YIXIAN YOU^1,3,#, YIHUNG LEE^2,#, YUSHIN HU², YOUHUI XU³, JOUCHEN CHEN², WEI JIANG¹, CHANGHAI LIU¹, ENQIANG CHEN¹, HONG TANG¹, HUA ZHANG^4,*, DONGBO WU^1,*

BIOCELL, Vol.49, No.1, pp. 45-59, 2025, DOI:10.32604/biocell.2024.057259 - 24 January 2025

Abstract With organ transplantation facing many dilemmas, tissue and organ regeneration as an alternative has bright prospects. In regenerative medicine, Three-dimensional (3D) printing technology and stem cells has been widely applied to the treatment of diseases related to tissue or organ replacement in dentistry, respectively. However, there are very few studies on the combination of the two, and even fewer clinical studies have been reported in dentistry. In this review, the current oral tissue engineering in vivo and in vitro based on 3D printing and stem cell technology will be summarized, and the discussion on the development… More >

MENGYING MAO^1,2,3,#, TING DONG^1,2,3,#, YANJING LIANG^3,4, KEYONG YUAN^1,2,3, QIAOQIAO JIN^1,2,3, PENGFEI ZHANG^1,2,3, ZHENGWEI HUANG^1,2,3,*

BIOCELL, Vol.47, No.10, pp. 2187-2193, 2023, DOI:10.32604/biocell.2023.042357 - 08 November 2023

Abstract The oral microbiota is a vital part of the human microbiota that functions in various physiological processes and is highly relevant to cancers and other diseases. With the alterations of host immune competence, the homeostatic balance existing between the oral microbiota and host may be disturbed and result in the development of diseases. Numerous observations have suggested that small RNAs are key regulators of bacterial pathogenesis and bacteria-host interactions. Further, bacterial small RNAs are considered to be promising biomarkers for the development of novel, and efficacious therapies for oral dysbiosis. Mechanistic insights into how oral More > Graphic Abstract