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  • Open Access

    ARTICLE

    Effect of Organic Waste and Inorganic Additives on Organic Matter Transformation and Mineral Availability in Composting Green Waste

    Abderrahim Boutasknit1,2,3, Mohamed Anli3, Rachid Lahlali4,*, Abdelilah Meddich2,3,5,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.9, pp. 2227-2249, 2024, DOI:10.32604/phyton.2024.055629 - 30 September 2024

    Abstract Applying organic waste and inorganic additives during composting can be an effective and easy-to-control strategy for optimizing humification, maturation, and the availability of essential mineral elements in compost. In this respect, this study aims to evaluate the effect of organic (olive-mill waste and horse manure) and inorganic (phosphogypsum) additives on the evolution of maturity indices, aromatic compounds, and nutrient availability during composting. Four mixtures [horse manure + green waste (M1), olive-mill + green waste (M2), sewage-sludge + phos-phogypsum + green waste (M3), and green waste (M4)] were carried out. Physicochemical (temperature, pH, phosphorus, nitrogen, and… More >

  • Open Access

    ARTICLE

    Drought Stress Alleviation in Chenopodium quinoa through Synergistic Effect of Silicon and Molybdenum via Triggering of SNF1-Associated Protein Kinase 2 Signaling Mechanism

    Asmat Askar1,#, Humaira Gul1,#, Mamoona Rauf1, Muhammad Arif2, Bokyung Lee3, Sajid Ali4,*, Abdulwahed Fahad Alrefaei5, Mikhlid H. Almutairi5, Zahid Ali Butt6, Ho-Youn Kim7, Muhammad Hamayun1,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.9, pp. 2455-2478, 2024, DOI:10.32604/phyton.2024.054508 - 30 September 2024

    Abstract Drought stress negatively impacts agricultural crop yields. By using mineral fertilizers and chemical regulators to encourage plant development and growth, its impact can be mitigated. The current study revealed that exogenous silicon (Si) (potassium silicate; K2Si2O5 at 1000 ppm) and molybdenum (Mo) (ammonium molybdate; (NH4)6Mo7O24•4H2O at 100 ppm) improved drought tolerance in quinoa (Chenopodium quinoa Willd). The research was conducted in a randomized complete block design with three biological replicates. The treatments comprised T0 (control, water spray), T4 (drought stress), and T1, T2, T3, T5, T6, and T7, i.e., foliar applications of silicon and molybdenum solutions individually… More >

  • Open Access

    REVIEW

    Spliceosome-mediated RNA trans-splicing: a strategy for Huntington’s disease gene therapy

    QINGYANG ZHANG, SHUXIAN HUANG, DAN WENG*

    BIOCELL, Vol.48, No.10, pp. 1443-1453, 2024, DOI:10.32604/biocell.2024.053794 - 02 October 2024

    Abstract Huntington’s disease (HD) is a debilitating neurodegenerative disorder caused by an abnormal expansion of CAG repeats (Cytosine, Adenine, Guanine) in the huntingtin gene (HTT). This mutation leads to the production of a mutant huntingtin protein, resulting in neuronal dysfunction and cell death. Current treatments primarily focus on symptomatic relief and do not address the underlying genetic cause. This review explores spliceosome-mediated RNA trans-splicing (SMaRT) therapy as an innovative and potential approach for HD treatment. SMaRT leverages the cell’s natural splicing machinery to correct mutant mRNA, thereby reducing toxic protein levels while restoring functional protein production. We More >

  • Open Access

    REVIEW

    Pioneering a new era in Parkinson’s disease management through adipose-derived mesenchymal stem cell therapy

    MOHAMMAD-SADEGH LOTFI, FATEMEH B. RASSOULI*

    BIOCELL, Vol.48, No.10, pp. 1419-1428, 2024, DOI:10.32604/biocell.2024.053597 - 02 October 2024

    Abstract Parkinson’s disease (PD) is one of the fastest-growing neurodegenerative disorders worldwide. So far, PD treatments only offer little clinical relief and cannot reverse or stop the disease progression. Stem cell (SC) therapy is a rapidly evolving technology that holds significant promise for enhancing current therapeutic approaches. Adipose-derived mesenchymal SCs (AD-MSCs) have many features such as easy harvest with minimal invasive techniques, high plasticity, non-immunogenicity, and no ethical issues, which have made them suitable choices for clinical applications in regenerative research. AD-MSCs are ideal tools to treat PD, as they have the potential to differentiate into… More >

  • Open Access

    REVIEW

    Neural stem cell-derived exosomes: a cell-free transplant for potential cure of neurological diseases

    JIAJUN HUANG1,#, WEI WANG1,#, WENTONG LIN2, HENGSEN CAI3, ZHIHAN ZHU1, WAQAS AHMED4, QIANKUN ZHANG1, JIALE LIU1, YIFAN ZHANG1, RONG LI1, ZHINUO LI1, AHSAN ALI KHAN5, DENG LU3, YONG HU6, LUKUI CHEN1,*

    BIOCELL, Vol.48, No.10, pp. 1405-1418, 2024, DOI:10.32604/biocell.2024.053148 - 02 October 2024

    Abstract Degeneration and death of nerve cells are inevitable with the occurrence and progression of nervous system disorders. Researchers transplanted neural stem cells into relevant areas, trying to solve the difficulty of neural cell loss by differentiating neural stem cells into various nerve cells. In recent years, however, studies have shown that transplanted neural stem cells help neural tissues regenerate and return to normal through paracrine action rather than just replacing cells. Exosomes are essential paracrine mediators, which can participate in cell communication through substance transmission. In this regard, this review mainly discusses the current research More >

