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  • Open Access

    ARTICLE

    Experimental Study on the Axial Compression Performance of Bamboo Scrimber Columns Embedded with Steel Reinforcing Bars

    Xueyan Lin1,#, Mingtao Wu2,#, Guodong Li1,*, Nan Guo3, Lidan Mei1

    Structural Durability & Health Monitoring, Vol.18, No.6, pp. 805-833, 2024, DOI:10.32604/sdhm.2024.051033

    Abstract In this paper, a new type of bamboo scrimber column embedded with steel bars (rebars) was proposed, and the compression performance was improved by pre-embedding rebars during the preparation of the columns. The effects of the slenderness ratio and the reinforcement ratio on the axial compression performance of reinforced bamboo scrimber columns were studied by axial compression tests on 28 specimens. The results showed that the increase in the slenderness ratio had a significant negative effect on the axial compression performance of the columns. When the slenderness ratio increased from 19.63 to 51.96, the failure… More >

  • Open Access

    RETRACTION

    Retraction: miR-203 suppresses bladder cancer cell growth and targets twist1

    Oncology Research Editorial Office

    Oncology Research, Vol.32, No.10, pp. 1693-1694, 2024, DOI:10.32604/or.2024.056909

    Abstract This article has no abstract. More >

  • Open Access

    RETRACTION

    Retraction: MicroRNA-520b suppresses proliferation, migration, and invasion of spinal osteosarcoma cells via downregulation of frizzled-8

    Oncology Research Editorial Office

    Oncology Research, Vol.32, No.10, pp. 1687-1688, 2024, DOI:10.32604/or.2024.056903

    Abstract This article has no abstract. More >

  • Open Access

    RETRACTION

    Retraction: Function of miR-152 as a tumor suppressor in human breast cancer by targeting PIK3CA

    Oncology Research Editorial Office

    Oncology Research, Vol.32, No.10, pp. 1675-1676, 2024, DOI:10.32604/or.2024.056889

    Abstract This article has no abstract. More >

  • Open Access

    ARTICLE

    Exosomal microRNA let-7c-5p enhances cell malignant characteristics by inhibiting TAGLN in oral cancer

    YI LI1, TIANYI WANG1, HAORAN DING1, SHIYONG ZHUANG1, XIAOBO DAI1, BING YAN1,2,*

    Oncology Research, Vol.32, No.10, pp. 1623-1635, 2024, DOI:10.32604/or.2024.048191

    Abstract Background: Oral cancer, a malignancy that is prevalent worldwide, is often diagnosed at an advanced stage. MicroRNAs (miRNAs) in circulating exosomes have emerged as promising cancer biomarkers. The role of miRNA let-7c-5p in oral cancer remains underexplored, and its potential involvement in tumorigenesis warrants comprehensive investigation. Methods: Serum samples from 30 patients with oral cancer and 20 healthy controls were used to isolate exosomes and quantify their RNA content. Isolation of the exosomes was confirmed through transmission electron microscopy. Quantitative PCR was used to assess the miRNA profiles. The effects of let-7c-5p and TAGLN overexpression… More >

  • Open Access

    ARTICLE

    PD-1+ and TIM-3+ T cells widely express common γ-chain cytokine receptors in multiple myeloma patients, and IL-2, IL-7, IL-15 stimulation up-regulates PD-1 and TIM-3 on T cells

    EGOR V. BATOROV1,2,*, ALISA D. INESHINA2, TATIANA A. ARISTOVA3, VERA V. DENISOVA3, SVETLANA A. SIZIKOVA3, DARIA S. BATOROVA3, GALINA Y. USHAKOVA3, EKATERINA Y. SHEVELA1, ELENA R. CHERNYKH1

    Oncology Research, Vol.32, No.10, pp. 1575-1587, 2024, DOI:10.32604/or.2024.047893

    Abstract Background: Immune checkpoint ligand-receptor interactions appear to be associated with multiple myeloma (MM) progression. Simultaneously, previous studies showed the possibility of PD-1 and TIM-3 expression on T cells upon stimulation with common γ-chain family cytokines in vitro and during homeostatic proliferation. The aim of the present work was to study the impact of homeostatic proliferation on the expansion of certain T cell subsets up-regulating PD-1 and TIM-3 checkpoint molecules. Methods: The expression of CD25, CD122, CD127 common γ-chain cytokine receptors, phosphorylated signal transducer and activator of transcription-5 (pSTAT5) and eomesodermin (EOMES) was comparatively assessed with flow… More >

