Estela M. MUÑOZ
BIOCELL, Vol.42, No.2, pp. 41-46, 2018, DOI:10.32604/biocell.2018.07011
Abstract Until recently, microglia were mainly known as the resident phagocytes of the brain, i.e. the ‘immunological
warriors’ of the brain. However, extensive knowledge is being accumulated about the functions of microglia beyond
immunity. Nowadays, it is well accepted that microglial cells are highly dynamic and responsive, and that they intervene
in a dual manner in many developmental processes that shape the central nervous system, including neurogenesis,
gliogenesis, spatial patterning, synaptic formation and elimination, and neural circuit establishment and maturation.
The differentiation and the pool of precursor cells were also shown to be under microglia regulation via bidirectional
communication. In this… More >
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