  • Open Access

    ARTICLE

    Advancements in Numerical Solutions: Fractal Runge-Kutta Approach to Model Time-Dependent MHD Newtonian Fluid with Rescaled Viscosity on Riga Plate

    Muhammad Shoaib Arif1,2,*, Kamaleldin Abodayeh1, Yasir Nawaz2

    CMES-Computer Modeling in Engineering & Sciences, Vol.141, No.2, pp. 1213-1241, 2024, DOI:10.32604/cmes.2024.054819 - 27 September 2024

    Abstract Fractal time-dependent issues in fluid dynamics provide a distinct difficulty in numerical analysis due to their complex characteristics, necessitating specialized computing techniques for precise and economical solutions. This study presents an innovative computational approach to tackle these difficulties. The main focus is applying the Fractal Runge-Kutta Method to model the time-dependent magnetohydrodynamic (MHD) Newtonian fluid with rescaled viscosity flow on Riga plates. An efficient computational scheme is proposed for handling fractal time-dependent problems in flow phenomena. The scheme is comprised of three stages and constructed using three different time levels. The stability of the scheme… More >

  • Open Access

    ARTICLE

    Robust Particle Swarm Optimization Algorithm for Modeling the Effect of Oxides Thermal Properties on AMIG 304L Stainless Steel Welds

    Rachid Djoudjou1,*, Abdeljlil Chihaoui Hedhibi3, Kamel Touileb1, Abousoufiane Ouis1, Sahbi Boubaker2, Hani Said Abdo4,5

    CMES-Computer Modeling in Engineering & Sciences, Vol.141, No.2, pp. 1809-1825, 2024, DOI:10.32604/cmes.2024.053621 - 27 September 2024

    Abstract There are several advantages to the MIG (Metal Inert Gas) process, which explains its increased use in various welding sectors, such as automotive, marine, and construction. A variant of the MIG process, where the same equipment is employed except for the deposition of a thin layer of flux before the welding operation, is the AMIG (Activated Metal Inert Gas) technique. This study focuses on investigating the impact of physical properties of individual metallic oxide fluxes for 304L stainless steel welding joint morphology and to what extent it can help determine a relationship among weld depth… More >

  • Open Access

    ARTICLE

    Optimal Cyber Attack Strategy Using Reinforcement Learning Based on Common Vulnerability Scoring System

    Bum-Sok Kim1, Hye-Won Suk1, Yong-Hoon Choi2, Dae-Sung Moon3, Min-Suk Kim2,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.141, No.2, pp. 1551-1574, 2024, DOI:10.32604/cmes.2024.052375 - 27 September 2024

    Abstract Currently, cybersecurity threats such as data breaches and phishing have been on the rise due to the many different attack strategies of cyber attackers, significantly increasing risks to individuals and organizations. Traditional security technologies such as intrusion detection have been developed to respond to these cyber threats. Recently, advanced integrated cybersecurity that incorporates Artificial Intelligence has been the focus. In this paper, we propose a response strategy using a reinforcement-learning-based cyber-attack-defense simulation tool to address continuously evolving cyber threats. Additionally, we have implemented an effective reinforcement-learning-based cyber-attack scenario using Cyber Battle Simulation, which is a… More >

  • Open Access

    ARTICLE

    A Two-Stage Scenario-Based Robust Optimization Model and a Column-Row Generation Method for Integrated Aircraft Maintenance-Routing and Crew Rostering

    Khalilallah Memarzadeh1, Hamed Kazemipoor1,*, Mohammad Fallah1, Babak Farhang Moghaddam2

    CMES-Computer Modeling in Engineering & Sciences, Vol.141, No.2, pp. 1275-1304, 2024, DOI:10.32604/cmes.2024.050306 - 27 September 2024

    Abstract Motivated by a critical issue of airline planning process, this paper addresses a new two-stage scenario-based robust optimization in operational airline planning to cope with uncertainty and possible flight disruptions. Following the route network scheme and generated flight timetables, aircraft maintenance routing and crew scheduling are critical factors in airline planning and operations cost management. This study considers the simultaneous assignment of aircraft fleet and crew to the scheduled flight while satisfying a set of operational constraints, rules, and regulations. Considering multiple locations for airline maintenance and crew bases, we solve the problem of integrated… More > Graphic Abstract

    A Two-Stage Scenario-Based Robust Optimization Model and a Column-Row Generation Method for Integrated Aircraft Maintenance-Routing and Crew Rostering

  • Open Access

    ARTICLE

    Reduction Discoloration of Reactive Dyed Cotton Waste and Chemical Recycling via Ionic Liquid

    Aline Ferreira Knihs, Larissa Klen Aragão, Miguel Angelo Granato, Andrea Cristiane Krause Bierhalz*, Rita de Cassia Siqueira Curto Valle

    Journal of Renewable Materials, Vol.12, No.9, pp. 1557-1571, 2024, DOI:10.32604/jrm.2024.052963 - 25 September 2024

    Abstract The textile industry generates large volumes of waste throughout its production process. Most of this waste is colored, therefore, discoloration is an important step toward recycling and reusing this waste. This study focused on the chemical reductive discoloration of textile waste composed of cotton dyed with reactive dye. The experimental design demonstrated the significant influence of the concentration of reducing agent and time of reaction on the degree of whiteness of the cotton fibers. The concentration of the alkaline agent was not significant in the process. The optimization of the reaction conditions lead to Berger… More > Graphic Abstract

    Reduction Discoloration of Reactive Dyed Cotton Waste and Chemical Recycling via Ionic Liquid

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