Salim Lachkar^*, Ahmed Ibrahimi, Imad Boualaoui, Hachem El Sayegh, Yassine Nouini

Canadian Journal of Urology, Vol.32, No.3, pp. 145-165, 2025, DOI:10.32604/cju.2025.064912 - 27 June 2025

Abstract Introduction: When conservative treatments fail, botulinum toxin A (BoNT-A) is an option for refractory idiopathic overactive bladder (OAB). This review evaluates the efficacy, safety, and predictive factors for BoNT-A in this situation. Material and Methods: A literature search up to January 2025 was performed using PubMed, Google Scholar, and Embase to assess efficacy, safety, and predictors of adverse events (AE) related to BoNT-A. The risk of bias was assessed using the Risk of Bias 2 (RoB 2) tool for randomized studies and the Critical Appraisal Skills Programme (CASP) checklist for cohort studies. The quality of the… More >

Shoumiao Li^*†, Baozhong Li^†, Jiaxiang Wang^*, Da Zhang^*, Zhiqiang Liu^†, Zhizhong Zhang^†, Wei Zhang^†, Yunjie Wang^†, Dongxiao Bai^†, Jianyun Guan^†, Yong Zhang^†

Oncology Research, Vol.25, No.1, pp. 93-97, 2017, DOI:10.3727/096504016X14719078133564

Abstract The identification of reliable predictors of chemotherapy sensitivity and early screening of adenocarcinoma of gastroesophageal junction (AGEJ) patients who are resistant to chemotherapy has become an important area of clinical and translational research. We aimed to investigate the predictive value of seven cancerassociated cellular proteins for neoadjuvant chemotherapy in AGEJ patients. Clinical data of 93 patients who received neoadjuvant chemotherapy for locally advanced AGEJ between June 2010 and December 2014 were reviewed. All patients were administered the combination regimen of S-1 and oxaliplatin (SOX). Expression of P-glycoprotein (P-gp), glutathione S-transferase-p (GST-π), topoisomerase II (topo II),… More >

Marie N’gamba^1,*, Souhil Lebdai^1,*, Camille Hasting², Paul Panayotopoulos¹, Myriam Ammi¹, Loïc Sentilhes², Philippe Descamps², Abdel-Rahmène Azzouzi¹, Pierre Bigot¹

Canadian Journal of Urology, Vol.22, No.2, pp. 7732-7738, 2015

Abstract Introduction: The aim of this study was to identify predictive factors of urolithiasis etiology for acute renal colic (ARC) during pregnancy.
Materials and methods: We performed a retrospective review of all pregnant women hospitalized for an ARC between January 2007 and October 2012 in the department of Obstetrics and Gynecology of a University Hospital. Univariate and multivariate regression models were used to assess potential predictive factors of urolithiasis etiology.
Results: We included 82 patients. A urolithiasis was identified in 24 (29.3%) patients. In univariate analysis, we identified the following predictive factors for a urolithiasis etiology: primiparity… More >

Fiona Mei Wen Wu¹, Melissa Hui Wen Tay¹, Zhaojin Chen², Bee Choo Tai^3,4, Lincoln Guan Lim Tan¹, Lata Raman¹, Ho Yee Tiong¹

Canadian Journal of Urology, Vol.21, No.4, pp. 7351-7357, 2014

Abstract Introduction: To compare baseline renal function and identify predictive factors in patients undergoing radical nephrectomy (RN) or donor nephrectomy (DN) and their risk of subsequent chronic kidney disease (CKD) after surgery.
Materials and methods: A retrospective review of patients with no baseline CKD undergoing RN (n = 88) and DN (n = 58) from 2000 to 2008 was performed. Baseline and postoperative renal function (eGFR) was determined using the Modification of Diet in Renal Disease (MDRD) formula. CKD was defined as eGFR < 60 mL/min/1.73 m² according to the National Kidney Foundation guidelines.
Results: Before surgery, patients undergoing… More >

