KAI WANG^2,#, FENGTIAN ZHANG^1,3,4,#, CHANGLONG WEN⁵, ZHIHUA HUANG⁶, ZHIHAO HU¹, YUWEN ZHANG¹, FUQIANG HU^2,*, LIJUAN WEN^1,6,*

Oncology Research, Vol.29, No.5, pp. 351-363, 2021, DOI:10.32604/or.2022.025696

Abstract The blood-brain barrier (BBB) is an essential component in regulating and maintaining the homeostatic microenvironment of the central nervous system (CNS). During the occurrence and development of glioblastoma (GBM), BBB is pathologically destroyed with a marked increase in permeability. Due to the obstruction of the BBB, current strategies for GBM therapeutics still obtain a meager success rate and may lead to systemic toxicity. Moreover, chemotherapy could promote pathological BBB functional restoration, which results in significantly reduced intracerebral transport of therapeutic agents during multiple administrations of GBM and the eventual failure of GBM chemotherapy. The effective delivery of intracerebral drugs still… More >

Houneida Attia^1,2,*

Phyton-International Journal of Experimental Botany, Vol.92, No.1, pp. 149-164, 2023, DOI:10.32604/phyton.2022.022363

Abstract Pea is a seed legume. It is rich in cellulose fibre and protein. It is also a significant source of minerals and vitamins. In this paper, we set out to better characterize the physiological responses of Pisum sativum L. to the combined effects of NaCl, 100 mM and gibberellins (GA3). Our analysis revealed that NaCl caused a decrease in growth resulting in a reduction in root elongation, distribution and density, leaf number and leaf area, and a decrease in dry matter of roots and shoots. However, the contribution of GA3 in the salty environment induced an increase in these different… More >

Yajie Liu, Linlin Fang, Wenna Zhao, Chunxue Yang^*

Phyton-International Journal of Experimental Botany, Vol.92, No.1, pp. 55-69, 2023, DOI:10.32604/phyton.2022.022159

Abstract Arbuscular mycorrhizal (AM) fungi distribute widely in natural habits and play a variety of ecological functions. In order to test the physiological response to salt stress mediated by different AM fungi, Viola prionantha was selected as the host, the dominant AM fungus in the rhizosphere of V. philippica growing in Songnen saline-alkali grassland, Rhizophagus irregularis, and their mixtures were used as inoculants, and NaCl stress was applied after the roots were colonized. The results showed that V. philippica could be colonized by AM fungi in the field and the colonization rate ranged from 73.33% to 96.67%, and Claroideoglomus etunicatum was… More >

Yan Wan^1,#, Yuan Liang^1,#, Xuxiao Gong^1,#, Jianyong Ouyang¹, Jingwei Huang², Xiaoyong Wu¹, Qi Wu¹, Changying Liu¹, Xueling Ye¹, Xiaoning Cao³, Gang Zhao¹, Liang Zou^1,*, Dabing Xiang^1,*

Phyton-International Journal of Experimental Botany, Vol.92, No.1, pp. 35-54, 2023, DOI:10.32604/phyton.2022.021698

Abstract Tartary buckwheat (Fagopyrum tataricum) is an important pseudocereal feed crop with medicinal and nutritional value. Drought is one of the main causes of reduced growth and yield in these plants. We investigated the growth, physiological, and metabolic responses of the widely promoted Tartary buckwheat variety Chuan Qiao No. 1 to polyethylene glycol (PEG)-mediated drought stress. Drought significantly decreased shoot length, shoot biomass and relative water content. Root length, malondialdehyde content, electrolyte leakage, activities of superoxide dismutase, peroxidase, catalase and amylase, and contents of soluble sugar, soluble protein and proline were increased by PEG-mediated drought. Untargeted metabolomics analysis identified 32 core… More >

Haojie Jia^1,2, Hong Du^1,2,*, Muhmmad Aslam^1,2, Tangcheng Li^1,2, Canqi Zheng^1,2, Xihui Xie^1,2, Nan Huang^1,2, Honghao Liang^1,2, Pengbing Pei^1,2, Ping Li^1,2, Weizhou Chen^1,2, Xiaojuan Liu^1,2

Phyton-International Journal of Experimental Botany, Vol.92, No.1, pp. 91-110, 2023, DOI:10.32604/phyton.2022.022663

Abstract Sulfur is an essential macronutrient for the growth of all photosynthetic organisms and plays important roles in different metabolic pathways. However, sulfur metabolism and its related research on macroalgae with important ecological value is rather limited. In this study, marine ecological valued macroalga Gracilariopsis lemaneiformis was used to study the general physiological responses and transcriptome profiling under the sulfate deficiency. The relative growth rate of algae under sulfate deficiency was statistically significantly lower than that of control after 6 days. However, no significant differences were observed in the pigments content and Fv/Fm value, indicating that the photosynthesis was not obviously… More >

