Pengda Niu¹, Ruidi Li^1,*, Tiechui Yuan¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.32, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.012243

Abstract In terms of grain refinement and component shape complexity, laser additive manufacturing (AM) is unmatched. This is exemplified by laser powder bed fusion (LPBF), whose rapid solidification and non-equilibrium metallurgy have expanded the understanding of ultra-fine grains and sub-stable organization among academics. At present, the reliability of LPBF components is being questioned by the industry due to the rapid heating and cooling cycles in AM processing, coupled with the extreme non-equilibrium heat-fluid-mass process, which renders LPBF printing vulnerable to metallurgical defects like microcracks and porosity. A significant impediment to the development of LPBF lies in… More >

Shouyin Zhang^1,*, Zhifeng Xu¹, Qiangwei Xiao²

The International Conference on Computational & Experimental Engineering and Sciences, Vol.32, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.012141

Abstract 3D printing sand mold has been widely used in casting production. However, there exist some problems hindering its application for titanium alloy casting, such as the large amount of gas evolution, cannot withstand high temperature impact, easy to react with titanium alloy melt, etc. This work develops a high-temperature resistance SLS (selective laser sintering) sand mold process by introducing inorganic binder in two different ways, i.e., bi-binder SLS process and SLS infiltration process. After sintering at 1100 ℃, SLS sand mold or core possesses high tensile strength and can be used for titanium alloy casting. More >

Zhen Zou^1,2, Fengxiang Xu^1,2,*, Yifan Zhu^1,2, Xiaoqiang Niu^1,2, Xiao Geng^1,2

The International Conference on Computational & Experimental Engineering and Sciences, Vol.31, No.1, pp. 1-1, 2024, DOI:10.32604/icces.2024.011093

Abstract Honeycomb cored sandwich structures have been attracted extensive attentions attributed to outstanding explosion and impact protection capability. Herein, in order to improve the anti-blast performance of re-entrant honeycombs (RH) cored sandwich panel, the conventional RH is reinforced by introducing catenary in the form of connecting both ends of horizontal cell walls and catenary. The results show that the deformation mode of the reinforced RHs (RRH) becomes more stable and regular compared to RHs, and the energy absorption of classic RHs can be enhanced because the reinforced structures and the improved auxetic deformation are employed simultaneously.… More >

Estefani S. Sugahara^1,2,3,*, André M. A. Dias^1,3, Fernanda D. Maffioletti⁵, Juarez B. Paes⁵, André L. Christoforo⁴, Edson C. Botelho², Alfredo M. P. G. Dias^1,3, Cristiane I. Campos²

Journal of Renewable Materials, Vol.12, No.11, pp. 1911-1925, 2024, DOI:10.32604/jrm.2024.056198 - 22 November 2024

Abstract Over the last decade, the oriented strand board (OSB) market presented meaningful growth. However, as a wood-based product, because of its anatomical structure and chemical composition, OSB can be damaged by biodeterioration agents. Given that, the biodeterioration of OSB panels must be investigated to improve its durability. In this way, this work analyses the biological resistance against termites (Cryptotermes brevis and Nasutitermes corniger) of heat-treated OSB panels made with Eucalyptus wood glued with vegetable-based polyurethane-an eco-friendly and sustainable adhesive derived from castor oil. Various panels were produced with different layers compositions (face:core:face of 25:50:25 and 30:40:30) in wood… More > Graphic Abstract

Muhammad Abdullah Khan¹, Muhammad Usman², Yuhong Zhao^1,3,4,*

CMC-Computers, Materials & Continua, Vol.81, No.2, pp. 1905-1952, 2024, DOI:10.32604/cmc.2024.054691 - 18 November 2024

Abstract This comprehensive review examines the structural, mechanical, electronic, and thermodynamic properties of Mg-Li-Al alloys, focusing on their corrosion resistance and mechanical performance enhancement. Utilizing first-principles calculations based on Density Functional Theory (DFT) and the quasi-harmonic approximation (QHA), the combined properties of the Mg-Li-Al phase are explored, revealing superior incompressibility, shear resistance, and stiffness compared to individual elements. The review highlights the brittleness of the alloy, supported by B/G ratios, Cauchy pressures, and Poisson’s ratios. Electronic structure analysis shows metallic behavior with varied covalent bonding characteristics, while Mulliken population analysis emphasizes significant electron transfer within the… More >

