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    ABSTRACT

    The Effect of Short-Term Exposure in PM0.1 on Cardiac Remodeling and Dysfunction in Myocardial Infraction Mice

    Yufan Huang1, Pei Niu2, Li Li2, Yunlong Huo3,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 47-47, 2019, DOI:10.32604/mcb.2019.05726

    Abstract We aimed to illustrate the association between short-term exposure PM0.1 and heart failure in myocardial infarction (MI) mice. Six-week-old ICR mice were divided into three groups randomly: sham group, MI group and MI exposure group, 12 mice in each group. LAD ligation operation was performed in MI group and MI exposure group. After postoperative two weeks MI exposure mice were put into ventilation chamber which filled with 500 ug/m3 PM0.1 for 6 hours per day, while MI group mice and sham group mice were cultivated in normal environment. After exposure 8 weeks, we use Vevo 2100 machine to acquire heart… More >

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