Uttam Kumer Sarker¹, A. N. Md. Anamul Karim¹, F. M. Jamil Uddin¹, Ahmed Khairul Hasan¹, Najrul Islam¹, Md. Romij Uddin^1,*, Md. Alamgir Hossain², Sabry Hassan³, Mohamed M. Hassan³, Mahmoud F. K. Soliman⁴

Phyton-International Journal of Experimental Botany, Vol.91, No.12, pp. 2775-2789, 2022, DOI:10.32604/phyton.2022.023112

Abstract Chickpea yield is decreasing day by day due to drought stress, which could be an immense risk for future food security in developing countries. Management practices could be the most excellent approach to diminish loss due to this abiotic factor. The current research work was designed to explore the tolerance reaction of chickpea genotypes against management practices, through morphological and biochemical parameters and evaluate yield performance across drought prone location of Bangladesh. Four genotypes BD-6048, BD-6045, BD-6090, BD-6092 and eight management practices, e.g., severe water stress (SWS), i.e., without irrigation, 10 cm thick mulching with rice straw (MRS), 10 cm thick… More >

E. Afreen Banu^1,*, V. Rajamani²

Computer Systems Science and Engineering, Vol.44, No.3, pp. 2469-2487, 2023, DOI:10.32604/csse.2023.021332

Abstract In this work, we design a multisensory IoT-based online vitals monitor (hereinafter referred to as the VITALS) to sense four bedside physiological parameters including pulse (heart) rate, body temperature, blood pressure, and peripheral oxygen saturation. Then, the proposed system constantly transfers these signals to the analytics system which aids in enhancing diagnostics at an earlier stage as well as monitoring after recovery. The core hardware of the VITALS includes commercial off-the-shelf sensing devices/medical equipment, a powerful microcontroller, a reliable wireless communication module, and a big data analytics system. It extracts human vital signs in a pre-programmed interval of 30 min… More >

LEI WANG^1,#, QIUXIA DU^1,#, YISU SHI^1,#, MICHAEL ACKAH¹, PENG GUO¹, DANYAN ZHENG¹, MENGMENG WU¹, XIN JIN¹, PEILAN LI³, QIAONAN ZHANG¹, RUIXUE LI⁴, ZHI YIN³, MENGDI ZHAO^2,*, WEIGUO ZHAO^1,*

BIOCELL, Vol.46, No.10, pp. 2327-2342, 2022, DOI:10.32604/biocell.2022.021542

Abstract HMA2 (heavy metal ATPase 2) plays a crucial role in extracellular and intracellular Zn²⁺ transport across biomembranes, maintaining ion homeostasis, and playing an important role in the normal physiological metabolism, growth, and development of plants. In our study, a novel HMA2 gene, named MaHMA2, was isolated and cloned from white mulberry (Morus alba L.). The gene sequence obtained was 1,342 bp long, with an open reading frame of 1,194 bp, encoding a protein of 397 amino acids, with a predicted molecular mass of 42.852 kD and an isoelectric point of 7.53. This protein belonged to the PIB-type ATPase transport protein… More >

DOMENICO MARIA CARRETTA^1,§, MARINA DI DOMENICO^2,§, ROBERTO LOVERO³, ROBERTO ARRIGONI⁴, ANGELIKA ELZBIETA WEGIERSKA⁵, MARIAROSARIA BOCCELLINO^2,*, ANDREA BALLINI^2,6,*, IOANNIS ALEXANDROS CHARITOS^7,#, LUIGI SANTACROCE^5,#

BIOCELL, Vol.46, No.8, pp. 1779-1788, 2022, DOI:10.32604/biocell.2022.020009

Abstract The existence of an inflammatory process in the heart muscle, related to a progressive worsening of myocardial function, different etiopathogenetic mechanisms concur and often overlap, thus making the diagnosis and the therapeutic approach complex. As the COVID-19 pandemic progresses, the effects of the disease on the organ systems and in particular on the cardiovascular system are becoming more and more profound. Cardiac involvement is a well-known event with a high percentage of findings in the heart’s magnetic field, even in asymptomatic areas. There are numerous uncertainties regarding their evolution, in the long and short term, due not only to a… More >

YUNHUI ZHOU, YAJIE LIU, YUDAN WANG, CHUNXUE YANG^*

BIOCELL, Vol.46, No.8, pp. 1967-1978, 2022, DOI:10.32604/biocell.2022.019304

Abstract To investigate the effects of arbuscular mycorrhizal (AM) fungi on the growth and saline–alkaline tolerance of Potentilla anserina L., the seedlings were inoculated with Claroideoglomus etunicatum (W.N. Becker & Gerd.) C. Walker & A. Schüßler in pot cultivation. After 90 days of culture, saline–alkaline stress was induced with NaCl and NaHCO₃ solution according to the main salt components in saline–alkaline soils. Based on the physiological response of P. anserina to the stress in the preliminary experiment, the solution concentrations of 0 mmol/L, 75 mmol/L, 150 mmol/L, 225 mmol/L and 300 mmol/L were treated with stress for 10 days, respectively. The… More >