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  • Open Access

    ARTICLE

    An Electricity-Carbon Synergy-Driven Optimization Method for Low-Carbon Operation of Multi-Energy Parks

    Jiangyang Yuan1, Jiaowen Wu1, Yi Gao1, Yuhao Fu2, Yuntao Bu2, Tianyu Chen2, Hao Yu2,*

    Energy Engineering, Vol.123, No.2, 2026, DOI:10.32604/ee.2025.070715 - 27 January 2026

    Abstract In the pursuit of carbon peaking and neutrality goals, multi-energy parks, as major energy consumers and carbon emitters, urgently require low-carbon operational strategies. This paper proposes an electricity-carbon synergy-driven optimization method for the low-carbon operation of multi-energy parks. The method integrates multi-energy complementary scheduling with a tiered carbon trading mechanism to balance operational security, economic efficiency, and environmental objectives. A mixed-integer linear programming model is developed to characterize the coupling relationships and dynamic behaviors of key equipment, including photovoltaic systems, ground-source heat pumps, thermal storage electric boilers, combined heat and power units, and electrical energy… More >

  • Open Access

    ARTICLE

    Analysis and Defense of Attack Risks under High Penetration of Distributed Energy

    Boda Zhang1,*, Fuhua Luo1, Yunhao Yu1, Chameiling Di1, Ruibin Wen1, Fei Chen2

    Energy Engineering, Vol.123, No.2, 2026, DOI:10.32604/ee.2025.069323 - 27 January 2026

    Abstract The increasing intelligence of power systems is transforming distribution networks into Cyber-Physical Distribution Systems (CPDS). While enabling advanced functionalities, the tight interdependence between cyber and physical layers introduces significant security challenges and amplifies operational risks. To address these critical issues, this paper proposes a comprehensive risk assessment framework that explicitly incorporates the physical dependence of information systems. A Bayesian attack graph is employed to quantitatively evaluate the likelihood of successful cyber attacks. By analyzing the critical scenario of fault current path misjudgment, we define novel system-level and node-level risk coupling indices to precisely measure the… More >

  • Open Access

    ARTICLE

    Ab initio Investigation of Structural Units and Raman Vibrational Characteristics in Ge-Se-Te Glasses

    Xuecai Han, Yilin Tong, Jiaqi Bao, Kan Yu*

    Chalcogenide Letters, Vol.23, No.1, 2026, DOI:10.32604/cl.2026.075604 - 26 January 2026

    Abstract Chalcogenide glasses in the Ge-Se-Te system possess wide infrared transparency and strong optical nonlinearity, yet the microscopic origin of their vibrational behavior remains unclear. Using ab initio calculations, we analyzed Raman-active modes in GeSexTe4−x (x = 0–4) tetrahedra, edge-sharing tetrahedra, and ethane-like Ge2Se2xTe6−2x (x = 0–3) clusters. For GeSexTe4−x (x = 0–4) tetrahedra, the symmetric stretching vibrations exhibit two families: Ge-Se-dominated and Ge-Te-dominated modes, both showing monotonic redshifts as the number of same-type bonds increases. In edge-sharing tetrahedra, the Ge-Ch-Ge-Ch (Ch = Se or Te) four-membered-ring breathing frequency decreases with higher Te content, and a comparable softening is More >

  • Open Access

    REVIEW

    Recent Advances in Hydrothermal Carbonization of Biomass: The Role of Process Parameters and the Applications of Hydrochar

    Cheng Zhang, Rui Zhang, Yu Shao, Jiabin Wang, Qianyue Yang, Fang Xie, Rongling Yang, Hongzhen Luo*

    Journal of Renewable Materials, Vol.14, No.1, 2026, DOI:10.32604/jrm.2025.02025-0157 - 23 January 2026

    Abstract Biomass is a resource whose organic carbon is formed from atmospheric carbon dioxide. It has numerous characteristics such as low carbon emissions, renewability, and environmental friendliness. The efficient utilization of biomass plays a significant role in promoting the development of clean energy, alleviating environmental pressures, and achieving carbon neutrality goals. Among the numerous processing technologies of biomass, hydrothermal carbonization (HTC) is a promising thermochemical process that can decompose and convert biomass into hydrochar under relatively mild conditions of approximately 180°C–300°C, thereby enabling its efficient resource utilization. In addition, HTC can directly process feedstocks with high… More >

  • Open Access

    REVIEW

    A Systematic Review of Frameworks for the Detection and Prevention of Card-Not-Present (CNP) Fraud

    Kwabena Owusu-Mensah*, Edward Danso Ansong , Kofi Sarpong Adu-Manu, Winfred Yaokumah

    Journal of Cyber Security, Vol.8, pp. 33-92, 2026, DOI:10.32604/jcs.2026.074265 - 20 January 2026

    Abstract The rapid growth of digital payment systems and remote financial services has led to a significant increase in Card-Not-Present (CNP) fraud, which is now the primary source of card-related losses worldwide. Traditional rule-based fraud detection methods are becoming insufficient due to several challenges, including data imbalance, concept drift, privacy concerns, and limited interpretability. In response to these issues, a systematic review of twenty-four CNP fraud detection frameworks developed between 2014 and 2025 was conducted. This review aimed to identify the technologies, strategies, and design considerations necessary for adaptive solutions that align with evolving regulatory standards.… More >

  • Open Access

    ARTICLE

    SDHA Deficiency in Hepatocellular Carcinoma Promotes Tumor Progression through Succinate-Induced M2 Macrophage Polarization

