Qiuxiao Mou, Haoyu Gui, Xianghong Tang^*, Jianguang Lu

CMC-Computers, Materials & Continua, Vol.87, No.3, 2026, DOI:10.32604/cmc.2026.076251 - 09 April 2026

Abstract Electrocardiogram (ECG) is a widely used non-invasive tool for diagnosing cardiovascular diseases. ECG zero-shot classification involves pre-training a model on a large dataset to classify unknown disease categories. However, existing ECG feature extraction networks often neglect key lead signals and spatial topology dependencies during cross-modal alignment. To address these issues, we propose a multimodal channel compression graph attention alignment network (MCCGAA). MCCGAA incorporates a channel attention module (CAM) to effectively integrate key lead features and a graph attention-based alignment network to capture spatial dependencies, enhancing cross-modal alignment. Additionally, MCCGAA employs a log-sum-exp loss function, improving More >

Guoguan Wu^1,2, Baipei Liu^1,3, Dawei Jiang^1,2,*, Haorui Yu¹, Jiayu Fu^1,2, Chengze Yu¹, Hanbin Wang¹, Miaojun Xu^1,2,*, Zijian Wu⁴, Bin Li^1,2,*

Journal of Polymer Materials, Vol.43, No.1, 2026, DOI:10.32604/jpm.2026.075384 - 03 April 2026

Abstract Epoxy resins are extensively employed in the construction, electronics, automotive, and aerospace industries owing to their outstanding mechanical strength, chemical resistance, and electrical insulation. However, their intrinsic flammability, poor wear resistance, and hydrophilicity significantly restrict broader applications. To address these challenges, a novel multifunctional coating (CEOS-DOPO-PDMS) has been designed and fabricated via an NP-GLIDE approach. The system integrates 9,10-dihydro-9-oxa-10-phosphaphenanthrene-10-oxide (DOPO) as a reactive phosphorus-based flame retardant, epoxy-terminated polydimethylsiloxane (EP-PDMS) as a hydrophobic segment, and cycloaliphatic epoxy-functionalized oligosiloxanes (CEOS) as a cross-linking co-reactant. The resulting CEOS-DOPO-PDMS hybrid precursor was blended with bisphenol A diglycidyl ether (DGEBA)… More > Graphic Abstract

Naoual Houaidji¹, Kenza Kamli^2,*, Zakaria Hadef², Houssem Eddine Chouial³, Marwa Bendaia¹

Chalcogenide Letters, Vol.23, No.3, 2026, DOI:10.32604/cl.2026.076383 - 03 April 2026

Abstract We present a systematic investigation of FeS₂ thin films deposited by ultrasonic spray pyrolysis (USP) at different deposition times (15–40 min), with the aim of understanding their structural, optical, and electrical evolution and their suitability for heterojunction device applications. Particular attention is given to the integration of the optimized FeS₂ layer with a Co-doped SnS₂ bottom layer to form a p–n heterojunction. Structural analysis by X-ray diffraction reveals a transition from an amorphous/oxidized phase at short deposition times toward well-crystallized pyrite after 25 min, while the 40-min film exhibits the most intense reflections and the largest crystallite… More >

Egidijus Žukauskas^1,*, Damira Smagulova¹, Elena Jasiūnienė^1,2

CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.3, 2026, DOI:10.32604/cmes.2026.077492 - 30 March 2026

Abstract Adhesively bonded joints are widely used in modern lightweight structures due to their high strength-to-weight ratio and design flexibility. However, the reliable non-destructive evaluation of bond integrity remains a significant challenge. This study presents a numerical investigation of adhesively bonded joints with different adhesive properties using ultrasonic guided waves. The main focus of the investigation is to evaluate the feasibility of using guided waves to assess bond integrity, particularly for detecting challenging weak bonds. For this purpose, a theoretical analysis of dispersion curves was conducted, revealing that the S0 Lamb wave mode is significantly sensitive… More >

Saira Ali Bhatti¹, Maqbool Khan^2,*, Arshad Ahmad³, Muhammad Shahid Anwar⁴, Leila Jamel⁵, Aisha M. Mashraqi⁶, Wadee Alhalabi^7,*

CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.3, 2026, DOI:10.32604/cmes.2026.074688 - 30 March 2026

Abstract Medical imaging is essential in modern health care, allowing accurate diagnosis and effective treatment planning. These images, however, often demonstrate low contrast, noise, and brightness distortion that reduce their diagnostic reliability. This review presents a structured and comprehensive analysis of advanced histogram equalization (HE)-based techniques for medical image enhancement. Our review methodology encompasses: (1) classical HE approaches and related limitations in medical domains; (2) adaptive schemes like Adaptive Histogram Equalization (AHE) and Contrast Limited Adaptive Histogrma Equalization (CLAHE) and their advance variants; (3) brightness-preserving schemes like BBHE and MMBEBHE and related algorithms; (4) dynamic and More > Graphic Abstract

Huda F. Al-Shahad^1,2, Razali Yaakob^1,*, Nurfadhlina Mohd Sharef¹, Hazlina Hamdan¹, Hasyma Abu Hassan³, Xiaoyi Jiang⁴

