Nursyazwani Mohamad Noor1, Siti Ainor Mohd Yatim1,*, Nur Intan Raihana Ruhaiyem2
CMC-Computers, Materials & Continua, Vol.73, No.3, pp. 4923-4934, 2022, DOI:10.32604/cmc.2022.030414
Abstract In this paper, we present a three-compartment of pharmacokinetics model with irreversible rate constants. The compartment consists of arterial blood, tissues and venous blood. Fick’s principle and the law of mass action were used to develop the model based on the diffusion process. The model is modified into a fractional pharmacokinetics model with the sense of Caputo derivative. The existence and uniqueness of the model are investigated and the positivity of the model is established. The behaviour of the model is investigated by implementing numerical algorithms for the numerical solution of the system of fractional differential equations. MATLAB software is… More >
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