymal phenotype characterized by fibrotic stroma and poor prognosis. Human epididymis protein 4 (HE4), a key diagnostic biomarker for ovarian cancer, is involved in fibrotic processes in several non-malignant diseases. Given the clinical significance of stromal fibrosis in HGSOC and the potential link between HE4 and fibrosis, this study aimed to investigate the role of HE4 in the formation of stromal fibrosis in HGSOC. Methods: A total of 126 patients with gynecological conditions were included and divided into… More > Graphic Abstract

Mohammed Benamara^1,2, Boumediene Touati³, Said Bennaceur⁴, Bendjillali Ridha Ilyas^5,*

Energy Engineering, Vol.123, No.1, 2026, DOI:10.32604/ee.2025.072641 - 27 December 2025

Abstract This study explores the thin-layer convective solar drying of Marrubium vulgare L. leaves under conditions typical of sun-rich semi-arid climates. Drying experiments were conducted at three inlet-air temperatures (40°C, 50°C, 60°C) and two air velocities (1.5 and 2.5 m·s⁻¹) using an indirect solar dryer with auxiliary temperature control. Moisture-ratio data were fitted with eight widely used thin-layer models and evaluated using correlation coefficient (r), root-mean-square error (RMSE), and Akaike information criterion (AIC). A complementary heat-transfer analysis based on Reynolds and Prandtl numbers with appropriate Nusselt correlations was used to relate flow regime to drying performance, and an… More > Graphic Abstract