CMES-Computer Modeling in Engineering & Sciences, Vol.146, No.3, 2026, DOI:10.32604/cmes.2025.074109 - 30 March 2026

Abstract Currently, thyroid diseases are prevalent worldwide; therefore, it is necessary to develop techniques that help doctors improve their diagnostic skills for such diseases. In previous studies, 2-dimensional convolutional neural network (2D CNN) techniques were employed to classify thyroid nodules as benign and malignant without detecting the presence of thyroid nodules in the obtained ultrasound images. To address this issue, we propose a 3-dimensional convolutional neural network (3D CNN) for thyroid nodule detection. The proposed CNN exploits the 3D information and spatial features contained in ultrasound images and generates distinctive features during its training using multiple… More >

Xu Wang^1,2, Cui-Hong Cao^2,3, Xiao-Ling Liao⁴, Xing-Yong Jiang⁵, Mark D. Griffiths⁶, I-Hua Chen^7,*, Chung-Ying Lin^8,9,*

International Journal of Mental Health Promotion, Vol.28, No.3, 2026, DOI:10.32604/ijmhp.2026.075149 - 31 March 2026

Abstract Background: The recently developed Depression, Anxiety, and Stress Scales–Youth Version (DASS-Y) shows promise as a tool for assessing youth mental health, but its consistency across timepoints and diverse ages remains underexplored. The present study evaluated whether the DASS-Y reliably measured depression, anxiety, and stress among school-aged youth (aged 9–18 years) across distinct time periods and educational stages. Methods: Two studies were conducted. Study 1 examined consistency over three months using data from 736 Central Chinese high school students who completed surveys at both timepoints. Study 2 tested consistency across educational levels among 2321 primary and 1676… More >

Kuan-Hao Lin¹, Yu-Ju Lin¹, Yu-Bin Hong¹, Meng-Huai Hsu¹, Zhen-Xiang Liao¹, Shuo-Yu Chang¹, Chiou-Hwa Yuh^1,2,3,4,*

Oncology Research, Vol.34, No.4, 2026, DOI:10.32604/or.2026.074144 - 23 March 2026

Abstract Objectives: Hepatocellular carcinoma (HCC) has limited systemic options with substantial toxicity. G-quadruplex (G4) structures in oncogene promoters are attractive but challenging drug targets. This study aimed to determine whether glutamic acid–chelated cobalt (GACC) is a G4-active scaffold with anti-HCC efficacy and favorable in vivo safety, and whether an AI-guided phenotypic response surface (PRS) can optimize less toxic combinations. Methods: Anticancer activity was tested in HCC cell lines (PLC/PRF/5, Hep3B, HepG2) and non-transformed THLE-2 hepatocytes (CCK-8, IC₅₀). In vivo safety/efficacy were assessed in zebrafish embryo toxicity assays, a Hep3B xenograft model, and a tert-overexpressing transgenic zebrafish model, with hepatotoxicity… More > Graphic Abstract

Saad Alobid^1,#, Hussam Albassam^1,#, Tebyan O. Mirgany², Faris Almutairi¹, Mohammed Mufadhe Alanazi¹, Ahmed H. Bakheit², Hanadi H. Asiri², Eram Eltahir³, Gamaleldin I. Harisa^3,*

Oncology Research, Vol.34, No.4, 2026, DOI:10.32604/or.2025.073371 - 23 March 2026

Abstract Objective: Glioblastoma (GB) therapy is challenged by tumor heterogeneity and multidrug resistance (MDR), highlighting the need for effective therapies. This study aimed to explore the combined anticancer effects of Sunitinib (SNB) and Fenofibrate (FEN) on U87 cells. Methods: U87 cells were exposed to SNB, FEN, or their combination for 24 h, followed by evaluations of cell viability, migration, and clonogenic survival using MTT, scratch, and colony formation assays. Intracellular reactive oxygen species (ROS) were quantified via the 2^′, 7^′-dichlorofluorescein assay, while mitochondrial membrane potential (MMP) was assessed using JC-1 red/green fluorescence. Molecular docking was performed to… More > Graphic Abstract

Maureen Veilleux^1,2,#, Anh Nguyen^3,#, Charles Cao^4,#, Yihui Shi^2,*

Oncology Research, Vol.34, No.4, 2026, DOI:10.32604/or.2026.072194 - 23 March 2026

Abstract ADP-ribosyltransferases (ARTs) regulate key processes in cancer, including DNA repair, transcription, immune responses, and treatment resistance. The clostridial toxin-like ADP-ribosyltransferase (ARTC) family and the diphtheria toxin-like ADP-ribosyltransferase (ARTD) family play a crucial role in genomic stability by modification of proteins either with mono(ADP-ribosyl)ation (MARylation) or poly(ADP-ribosyl)ation (PARylation). These ARTs are promising therapeutic targets and could serve as biomarkers in cancer management. This review explores the roles of these enzymes and current knowledge on specific inhibitors. A literature search was conducted in PubMed and Google Scholar to identify studies published between 1992 and 2025 on ADP-ribosyltransferases… More >