LU ZHANG^*, JINGUO CHU^*, YUSHAN YU

Oncology Research, Vol.32, No.4, pp. 703-716, 2024, DOI:10.32604/or.2023.030988

Abstract Background: Limited research has been conducted on the influence of autophagy-associated long non-coding RNAs (ARLncRNAs) on the prognosis of hepatocellular carcinoma (HCC). Methods: We analyzed 371 HCC samples from TCGA, identifying expression networks of ARLncRNAs using autophagy-related genes. Screening for prognostically relevant ARLncRNAs involved univariate Cox regression, Lasso regression, and multivariate Cox regression. A Nomogram was further employed to assess the reliability of Riskscore, calculated from the signatures of screened ARLncRNAs, in predicting outcomes. Additionally, we compared drug sensitivities in patient groups with differing risk levels and investigated potential biological pathways through enrichment analysis, using consensus clustering to identify subgroups… More >

Morteza Eslamian^*

Frontiers in Heat and Mass Transfer, Vol.2, No.4, pp. 1-20, 2011, DOI:10.5098/hmt.v2.4.3001

Abstract Recent advances in thermodiffusion (Soret effect) in binary and higher multicomponent liquid mixtures are reviewed. The mixtures studied include the hydrocarbon, associating, molten metal and semiconductor, polymer, and DNA mixtures. The emphasis is placed on the theoretical works, particularly models based on the nonequilibrium thermodynamics, although other approaches such as the statistical, kinetic and hydrodynamic approaches are discussed as well. For each mixture, the major theoretical and experimental works are discussed and the research trends and challenges are addressed. Some of the challenges include a need for combining various methods to develop a comprehensive theoretical model or at least to… More >

Frontiers in Heat and Mass Transfer, Vol.2, No.2, pp. 1-1, 2011, DOI:10.5098/hmt.v2.2.1001

Abstract This article has no abstract. More >

HAO LV¹, BO ZHU^1,2, DEGAO CHEN^1,2,*

BIOCELL, Vol.48, No.3, pp. 363-378, 2024, DOI:10.32604/biocell.2023.046367

Abstract Tumor-associated macrophages (TAMs) are emerging as targets for tumor therapy because of their primary role in promoting tumor progression. Several studies have been conducted to target TAMs by reducing their infiltration, depleting their numbers, and reversing their phenotypes to suppress tumor progression, leading to the development of drugs in preclinical and clinical trials. However, the heterogeneous characteristics of TAMs, including their ontogenetic and functional heterogeneity, limit their targeting. Therefore, in-depth exploration of the heterogeneity of TAMs, combined with immune checkpoint therapy or other therapeutic modalities could improve the efficiency of tumor treatment. This review focuses on the heterogeneous ontogeny and… More >

Nikola Stosic^**, Ian K. Smith, Ahmed Kovacevic

Frontiers in Heat and Mass Transfer, Vol.3, No.2, pp. 1-7, 2012, DOI:10.5098/hmt.v3.2.3003

Abstract Due to fast rotation of screw compressor rotors, temperature is uniform in the rotor cross section and temperature field is a function of the axial coordinate only. Apart of that the rotors in one cross section the rotors are simultaneously heated by hot gas on one side while cooled at another side by cold gas. As a result of identification of the main modes of heat transfer both in the rotors and between the rotors and their surroundings and the relative significance of each, a novel procedure is suggested to cool the rotors by injection of minute quantities of a… More >

Abdullah B. Alansare^*

International Journal of Mental Health Promotion, Vol.26, No.1, pp. 11-20, 2024, DOI:10.32604/ijmhp.2023.044656

Abstract Emerging evidence suggests the existence of ‘paradoxical’ relationships between domain-specific sedentary behavior (SB) and health outcomes. This study assessed the associations of total and domain-specific SB, by pattern, with symptoms of mental disorders in Saudi adults. Participants (n = 554) completed a web-based survey between January 18th, 2023 and February 5th, 2023. Total SB was measured by using the Sedentary Behavior Questionnaire. Total SB was then partitioned into leisure, occupational, and commuting SB during weekdays and on weekend days. Symptoms of mental disorders including symptoms of depression, anxiety, and stress were evaluated by using the DASS-21 questionnaire. Adjusted linear regressions… More >

Liang Zeng^1,2, Junyang Shi¹, Yanyan Li¹, Shanshan Wang^1,2,*, Weigang Li³

CMC-Computers, Materials & Continua, Vol.78, No.1, pp. 375-392, 2024, DOI:10.32604/cmc.2023.045803

Abstract The job shop scheduling problem is a classical combinatorial optimization challenge frequently encountered in manufacturing systems. It involves determining the optimal execution sequences for a set of jobs on various machines to maximize production efficiency and meet multiple objectives. The Non-dominated Sorting Genetic Algorithm III (NSGA-III) is an effective approach for solving the multi-objective job shop scheduling problem. Nevertheless, it has some limitations in solving scheduling problems, including inadequate global search capability, susceptibility to premature convergence, and challenges in balancing convergence and diversity. To enhance its performance, this paper introduces a strengthened dominance relation NSGA-III algorithm based on differential evolution… More >

Weida Wu, Yiqiang Wang, Zhonghao Gao, Pai Liu^*

CMES-Computer Modeling in Engineering & Sciences, Vol.139, No.2, pp. 2001-2026, 2024, DOI:10.32604/cmes.2023.046670

Abstract Negative Poisson’s ratio (NPR) metamaterials are attractive for their unique mechanical behaviors and potential applications in deformation control and energy absorption. However, when subjected to significant stretching, NPR metamaterials designed under small strain assumption may experience a rapid degradation in NPR performance. To address this issue, this study aims to design metamaterials maintaining a targeted NPR under large deformation by taking advantage of the geometry nonlinearity mechanism. A representative periodic unit cell is modeled considering geometry nonlinearity, and its topology is designed using a gradient-free method. The unit cell microstructural topologies are described with the material-field series-expansion (MFSE) method. The… More >

Xudong Chen^1,2, Quanzi Yuan^1,2,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.27, No.4, pp. 1-1, 2023, DOI:10.32604/icces.2023.09318

Abstract The wetting and instability of liquids on the surface of soluble solids is a problem of interface stability at multiple scales, which is coupled by mechanics and chemistry. This problem is crucial to application fields such as micro-nano processing and microscopic observation. In this work, the instability process of moving contact lines on the surfaces of soluble solids is investigated in experiments, theories, and simulations. Based on the unique shapes of the surfaces of soluble solids caused by instability in experiments, the concept of pagoda instability is proposed. Then the Cahn-Hilliard interfaces are developed to establish the evolution model of… More >

Shihao Tian^1,2, Quanzi Yuan^1,2,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.27, No.4, pp. 1-1, 2023, DOI:10.32604/icces.2023.09327

Abstract When one soluble fiber is partially merged into liquid, a meniscus forms and the fiber can be dissolved into one pinpoint with curvature. This process has been used in the manufacture of sophisticated pinpoints. However, it is hard to observe the dissolution process in the laboratory and the dissolution mechanisms are still far from being well understood in the nanoscale. Here we utilize molecular dynamics simulations to study the dissolution process of one meniscus-adhered nanofiber. We find that the tip’s curvature radius decreases and then increases, reaching the maximum in the middle state. This state is defined as the “Sh… More >