Ruikang Ma^1,2, Ziying Huang¹, Zexiu Zhang³, Ruohui Lu⁴, Menghan Li¹, Zhiyi Luo³, Mengni Li⁵, Pengyue Zhang³, Xiaohong Lin³, Guozhuang Zhang^1,*, Linlin Dong^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.11, pp. 3721-3748, 2025, DOI:10.32604/phyton.2025.072062 - 01 December 2025

Abstract Dendrobium officinale (DO) is a well-recognized medicinal and edible plant with a long history of application in traditional medicinal practices across China and Southeast Asia. Recent studies have demonstrated that DO is abundant in diverse bioactive compounds, including polysaccharides (DOP), flavonoids, alkaloids, and bibenzyls thought to exert a range of pharmacological effects, such as anti-tumor and immunomodulatory effects. However, our comprehensive understanding of two key aspects—pharmacological functions and biosynthetic mechanisms—of DO’s major constituents remains limited, especially when considered within the clinical contexts of traditional use. To address this gap, this study reviews DO’s historical applications, clinical effects, and… More > Graphic Abstract

Mengting Huang, Meiting Lu, Li Yang, Jiwen Long, Li Zhou^*

Journal of Renewable Materials, Vol.13, No.10, pp. 2077-2090, 2025, DOI:10.32604/jrm.2025.02025-0122 - 22 October 2025

Abstract Peach gum polysaccharide (PGP), a readily available natural polysaccharide, boasts substantial potential across diverse applications, yet its practical utility is severely limited by its vulnerability to bacterial growth and limited antioxidant activity. Herein, we introduced a simple and effective method to enhance the antibacterial and antioxidant properties of PGP by conjugating it with salicylic acid (SA). Cytotoxicity evaluation results confirmed that the resulting PGP-SA retains the excellent biocompatibility of PGP. Notably, PGP-SA demonstrates outstanding antibacterial activity against both Gram-positive (S. aureus) and Gram-negative (E. coli) bacteria, outperforming non-modified PGP. Its antibacterial mechanism is hypothesized to stem from… More > Graphic Abstract

Livanshee Gupta¹, Nouha Haoudi^2,3,*, Lanjelina Oinam¹, Ananya Mahajan¹, Sonia Morya^1,*

Phyton-International Journal of Experimental Botany, Vol.94, No.9, pp. 2669-2700, 2025, DOI:10.32604/phyton.2025.065058 - 30 September 2025

Abstract The trends of consuming or using eco-friendly, biodegradable products due to the change in the lifestyle of the people have led to the exploration of new sources from plants or animals. Seed mucilage (SeM) is an underexplored component of plants that can be brought into play to deal with such problems. Mucilage, a viscous polysaccharide that can be obtained when seeds like chia, flax, garden cress, and tomato get hydrated and form a slimy, gel-like substance around the seed coat, can be utilized due to its unique characteristics. It has been used in developing many… More >

Zhiqiang Jiang¹, Zili Li¹, Bin Liang², Miao He¹, Weishou Hu³, Jun Tang³, Chao Song⁴, Nanxin Zheng^5,*

FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.6, pp. 1397-1416, 2025, DOI:10.32604/fdmp.2025.062737 - 30 June 2025

Abstract Microbial polysaccharides, due to their unique physicochemical properties, have been shown to effectively enhance the stability of foam fracturing fluids. However, the combined application of microbial polysaccharides and surfactants under high-temperature and high-salinity conditions remain poorly understood. In this study, we innovatively investigate this problem with a particular focus on foam stabilization mechanisms. By employing the Waring blender method, the optimal surfactant-microbial polysaccharide blends are identified, and the foam stability, rheological properties, and decay behavior in different systems under varying conditions are systematically analyzed for the first time. The results reveal that microbial polysaccharides significantly More >

Kuo-Yang Huang¹, Sheng-Chien Lin^2,3, Chun-Hung Su^4,5,6, Sheng-Wen Wu^4,7, Ching-Chi Tseng^8,9, Wei-Chin Hung¹⁰, Shih-Pin Chen^4,5, Yu-Hsiang Kuan^2,3,*

BIOCELL, Vol.49, No.2, pp. 315-334, 2025, DOI:10.32604/biocell.2025.061073 - 28 February 2025

Abstract ABSTRACT: Background: Acute respiratory distress syndrome (ARDS) is the major therapeutic dilemma associated with significant inflammation and severe pulmonary dysfunction. Liriodendrin is a bioactive compound extract from traditional Chinese medicine, historically utilized for modulating inflammatory responses and alleviating symptoms in multiple disease models. Methods: At present, BALB/c mice were used to explore the effects of liriodendrin on lipopolysaccharide (LPS)-induced ARDS. Before LPS was administered, the mice were treated with either liriodendrin or dexamethasone. Leukocyte infiltration, lung edema, and alveolar-capillary barrier integrity were evaluated in the bronchoalveolar lavage fluid (BALF) and pulmonary parenchyma. The expression of adhesion… More >

LI SUN^1,#, SHICHAO ZHUO^2,#, XIAOXIN LI², HUSHENG KONG³, WEIWEI DU³, CHONG ZHOU⁴, JUNXING HUANG^1,*

Oncology Research, Vol.33, No.3, pp. 641-651, 2025, DOI:10.32604/or.2024.050057 - 28 February 2025