Bob Djavan

Canadian Journal of Urology, Vol.18, No.1, pp. 5536-5536, 2011

Abstract This article has no abstract. More >

Jacobo Arce, Josep M. Gaya, Jorge Huguet, Oscar Rodriguez, Joan Palou, Humberto Villavicencio

Canadian Journal of Urology, Vol.18, No.1, pp. 5529-5536, 2011

Abstract Objectives: To determine which patients may benefit from prostate-sparing surgery and which factors are predictive of invasive prostatic involvement.
Materials and methods: A total of 717 men underwent radical cystoprostatectomy (RC) for bladder transitional cell carcinoma (TCC) between 1978 and 2002. Analysis of prostatic urethral involvement by transitional cell carcinoma (pTCC) and of invasive prostatic involvement by TCC was performed according to recurrence, presence of carcinoma in situ (CIS) and multifocality, previous intravesical chemotherapy, grade, stage and location of bladder tumor, presence of CIS in precystectomy transurethral resection (TUR) and indication for RC.
Results: pTCC was present in… More >

Nicolas B. Delongchamps¹, Marc Zerbib¹, Arnaud Méjean², Yannick Rouach², Bernard Debré¹, Michaël Peyromaure^1,2

Canadian Journal of Urology, Vol.16, No.5, pp. 4813-4819, 2009

Abstract Introduction: Many studies have analyzed outcomes following salvage radiation therapy (RT) after biochemical recurrence--defined as the presence of detectable serum prostate-specific antigen (PSA)--following radical prostatectomy (RP). However, the management of patients with detectable PSA following RP, which is not specific for tumor recurrence, is a matter of debate. This study aimed to evaluate oncological results of three-dimensional conformal RT (3D-CRT) in patients who had biochemical recurrence.
Materials and methods: The study included patients who underwent RP, who had a postoperative PSA level--determined between 2 and 4 months after surgery--that was greater than 0.1 ng/ml, and who subsequently… More >

Alvaro Morales

Canadian Journal of Urology, Vol.15, No.5, pp. 4256-4256, 2008

Abstract This article has no abstract. More >

Christopher J. DiBlasio¹, Jessica Hammett¹, John B. Malcolm¹, Beth A. Judge², Jamie H. Womack², Matthew C. Kincade¹, Mitchell L. Ogles¹, John M. Mancini¹, Anthony L. Patterson¹, Robert W. Wake¹, Ithaar H. Derweesh¹

Canadian Journal of Urology, Vol.15, No.5, pp. 4249-4256, 2008

Abstract Objective: Androgen deprivation therapy (ADT) remains a widely utilized modality for treatment of localized and advanced prostate cancer. While ADT-induced alterations in testosterone have demonstrated impacts on quality of life, the effects on mental health remain ill-defined. We investigated the prevalence of de novo psychiatric illness and predictive factors following ADT induction for prostate cancer.
Materials and methods: We retrospectively reviewed patients receiving ADT for prostate cancer at our institution between 1/1989-7/2005, excluding men receiving only neoadjuvant ADT. Variables included age, race, body mass index, prostate-specific antigen (PSA), Gleason sum, clinical stage, ADT type (medical/surgical) and schedule… More >

William A. Gourlay¹, Lynn Stothers², Li Liu^1,3

Canadian Journal of Urology, Vol.12, No.1, pp. 2511-2520, 2005

Abstract Introduction: Live donor kidney transplantation (LDKT) is both medically and economically superior to cadaver kidney transplantation in the treatment of patients with chronic renal failure. Unfortunately, fewer than 50% of patients on the transplant waiting list have a relative or friend who contacts the transplant program about possible donation. We hypothesized that both the potential recipient and potential donor have identifiable and modifiable characteristics that contribute to the likelihood of a live donor transplant.
Materials and methods: Specifically-designed and validated questionnaires addressing personal characteristics, knowledge and beliefs about LDKT were mailed to patients who had previously received… More >