AHMAD SHAHIR MOHAMAD NAZRI, NAZIHAH MOHD YUNUS, MARAHAINI MUSA^*

BIOCELL, Vol.49, No.1, pp. 149-160, 2025, DOI:10.32604/biocell.2024.057352 - 24 January 2025

Abstract Pediatric inflammatory bowel disease (IBD) is a chronic and heterogeneous disease. IBD is commonly classified into Crohn’s disease and ulcerative colitis. It is linked to serious symptoms and complications. The onset of IBD commonly occurs during adolescence. Despite the significant number of cases globally (~5 million), the causes of pediatric IBD, which constitutes 25% of IBD patients, are not yet fully understood. Apart from environmental factors, genetic factors contribute to a higher risk of developing IBD. The predisposition risk of IBD can be investigated using genetic testing. Genetic mechanisms of pediatric IBD are highly complex More >

Soha Rawas¹, Cerine Tafran¹, Duaa AlSaeed², Nadia Al-Ghreimil^2,*

CMC-Computers, Materials & Continua, Vol.81, No.3, pp. 4575-4601, 2024, DOI:10.32604/cmc.2024.055307 - 19 December 2024

Abstract In the rapidly evolving landscape of healthcare, the integration of Artificial Intelligence (AI) and Natural Language Processing (NLP) holds immense promise for revolutionizing data analytics and decision-making processes. Current techniques for personalized medicine, disease diagnosis, treatment recommendations, and resource optimization in the Internet of Medical Things (IoMT) vary widely, including methods such as rule-based systems, machine learning algorithms, and data-driven approaches. However, many of these techniques face limitations in accuracy, scalability, and adaptability to complex clinical scenarios. This study investigates the synergistic potential of AI-driven optimization techniques and NLP applications in the context of the… More >

Natalia Roque^1,#, Diana Matias^2,#, Joana Balça-Silva³, Valéria Pereira Ferrer⁴, Luciana Santos Pessoa¹, Tania Cristina Leite de Sampaio e Spohr^1,5,*

Oncologie, Vol.24, No.3, pp. 371-411, 2022, DOI:10.32604/oncologie.2022.024035 - 19 September 2022

Abstract Cancer is one of the deadliest diseases with a cure far from being found. Despite the extraordinary advances in the therapy approaches, only a few patients respond to treatments. The tumor microenvironment (TME) plays a crucial role in cancer progression by contributing to the chemoresistance. Thus, emerging efforts are being made in nanotechnology research focusing on nanoparticles’ potential role and their application in immune system modulation. Moreover, the omics have contributed to bioengineering and nanotechnology development by elucidating the mechanisms of cancer and specific biomarkers that could be used as new therapeutic targets. Furthermore, the More >