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  • Open Access

    ARTICLE

    YOLO-O2E: A Variant YOLO Model for Anomalous Rail Fastening Detection

    Zhuhong Chu1, Jianxun Zhang1,*, Chengdong Wang2, Changhui Yang3

    CMC-Computers, Materials & Continua, Vol.80, No.1, pp. 1143-1161, 2024, DOI:10.32604/cmc.2024.052269

    Abstract Rail fasteners are a crucial component of the railway transportation safety system. These fasteners, distinguished by their high length-to-width ratio, frequently encounter elevated failure rates, necessitating manual inspection and maintenance. Manual inspection not only consumes time but also poses the risk of potential oversights. With the advancement of deep learning technology in rail fasteners, challenges such as the complex background of rail fasteners and the similarity in their states are addressed. We have proposed an efficient and high-precision rail fastener detection algorithm, named YOLO-O2E (you only look once-O2E). Firstly, we propose the EFOV (Enhanced Field… More >

  • Open Access

    ARTICLE

    Federated Network Intelligence Orchestration for Scalable and Automated FL-Based Anomaly Detection in B5G Networks

    Pablo Fernández Saura1,*, José M. Bernabé Murcia1, Emilio García de la Calera Molina1, Alejandro Molina Zarca2, Jorge Bernal Bernabé1, Antonio F. Skarmeta Gómez1

    CMC-Computers, Materials & Continua, Vol.80, No.1, pp. 163-193, 2024, DOI:10.32604/cmc.2024.051307

    Abstract The management of network intelligence in Beyond 5G (B5G) networks encompasses the complex challenges of scalability, dynamicity, interoperability, privacy, and security. These are essential steps towards achieving the realization of truly ubiquitous Artificial Intelligence (AI)-based analytics, empowering seamless integration across the entire Continuum (Edge, Fog, Core, Cloud). This paper introduces a Federated Network Intelligence Orchestration approach aimed at scalable and automated Federated Learning (FL)-based anomaly detection in B5G networks. By leveraging a horizontal Federated learning approach based on the FedAvg aggregation algorithm, which employs a deep autoencoder model trained on non-anomalous traffic samples to recognize… More >

  • Open Access

    ARTICLE

    Optimized Binary Neural Networks for Road Anomaly Detection: A TinyML Approach on Edge Devices

    Amna Khatoon1, Weixing Wang1,*, Asad Ullah2, Limin Li3,*, Mengfei Wang1

    CMC-Computers, Materials & Continua, Vol.80, No.1, pp. 527-546, 2024, DOI:10.32604/cmc.2024.051147

    Abstract Integrating Tiny Machine Learning (TinyML) with edge computing in remotely sensed images enhances the capabilities of road anomaly detection on a broader level. Constrained devices efficiently implement a Binary Neural Network (BNN) for road feature extraction, utilizing quantization and compression through a pruning strategy. The modifications resulted in a 28-fold decrease in memory usage and a 25% enhancement in inference speed while only experiencing a 2.5% decrease in accuracy. It showcases its superiority over conventional detection algorithms in different road image scenarios. Although constrained by computer resources and training datasets, our results indicate opportunities for More >

  • Open Access

    RETRACTION

    Retraction: Knockdown of Gab1 Inhibits Cellular Proliferation, Migration, and Invasion in Human Oral Squamous Carcinoma Cells

    Oncology Research Editorial Office

    Oncology Research, Vol.32, No.8, pp. 1387-1387, 2024, DOI:10.32604/or.2024.055039

    Abstract This article has no abstract. More >

  • Open Access

    RETRACTION

    Retraction: Knockdown of Urothelial Carcinoma-Associated 1 Suppressed Cell Growth and Migration Through Regulating miR-301a and CXCR4 in Osteosarcoma MHCC97 Cells

    Oncology Research Editorial Office

    Oncology Research, Vol.32, No.8, pp. 1381-1381, 2024, DOI:10.32604/or.2024.055035

    Abstract This article has no abstract. More >

  • Open Access

    REVIEW

    Biological characteristics and clinical management of uveal and conjunctival melanoma

    SNJEŽANA KAŠTELAN1,2, ANA DIDOVIĆ PAVIČIĆ3, DARIA PAŠALIĆ4, TAMARA NIKUŠEVA-MARTIĆ5, SAMIR ČANOVIĆ3,7, PETRA KOVAČEVIĆ1,6,*, SUZANA KONJEVODA3,7

    Oncology Research, Vol.32, No.8, pp. 1265-1285, 2024, DOI:10.32604/or.2024.048437