Abstract Background: Cisplatin (DDP) has been used in the treatment of various human cancers. However, DDP alone lacks efficacy in treating triple-negative breast cancer (TNBC), and its clinical application is often hampered by side effects. Astragalus polysaccharide (APS) is one of the active components extracted from Astragalus membranaceus and has gained attention for its various biological properties. This research is aimed to evaluate the effectiveness of a combination of APS and DDP on TNBC and explore the potential mechanisms. Methods: The efficacy and mechanisms of single or combined treatment were evaluated using Cell Counting Kit-8 (CCK8) assay, Annexin… More >

Desy Nurliasari¹, Awaly Ilham Dewantoro¹, Muhammad Adly Rahandi Lubis^2,3, Roni Kastaman^1,4,*, Mohamad Djali^3,5, Efri Mardawati^1,3, Devi Maulida Rahmah^1,3, Siti Nurhasanah^3,5, Akbar Hanif Dawam Abdullah^2,3, Lukmanul Hakim Zaini^6,7,*

Journal of Renewable Materials, Vol.13, No.1, pp. 181-197, 2025, DOI:10.32604/jrm.2024.056475 - 20 January 2025

Abstract Konjac is an ideal candidate for edible coatings on fruits due to its hydrophilic properties, film-forming ability, barrier properties, safety, and biodegradability. Meanwhile, the high market demand for strawberries necessitates post-harvest treatment to extend their shelf life and preserve their quality, as strawberries are known for their fragile skin and soft texture. To fully utilize konjac and develop high-quality coating films, native konjac flour (NKF) and konjac glucomannan (KGM) were extracted from its corm and used as a coating film for strawberries in the present study. Therefore, this study aimed to compare the physical properties… More > Graphic Abstract

ELMIRA YAKUPOVA¹, VALENTINA BABENKO^1,2, ALEXEY BOCHARNIKOV¹, KSENIYA FEDULOVA¹, DENIS SILACHEV^1,2, EGOR PLOTNIKOV^1,2,*

BIOCELL, Vol.48, No.12, pp. 1827-1834, 2024, DOI:10.32604/biocell.2024.058496 - 30 December 2024

Abstract Background: The active use of stem and progenitor cells in the therapy of various diseases requires the development of approaches for targeted modification of their properties. One such approach is the induction of a pro- or anti-inflammatory phenotype. Methods: In this study, we investigated the effect of a pro-inflammatory environment in vitro on multipotent mesenchymal stromal cells (MSC) by incubation with lipopolysaccharide (LPS). iCELLigence real-time cell analysis system was used for monitoring cell culture growth. Cell energy metabolism was assessed using the Seahorse XFp Analyzer. For the rat stroke experiment, we used a photoinduced thrombosis (PT)… More >

Flavia Oliveira Monteiro da Silva Abreu^1,2,*, Taysse Holanda¹, Joice Farias do Nascimento¹, Henety Nascimento Pinheiro¹, Rachel Menezes Castelo¹, Hélcio Silva dos Santos³, Thais Benincá⁴, Patrícia da Silva Malheiros⁴, Júlio César Sousa Prado⁵, Raquel de Oliveira Fontenelle⁵, Maria Madalena de Camargo Forte²

Journal of Renewable Materials, Vol.12, No.2, pp. 285-304, 2024, DOI:10.32604/jrm.2023.043919 - 11 March 2024

Abstract With the increase in antimicrobial resistance, it has become necessary to explore alternative approaches for combating and preventing diseases. DB-cinnamaldehyde (CNM) and Benzyl4-amino (B4AM) are bioactive compounds derived from chalcones but with restricted solubility in aqueous media. Nanoemulsions can enhance the solubility of compounds and can be a promising alternative in the development of novel antimicrobials, with reduced side effects and prolonged release. The objective of this study was to evaluate the stability of oil-in-water nanoemulsions loaded with two distinct types of chalcones at two different dosages, to propose a stable formulation with antimicrobial properties.… More > Graphic Abstract

Yong Qin^1,2, Xiaoyu Li^1,2, Yanhong Wu^1,2, Hai Wang³, Guiqi Han^1,2,3, Zhuyun Yan^1,2,*

Phyton-International Journal of Experimental Botany, Vol.93, No.1, pp. 119-135, 2024, DOI:10.32604/phyton.2023.046075 - 26 January 2024

Abstract Root exudates serve as crucial mediators for information exchange between plants and soil, and are an important evolutionary mechanism for plants’ adaptation to environmental changes. In this study, 15 different abiotic stress models were established using various stress factors, including drought (D), high temperature (T), nitrogen deficiency (N), phosphorus deficiency (P), and their combinations. We investigated their effects on the seedling growth of Salvia miltiorrhiza Bunge and the activities of Solid-Urease (S-UE), Solid-Nitrite Reductase (S-NiR), Solid-Nitrate Reductase (S-NR), Solid-Phosphotransferase (S-PT), and Solid-Catalase (S-CAT), as well as the contents of polysaccharides in the culture medium. The results… More >