CHUAN JIANG^1,2, CHUNLEI LIU^1,3, XI YAO^1,3, JINGYA SU^1,2, WEI LU^1,3, ZHENGBO WEI^3,*, YING XIE^1,2,*

Oncology Research, Vol.32, No.12, pp. 1935-1948, 2024, DOI:10.32604/or.2024.052244 - 13 November 2024

Abstract Background: Head and neck squamous cell carcinoma (HNSCC) is a prevalent form of cancer globally, with chemoresistance posing a major challenge in treatment outcomes. The efficacy of the commonly used chemotherapeutic agent, cisplatin, is diminished in patients with poor prognoses. Methods: Various bioinformatics databases were utilized to examine Carboxylesterase 1 (CES1) gene expression, clinicopathologic features, patient survival analysis, and gene function. An organoid model of HNSCC was established, along with the induction of drug-resistant HNSCC in the organoid model. CES1 expression was assessed using qRT-PCR and Western Blot, and differential markers were identified through transcriptome… More >

YUQIN YIN^1,2,#, YU WU^1,#, HONGLIANG HUANG^1,2, YINGYING DUAN^1,2, ZHONGWEN YUAN^1,2, LIHUI CAO^1,2, JINJIN YING^1,2, YONGHENG ZHOU^3,*, SENLING FENG^1,2,*

Oncology Research, Vol.32, No.12, pp. 1891-1902, 2024, DOI:10.32604/or.2024.048778 - 13 November 2024

Abstract Background: Polymethoxylated flavones (PMFs) are compounds present in citrus peels and other Rutaceae plants, which exhibit diverse biological activities, including robust antitumor and antioxidant effects. However, the mechanism of PMFs in reversing drug resistance to colon cancer remains unknown. In the present study, we aimed to investigate the potential connection between the aerobic glycolysis-ROS-autophagy signaling axis and the reversal of PTX resistance in colon cancer by PMFs. Methods: MTT Cell viability assay and colony formation assay were used to investigate the effect of PMFs combined with PTX in reversing HCT8/T cell resistance ex vivo; the mRNA… More > Graphic Abstract

CHAOQUN WANG¹, TING ZHANG², CHAOHE ZHANG^3,*

Oncology Research, Vol.32, No.12, pp. 1867-1879, 2024, DOI:10.32604/or.2024.044547 - 13 November 2024

Abstract Background: Drug resistance is the main factor contributing to cancer recurrence and poor prognosis. Exploration of drug resistance-related mechanisms and effective therapeutic targets are the aim of molecular targeted therapy. In our study, the role of long non-coding RNA (lncRNA) AFAP1-AS1 in gemcitabine resistance and related mechanisms were explored in cervical cancer cells. Methods: Gemcitabine-resistant cervical cancer cell lines HT-3-Gem and SW756-Gem were constructed using the gemcitabine concentration gradient method. The overall survival rates and recurrence-free survival rates were evaluated by Kaplan-Meier analysis. The interaction was verified through a Dual-luciferase reporter gene assay and a… More > Graphic Abstract

Yongbing Li^1,*, Yunwu Ma¹, Yujun Xia¹, Ming Lou¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.4, pp. 1-1, 2024, DOI:10.32604/icces.2024.012602

Abstract The implementation of lightweight materials and structures in automotive body manufacturing is a strategic approach to improve fuel efficiency of energy-efficient vehicles and driving range of new energy vehicles. However, high specific strength low-ductility light metals (like 7xxx aluminum, magnesium and cast aluminum), ultra-high strength steels, high-stiffness profile structures and their mixed use poses a big challenge to existing commercial spot joining processes, such as resistance spot welding and self-piercing riveting. In this talk, the challenges which new lightweight materials and structures pose to spot joining process will be presented, the bottleneck of the existing More >

Yeye Liu¹, Leilei Zhang^1,*, Ruonan Zhang¹, Siqi Shao¹, Lina Sun¹, Xinyi Wan¹, Tiantian Wang¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.30, No.2, pp. 1-1, 2024, DOI:10.32604/icces.2024.012576

Abstract Superior thermal insulating and fire-retardant ceramic membranes are urgently demanded in the aerospace, construction and chemical engineering industries. However, the generic characteristics of ceramic membranes, such as brittleness, structural collapse and crystallization-induced pulverization behavior, present a great plague to their practical applications. Herein, we report a highly flexible, mechanically stable, fire retardant and high-temperature-resistant ceramic membrane based on the interlocked Si₃N₄ nanowires formed by the precursor pyrolysis method. The Si₃N₄ nanowires membrane (SNM) has excellent high temperature resistance under alcohol lamp and butane spray lance. The thermal insulation with a thermal conductivity as low as 0.056… More >