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Search Results (4)
  • Open Access

    ARTICLE

    Hepatitis B virus X protein-mediated upregulation of miR-221 activates the CXCL12-CXCR4 axis to promote NKT cells in HBV-related hepatocellular carcinoma

    YUE CAO, LIN HU, YISHU TANG*

    BIOCELL, Vol.47, No.7, pp. 1537-1548, 2023, DOI:10.32604/biocell.2023.027205

    Abstract Backgrounds: Both hepatitis B virus X protein (HBx) and microRNA-221 (miR-221) have been implicated in the development of hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC). The present study demonstrates that HBx promotes HCC cell proliferation via the C-X-C motif chemokine ligand 12-C-X-C chemokine receptor type 4 (CXCL12-CXCR4) axis. We predict that HBx/miR-221-mediated CXCL12/CXCR4 signaling induces NKT cells to promote HBV-related HCC. Methods: After miR-221 mimic, miR-221 mimic negative control, miR-221 inhibitor, miR-221 inhibitor negative control were transfected into cells, the expression of CXCL12 and miR-221 was detected by qPCR and western blot. Then we constructed a stable HBV-HCC cell line.… More >

  • Open Access

    ARTICLE

    Temporal variation of phytoplankton populations in response to granular and liquid fertilizers

    Tizkar B1, A Seidavi2, M Sudagar3, JT Ponce-Palafox4

    Phyton-International Journal of Experimental Botany, Vol.83, pp. 109-116, 2014, DOI:10.32604/phyton.2014.83.109

    Abstract The aim of this study was to determine the effect of a granular or liquid fertilizer on the temporal variation of phytoplankton. Enrichment of the pond water with nitrogen and phosphorus resulted in an increased gross photosynthesis and biomass of the dominant algal species. Nutrient concentrations and dilution rates can determine the temporal variation in phytoplankton abundance and primary production. The variation may be largely maintained by nutrient regeneration or turnover from different forms. More >

  • Open Access

    ARTICLE

    Composition and abundance of phytoplankton ın relation to physical and chemical variables in The Kars River, Turkey

    Özbay H

    Phyton-International Journal of Experimental Botany, Vol.80, pp. 85-92, 2011, DOI:10.32604/phyton.2011.80.085

    Abstract The phytoplankton of the Kars River was studied from May to October 2005 at five sampling stations. Sixty-six phytoplankton taxa were determined, consisting of Cyanophyta (9), Chlorophyta (25), Euglenophyta (18), Bacillariophyta (7), Cryptophyta (3), Dinophyta (1) and Chrysophyta (3). Total phytoplankton density increased from May to July and then decreased until October. The dominant phytoplankton group was Cyanophyta (36.5 - 64.4%) for most of the study period, followed by Bacillariophyta (20.4 – 38.7%) and Chlorophyta (20.9 – 28.9%). Temperature, pH and dissolved oxygen ranged from 9.6 °C to 21.6 °C; 7.6 to 8.0, and 5.9 to 7.4 mg/L, respectively. Chlorophyl… More >

  • Open Access

    REVIEW

    Oxidative effects of the harmful algal blooms on primary organisms of the food web

    Joaquin Cabrera1,2, Paula Mariela González1,2, Susana Puntarulo1,2

    BIOCELL, Vol.43, No.2, pp. 41-50, 2019, DOI:10.32604/biocell.2019.06163

    Abstract Degraded water quality from nutrient pollution, physical, biological, and other chemical factors contributes to the development and persistence of many harmful algal blooms (HABs). The complex dynamics of the HABs is a challenge to marine ecosystems for the toxic effects reported. The consequences include fish, bird, and mammal mortality, respiratory or digestive tract problems, memory loss, seizures, lesions and skin irritation in many organisms. This review is intended to briefly summarize the recent reported information on harmful marine toxin deleterious effects over the primary organisms of the food web, namely algae, zooplankton and invertebrates. Special focus is made on oxidative… More >

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