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  • Open Access

    ARTICLE

    Performance Analysis of Foamed Fracturing Fluids Based on Microbial Polysaccharides and Surfactants in High-Temperature and High-Salinity Reservoirs

    Zhiqiang Jiang1, Zili Li1, Bin Liang2, Miao He1, Weishou Hu3, Jun Tang3, Chao Song4, Nanxin Zheng5,*

    FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.6, pp. 1397-1416, 2025, DOI:10.32604/fdmp.2025.062737 - 30 June 2025

    Abstract Microbial polysaccharides, due to their unique physicochemical properties, have been shown to effectively enhance the stability of foam fracturing fluids. However, the combined application of microbial polysaccharides and surfactants under high-temperature and high-salinity conditions remain poorly understood. In this study, we innovatively investigate this problem with a particular focus on foam stabilization mechanisms. By employing the Waring blender method, the optimal surfactant-microbial polysaccharide blends are identified, and the foam stability, rheological properties, and decay behavior in different systems under varying conditions are systematically analyzed for the first time. The results reveal that microbial polysaccharides significantly More >

  • Open Access

    ARTICLE

    Influence of Liriodendrin on NLRP3-Mediated Pyroptosis and Proinflammatory Pathways in Mice Experiencing Acute Respiratory Distress Syndrome Induced by Lipopolysaccharide

    Kuo-Yang Huang1, Sheng-Chien Lin2,3, Chun-Hung Su4,5,6, Sheng-Wen Wu4,7, Ching-Chi Tseng8,9, Wei-Chin Hung10, Shih-Pin Chen4,5, Yu-Hsiang Kuan2,3,*

    BIOCELL, Vol.49, No.2, pp. 315-334, 2025, DOI:10.32604/biocell.2025.061073 - 28 February 2025

    Abstract ABSTRACT: Background: Acute respiratory distress syndrome (ARDS) is the major therapeutic dilemma associated with significant inflammation and severe pulmonary dysfunction. Liriodendrin is a bioactive compound extract from traditional Chinese medicine, historically utilized for modulating inflammatory responses and alleviating symptoms in multiple disease models. Methods: At present, BALB/c mice were used to explore the effects of liriodendrin on lipopolysaccharide (LPS)-induced ARDS. Before LPS was administered, the mice were treated with either liriodendrin or dexamethasone. Leukocyte infiltration, lung edema, and alveolar-capillary barrier integrity were evaluated in the bronchoalveolar lavage fluid (BALF) and pulmonary parenchyma. The expression of adhesion… More >

  • Open Access

    ARTICLE

    Astragalus polysaccharide enhances the therapeutic efficacy of cisplatin in triple-negative breast cancer through multiple mechanisms

    LI SUN1,#, SHICHAO ZHUO2,#, XIAOXIN LI2, HUSHENG KONG3, WEIWEI DU3, CHONG ZHOU4, JUNXING HUANG1,*

    Oncology Research, Vol.33, No.3, pp. 641-651, 2025, DOI:10.32604/or.2024.050057 - 28 February 2025

    Abstract Background: Cisplatin (DDP) has been used in the treatment of various human cancers. However, DDP alone lacks efficacy in treating triple-negative breast cancer (TNBC), and its clinical application is often hampered by side effects. Astragalus polysaccharide (APS) is one of the active components extracted from Astragalus membranaceus and has gained attention for its various biological properties. This research is aimed to evaluate the effectiveness of a combination of APS and DDP on TNBC and explore the potential mechanisms. Methods: The efficacy and mechanisms of single or combined treatment were evaluated using Cell Counting Kit-8 (CCK8) assay, Annexin… More >

  • Open Access

    ARTICLE

    An Evaluation on Physical Characteristics of Konjac Polysaccharides-Based Film Coating and Its Application for Strawberries Preservation

    Desy Nurliasari1, Awaly Ilham Dewantoro1, Muhammad Adly Rahandi Lubis2,3, Roni Kastaman1,4,*, Mohamad Djali3,5, Efri Mardawati1,3, Devi Maulida Rahmah1,3, Siti Nurhasanah3,5, Akbar Hanif Dawam Abdullah2,3, Lukmanul Hakim Zaini6,7,*