    Xinyang Li1,2,3,#, Luyuan Ma1,2,3,#, Chuan Shen1,2,3, Ruolan Gu1,2,3, Shilong Dong1,2,3, Mingjie Liu1,2,3, Ying Xiao1,2,3, Wenpeng Liu1,2,3, Yuexia Liu1,2,3, Caiyan Zhao1,2,3,*

    Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.073179 - 19 January 2026

    Abstract Background: Hepatocellular carcinoma (HCC) is an aggressive and lethal malignancy. Metabolic reprogramming dynamically remodels the tumor microenvironment (TME) and drives HCC progression. This study investigated the mechanism through which metabolic reprogramming remodels the TME in HCC. Methods: HCC patient transcriptome data were subjected to bioinformatics analysis to identify differentially expressed genes and immune infiltration status. Immunohistochemical analysis was performed to determine the correlation between succinate dehydrogenase complex subunit A (SDHA) expression and M2 macrophage infiltration. SDHA-knockdown or SDHA-overexpressing HCC cells were used for in vitro experiments, including co-culturing, flow cytometry, and enzyme-linked immunosorbent assay. Western blotting… More >

  • Open Access

    ARTICLE

    Gut Associated Metabolites Enhance PD-L1 Blockade Efficacy in Prostate Cancer

    Ke Liu1,2,3,#, Xia Xue1,2,3,#, Haiming Qin4,5,#, Jiaying Zhu6,#, Meng Jin1,6, Die Dai6, Youcai Tang1, Ihtisham Bukhari1, Hangfan Liu1, Chunjing Qiu1, Feifei Ren1, Pengyuan Zheng1,2,3, Yang Mi1,2,3,*, Weihua Chen6,7,*

    Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.072661 - 19 January 2026

    Abstract Background: The gut microbiome has emerged as a critical modulator of cancer immunotherapy response. However, the mechanisms by which gut-associated metabolites influence checkpoint blockade efficacy in prostate cancer (PC) remain not fully explored. The study aimed to explore how gut metabolites regulate death-ligand 1 (PD-L1) blockade via exosomes and boost immune checkpoint inhibitors (ICIs) in PC. Methods: We recruited 70 PC patients to set up into five subgroups. The integrated multi-omics analysis was performed. In parallel, we validated the function of gut microbiome-associated metabolites on PD-L1 production and immunotherapy treatment efficacy in PC cell lines… More >

  • Open Access

    ARTICLE

    Thimerosal Inhibits Tumor Malignant Progression through Direct Action and Enhancing the Efficacy of PD-1-Based Immunotherapy

    Ping Wang1,2,#, Yan-Han Chen1,2,#, Ze-Tao Zhan1,2, Jun-Xiang Zeng1,2, Yu Chen3,4, Yuan Lin1,2, Tao Chen1,5,*, Wei-Jie Zhou1,2,5,*

    Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.071902 - 19 January 2026

    Abstract Background: Thimerosal is a mercury-containing preservative widely used in vaccines. This study aimed to investigate its potential antitumor effects and mechanisms in solid malignancies, particularly colorectal cancer (CRC) and melanoma. Methods: A combination of in vitro and in vivo approaches was employed. Cell proliferation, apoptosis, migration, and invasion were assessed using Cell Counting Kit-8 (CCK-8), colony formation, ATP viability, Western blotting, flow cytometry, wound-healing and Transwell assays. Subcutaneous, lung metastases, and Azoxymethane/Dextran Sulfate Sodium Salt (AOM/DSS)-induced colitis-associated CRC models were established to examine antitumor efficacy and safety. The functional role of mercury ions was validated using structural… More >

  • Open Access

    ARTICLE

    PIK3R1 as a Gastric Cancer Biomarker Linked to CD73+ Treg-Mediated Immunosuppression

    Bu Zou1,#, Yi-En Xu2,#, Hui-Chan He3, Zu-Lu Ye2, Da-Lei Zhou2, Cai-Yun He2,*, Chan Huang4,*

    Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.069453 - 19 January 2026

    Abstract Objectives: Gastric cancer (GC) remains a major global health concern, and Phosphoinositide-3-Kinase Regulatory Subunit 1 (PIK3R1), a regulatory subunit of the PI3K signaling pathway, may play a critical yet underexplored role in GC progression. This study aimed to investigate the prognostic significance of PIK3R1 in GC and its association with the tumor immune microenvironment. Methods: PIK3R1 expression and its clinical relevance were analyzed using datasets from GC patients who underwent gastrectomy, including cohorts from The Cancer Genome Atlas (TCGA) and the Sun Yat-sen University Cancer Center (SYSUCC). Prognostic models integrating PIK3R1 expression with clinical parameters… More >

  • Open Access

    ARTICLE

    3D Photogrammetric Modelling for Digital Twin Development: Accuracy Assessment Using UAV Multi-Altitude Imaging

    Nur Afikah Juhari, Khairul Nizam Tahar*

    Revue Internationale de Géomatique, Vol.35, pp. 1-11, 2026, DOI:10.32604/rig.2026.070991 - 19 January 2026

    Abstract The use of Unmanned Aerial Vehicles (UAVs) in photogrammetry has grown rapidly due to enhanced flight stability, high-resolution imaging, and advanced Structure from Motion (SfM) algorithms. This study investigates the potential of UAVs as a cost-effective alternative to Terrestrial Laser Scanners (TLS) for 3D building reconstruction. A 3D model of Bangunan Sarjana was generated in Agisoft Metashape Professional v.2.0.2 using 492 aerial images captured at flying altitudes of 40, 50, and 60 m. Ground control points were established using GNSS (RTK-VRS), and Total Station measurements were employed for accuracy validation. The results indicate that the 60 More >

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