  • Open Access

    ARTICLE

    The Mediating and Moderating Effects of Family Resilience on the Relationship between Individual Resilience and Depression in Patients with Breast Cancer

    Youqi Jiang1,#, Bing Wu2,#, Jiahui Chen3, Ruyi Jin3, Guangshan Jin3, Minhao Zhang4, Qin Zhou4,*, Aiji Jiang2,*

    Psycho-Oncologie, Vol.18, No.3, pp. 191-200, 2024, DOI:10.32604/po.2024.053942

    Abstract Objective: This study evaluated the effect of resilience on depression among patients with breast cancer from individual and familial perspectives by exploring the mediating and moderating effects of family resilience between individual resilience and depression. Methods: A questionnaire survey was conducted among 337 patients with breast cancer who were admitted to the Oncology Department of Jiangsu Province Hospital. The survey included demographic information, the Connor–Davidson Resilience Scale (CD-RISC), the Family Resilience Assessment Scale (FRAS), and the Chinese version of the Patient Health Questionnaire-9 (PHQ-9) for Depression. The relationship among individual resilience, family resilience, and depression… More >

  • Open Access

    ARTICLE

    FPGA Accelerators for Computing Interatomic Potential-Based Molecular Dynamics Simulation for Gold Nanoparticles: Exploring Different Communication Protocols

    Ankitkumar Patel1, Srivathsan Vasudevan1,*, Satya Bulusu2,*

    CMC-Computers, Materials & Continua, Vol.80, No.3, pp. 3803-3818, 2024, DOI:10.32604/cmc.2024.052851

    Abstract Molecular Dynamics (MD) simulation for computing Interatomic Potential (IAP) is a very important High-Performance Computing (HPC) application. MD simulation on particles of experimental relevance takes huge computation time, despite using an expensive high-end server. Heterogeneous computing, a combination of the Field Programmable Gate Array (FPGA) and a computer, is proposed as a solution to compute MD simulation efficiently. In such heterogeneous computation, communication between FPGA and Computer is necessary. One such MD simulation, explained in the paper, is the (Artificial Neural Network) ANN-based IAP computation of gold (Au147 & Au309) nanoparticles. MD simulation calculates the forces… More >

  • Open Access

    ARTICLE

    Influence of Formulation and Hot-Pressing Conditions on the Performance of Bio-Based Molasses Adhesive for Plywood

    Jajang Sutiawan1, Alifah Syahfitri2, Sukma Surya Kusumah1, Dede Hermawan2,*, Rita Kartika Sari2, Luthfi Hakim3, Efri Mardawati4,5, Muhammad Adly Rahandi Lubis1,4,*

    Journal of Renewable Materials, Vol.12, No.8, pp. 1383-1397, 2024, DOI:10.32604/jrm.2024.052052

    Abstract Molasses can serve as a natural adhesive for plywood and particleboard. However, several disadvantages remain, including lower dimensional stability and low bonding strength compared to other adhesives. Therefore, modifications are needed to use molasses as an adhesive for plywood. This research aims to improve bio-based molasses (MO) adhesive for plywood using citric acid (CA) adhesive. In addition, this research aims to analyze the effect of adding citric acid and to investigate the optimum hot-pressing temperature to produce the best quality plywood. In the first stage, the molasses and citric acid were combined in a ratio… More > Graphic Abstract

    Influence of Formulation and Hot-Pressing Conditions on the Performance of Bio-Based Molasses Adhesive for Plywood

  • Open Access

    REVIEW

    The role of tazarotene-induced gene 1 in carcinogenesis: is it a tumor suppressor gene or an oncogene?

    CHUN-HUA WANG1,2, LU-KAI WANG3, RONG-YAUN SHYU4, FU-MING TSAI5,*

    BIOCELL, Vol.48, No.9, pp. 1285-1297, 2024, DOI:10.32604/biocell.2024.053746

    Abstract Tazarotene-induced gene 1 (TIG1) is induced by a derivative of vitamin A and is known to regulate many important biological processes and control the development of cancer. TIG1 is widely expressed in various tissues; yet in many cancer tissues, it is not expressed because of the methylation of its promoter. Additionally, the expression of TIG1 in cancer cells inhibits their growth and invasion, suggesting that TIG1 acts as a tumor suppressor gene. However, in some cancers, poor prognosis is associated with TIG1 expression, indicating its protumor growth characteristics, especially in promoting the invasion of inflammatory breast cancer More >

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