Manas Ranjan Prusty1, Rishi Dinesh2, Hariket Sukesh Kumar Sheth2, Alapati Lakshmi Viswanath2, Sandeep Kumar Satapathy2,3,*
CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3077-3094, 2023, DOI:10.32604/cmc.2023.042718
Abstract This paper presents a novel computerized technique for the segmentation of nuclei in hematoxylin and eosin (H&E) stained histopathology images. The purpose of this study is to overcome the challenges faced in automated nuclei segmentation due to the diversity of nuclei structures that arise from differences in tissue types and staining protocols, as well as the segmentation of variable-sized and overlapping nuclei. To this extent, the approach proposed in this study uses an ensemble of the UNet architecture with various Convolutional Neural Networks (CNN) architectures as encoder backbones, along with stain normalization and test time augmentation, to improve segmentation accuracy.… More >
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