    Journal of Renewable Materials, Vol.13, No.1, pp. 181-197, 2025, DOI:10.32604/jrm.2024.056475 - 20 January 2025

    Abstract Konjac is an ideal candidate for edible coatings on fruits due to its hydrophilic properties, film-forming ability, barrier properties, safety, and biodegradability. Meanwhile, the high market demand for strawberries necessitates post-harvest treatment to extend their shelf life and preserve their quality, as strawberries are known for their fragile skin and soft texture. To fully utilize konjac and develop high-quality coating films, native konjac flour (NKF) and konjac glucomannan (KGM) were extracted from its corm and used as a coating film for strawberries in the present study. Therefore, this study aimed to compare the physical properties… More > Graphic Abstract

    An Evaluation on Physical Characteristics of Konjac Polysaccharides-Based Film Coating and Its Application for Strawberries Preservation

  • Open Access

    ARTICLE

    Changes in bioenergetics and neuroprotective properties of mesenchymal stromal cells after LPS treatment

    ELMIRA YAKUPOVA1, VALENTINA BABENKO1,2, ALEXEY BOCHARNIKOV1, KSENIYA FEDULOVA1, DENIS SILACHEV1,2, EGOR PLOTNIKOV1,2,*

    BIOCELL, Vol.48, No.12, pp. 1827-1834, 2024, DOI:10.32604/biocell.2024.058496 - 30 December 2024

    Abstract Background: The active use of stem and progenitor cells in the therapy of various diseases requires the development of approaches for targeted modification of their properties. One such approach is the induction of a pro- or anti-inflammatory phenotype. Methods: In this study, we investigated the effect of a pro-inflammatory environment in vitro on multipotent mesenchymal stromal cells (MSC) by incubation with lipopolysaccharide (LPS). iCELLigence real-time cell analysis system was used for monitoring cell culture growth. Cell energy metabolism was assessed using the Seahorse XFp Analyzer. For the rat stroke experiment, we used a photoinduced thrombosis (PT)… More >

  • Open Access

    ARTICLE

    Evaluation of the Antibacterial and Antifungal Capacity of Nanoemulsions Loaded with Synthetic Chalcone Derivatives Di-Benzyl Cinnamaldehyde and Benzyl 4-Aminochalcone

    Flavia Oliveira Monteiro da Silva Abreu1,2,*, Taysse Holanda1, Joice Farias do Nascimento1, Henety Nascimento Pinheiro1, Rachel Menezes Castelo1, Hélcio Silva dos Santos3, Thais Benincá4, Patrícia da Silva Malheiros4, Júlio César Sousa Prado5, Raquel de Oliveira Fontenelle5, Maria Madalena de Camargo Forte2

    Journal of Renewable Materials, Vol.12, No.2, pp. 285-304, 2024, DOI:10.32604/jrm.2023.043919 - 11 March 2024

    Abstract With the increase in antimicrobial resistance, it has become necessary to explore alternative approaches for combating and preventing diseases. DB-cinnamaldehyde (CNM) and Benzyl4-amino (B4AM) are bioactive compounds derived from chalcones but with restricted solubility in aqueous media. Nanoemulsions can enhance the solubility of compounds and can be a promising alternative in the development of novel antimicrobials, with reduced side effects and prolonged release. The objective of this study was to evaluate the stability of oil-in-water nanoemulsions loaded with two distinct types of chalcones at two different dosages, to propose a stable formulation with antimicrobial properties.… More > Graphic Abstract

    Evaluation of the Antibacterial and Antifungal Capacity of Nanoemulsions Loaded with Synthetic Chalcone Derivatives Di-Benzyl Cinnamaldehyde and Benzyl 4-Aminochalcone

  • Open Access

    ARTICLE

    The Effect of Soil Enzymes and Polysaccharides Secreted by the Roots of Salvia miltiorrhiza Bunge under Drought, High Temperature, and Nitrogen and Phosphorus Deficits

    Yong Qin1,2, Xiaoyu Li1,2, Yanhong Wu1,2, Hai Wang3, Guiqi Han1,2,3, Zhuyun Yan1,2,*

