JIANBO ZHOU^1,2,3, FENG WAN^2,4, BIN XIAO⁵, XIN LI¹, CHENG PENG^2,*, FU PENG^1,3,*

Oncology Research, Vol.32, No.5, pp. 943-953, 2024, DOI:10.32604/or.2023.044775

Abstract Breast and lung cancers are the leading causes of mortality and most frequently diagnosed cancers in women and men, respectively, worldwide. Although the antitumor activity of chalcones has been extensively studied, the molecular mechanisms of isoliquiritigenin analog 2', 4', 4-trihydroxychalcone (metochalcone; TEC) against carcinomas remain less well understood. In this study, we found that TEC inhibited cell proliferation of breast cancer BT549 cells and lung cancer A549 cells in a concentration-dependent manner. TEC induced cell cycle arrest in the S-phase, cell migration inhibition in vitro, and reduced tumor growth in vivo. Moreover, transcriptomic analysis revealed that TEC modulated the activity… More > Graphic Abstract

Shichao Cao^*, Yonggang Dong, Xiaoying Liu

Energy Engineering, Vol.121, No.4, pp. 1109-1125, 2024, DOI:10.32604/ee.2023.043004

Abstract The synchronous virtual machine uses inverter power to imitate the performance of the conventional synchronous machine. It also has the same inertia, damping, frequency, voltage regulation, and other external performance as the generator. It is the key technology to realize new energy grid connections’ stable and reliable operation. This project studies a dynamic simulation model of an extensive new energy power system based on the virtual synchronous motor. A new energy storage method is proposed. The mathematical energy storage model is established by combining the fixed rotor model of a synchronous virtual machine with the charge-discharge power, state of charge,… More >