    Abstract Uveal and conjunctival melanomas are relatively rare tumors; nonetheless, they pose a significant risk of mortality for a large number of affected individuals. The pathogenesis of melanoma at different sites is very similar, however, the prognosis for patients with ocular melanoma remains unfavourable, primarily due to its distinctive genetic profile and tumor microenvironment. Regardless of considerable advances in understanding the genetic characteristics and biological behaviour, the treatment of uveal and conjunctival melanoma remains a formidable challenge. To enhance the prospect of success, collaborative efforts involving medical professionals and researchers in the fields of ocular biology… More > Graphic Abstract

    Biological characteristics and clinical management of uveal and conjunctival melanoma

  • Open Access

    ARTICLE

    Fibroblast activation protein (FAP) as a prognostic biomarker in multiple tumors and its therapeutic potential in head and neck squamous cell carcinoma

    RUIFANG LI1, XINRONG NAN2,*, MING LI3,*, OMAR RAHHAL3

    Oncology Research, Vol.32, No.8, pp. 1323-1334, 2024, DOI:10.32604/or.2024.046965

    Abstract Background: Fibroblast activation protein (FAP), a cell surface serine protease, plays roles in tumor invasion and immune regulation. However, there is currently no pan-cancer analysis of FAP. Objective: We aimed to assess the pan-cancer expression profile of FAP, its molecular function, and its potential role in head and neck squamous cell carcinoma (HNSC). Methods: We analyzed gene expression, survival status, immune infiltration, and molecular functional pathways of FAP in The Cancer Genome Atlas (TCGA) and Genotype Tissue Expression (GTEx) tumors. Furthermore, to elucidate the role of FAP in HNSC, we performed proliferation, migration, and invasion assays… More >

  • Open Access

    ARTICLE

    Tmem39b promotes tumor progression and sorafenib resistance by inhibiting ferroptosis in hepatocellular carcinoma

    MING ZHUANG, XUE ZHANG, LU LI, LIMING WEN, JIAMIN QIN*

    Oncology Research, Vol.32, No.8, pp. 1347-1357, 2024, DOI:10.32604/or.2024.046170

    Abstract Hepatocellular carcinoma (HCC) poses a significant threat to human health. Resistance to sorafenib in the chemotherapy of HCC is a common and significant issue that profoundly impacts clinical treatment. While several members of the transmembrane (TMEM) protein family have been implicated in the occurrence and progression of HCC, the association between TMEM39b and HCC remains unexplored. This study revealed a significant overexpression of TMEM39b in HCC, which correlated with a poor prognosis. Subsequent investigation revealed that RAS-selective lethal 3 (RSL3) induced pronounced ferroptosis in HCC, and knocking down the expression of TMEM39b significantly decreased its More >

  • Open Access

    ARTICLE

    LSTM Based Neural Network Model for Anomaly Event Detection in Care-Independent Smart Homes

    Brij B. Gupta1,2,3,*, Akshat Gaurav4, Razaz Waheeb Attar5, Varsha Arya6,7, Ahmed Alhomoud8, Kwok Tai Chui9

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.3, pp. 2689-2706, 2024, DOI:10.32604/cmes.2024.050825

    Abstract This study introduces a long-short-term memory (LSTM)-based neural network model developed for detecting anomaly events in care-independent smart homes, focusing on the critical application of elderly fall detection. It balances the dataset using the Synthetic Minority Over-sampling Technique (SMOTE), effectively neutralizing bias to address the challenge of unbalanced datasets prevalent in time-series classification tasks. The proposed LSTM model is trained on the enriched dataset, capturing the temporal dependencies essential for anomaly recognition. The model demonstrated a significant improvement in anomaly detection, with an accuracy of 84%. The results, detailed in the comprehensive classification and confusion More >

  • Open Access

    ARTICLE

    A Novel Graph Structure Learning Based Semi-Supervised Framework for Anomaly Identification in Fluctuating IoT Environment

    Weijian Song1,, Xi Li1,, Peng Chen1,*, Juan Chen1, Jianhua Ren2, Yunni Xia3,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.140, No.3, pp. 3001-3016, 2024, DOI:10.32604/cmes.2024.048563

    Abstract With the rapid development of Internet of Things (IoT) technology, IoT systems have been widely applied in healthcare, transportation, home, and other fields. However, with the continuous expansion of the scale and increasing complexity of IoT systems, the stability and security issues of IoT systems have become increasingly prominent. Thus, it is crucial to detect anomalies in the collected IoT time series from various sensors. Recently, deep learning models have been leveraged for IoT anomaly detection. However, owing to the challenges associated with data labeling, most IoT anomaly detection methods resort to unsupervised learning techniques.… More >

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