    Phyton-International Journal of Experimental Botany, Vol.93, No.1, pp. 119-135, 2024, DOI:10.32604/phyton.2023.046075 - 26 January 2024

    Abstract Root exudates serve as crucial mediators for information exchange between plants and soil, and are an important evolutionary mechanism for plants’ adaptation to environmental changes. In this study, 15 different abiotic stress models were established using various stress factors, including drought (D), high temperature (T), nitrogen deficiency (N), phosphorus deficiency (P), and their combinations. We investigated their effects on the seedling growth of Salvia miltiorrhiza Bunge and the activities of Solid-Urease (S-UE), Solid-Nitrite Reductase (S-NiR), Solid-Nitrate Reductase (S-NR), Solid-Phosphotransferase (S-PT), and Solid-Catalase (S-CAT), as well as the contents of polysaccharides in the culture medium. The results… More >

  • Open Access

    REVIEW

    Research Progress on Structure and Bioactivity of Longan Polysaccharide

    Xiaolong Ji1,#, Shuli Zhang1,#, Xueyuan Jin2, Xin Yuan1, Siqi Zhang1, Xudan Guo3,*, Fengcheng Shi4,*, Yanqi Liu1

    Journal of Renewable Materials, Vol.11, No.4, pp. 1631-1642, 2023, DOI:10.32604/jrm.2023.025844 - 01 December 2022

    Abstract Longan originates from southern China and has high nutritional and health value. Recent phytochemistry and pharmacology studies have shown that polysaccharides are a main bioactive component of longan. Longan polysaccharides possess antioxidant, anti-aging, anti-tumor, immunomodulatory, and other bioactivities. Hot-water extraction, ethanol precipitation, and ultrasonic extraction are generally used to extract water-soluble longan polysaccharides. However, the relationship between the structure and bioactivity of longan polysaccharides remains unclear, requiring further investigation. The aim of this review is to evaluate the current literature focusing on the extraction, purification, structural characterization, and biological activity of longan polysaccharides. We believe More >

  • Open Access

    ARTICLE

    Azospirillum brasilense and Saccharomyces cerevisiae as Alternative for Decrease the Effect of Salinity Stress in Tomato (Lycopersicon esculentum) Growth

    Ali Abdelmoteleb1, Daniel Gonzalez-Mendoza2,*, Ahmed Mohamed Elbaalawy3

    Phyton-International Journal of Experimental Botany, Vol.91, No.1, pp. 21-32, 2022, DOI:10.32604/phyton.2022.016227 - 16 August 2021

    Abstract The salinity stress is one of the most relevant abiotic stresses that affects the agricultural production. The present study was performed to study the improvement of the salt tolerance of tomato plants which is known for their susceptibility to salt stress. The present study aimed to assess to what extent strain Azospirillum brasilense (N040) and Saccharomyces cerevisiae improve the salt tolerance to tomato plants treated with different salt concentration. The inoculant strain A. brasilense (N040) was previously adapted to survive up to 7% NaCl in the basal media. A greenhouse experiment was conducted to evaluate the effect of… More >

  • Open Access

    ARTICLE

    Angelica sinensis polysaccharides ameliorate 5-flourouracil-induced bone marrow stromal cell proliferation inhibition via regulating Wnt/β-catenin signaling

    HANXIANZHI XIAO, RONGJIA QI, ZILING WANG, MINGHE XIAO, YUE XIANG, YAPING WANG, LU WANG*

    BIOCELL, Vol.45, No.4, pp. 1045-1058, 2021, DOI:10.32604/biocell.2021.015039 - 22 April 2021

    Abstract Chemotherapy may cause cellular oxidative stress to bone marrow. Oxidative damage of bone marrow hematopoietic microenvironment is closely related to chronic myelosuppression after chemotherapeutic treatment. Angelica sinensis polysaccharides (ASP) are major effective ingredients of traditional Chinese medicine Angelica with multi-target anti-oxidative stress features. In the current study, we investigated the protective roles and mechanisms of ASP on chemotherapy-induced bone marrow stromal cell (BMSC) damage. The human bone marrow stromal cell line HS-5 cells were divided into control group, 5-FU group, 5-FU + ASP group, and 5-FU + LiCl group to investigate the mechanism of ASP to… More >

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