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Search Results (19)
  • Open Access

    REVIEW

    Crossroads: Pathogenic role and therapeutic targets of neutrophil extracellular traps in rheumatoid arthritis

    YANG LI1,2, JIAN LIU1,3,*, YUEDI HU1,2, CHENGZHI CONG1,2, YIMING CHEN1,2, QIAO ZHOU1,2

    BIOCELL, Vol.48, No.1, pp. 9-19, 2024, DOI:10.32604/biocell.2023.045862

    Abstract Rheumatoid arthritis (RA) is a prevalent autoimmune disease whose main features include chronic synovial inflammation, bone destruction, and joint degeneration. Neutrophils are often considered to be the first responders to inflammation and are a key presence in the inflammatory milieu of RA. Neutrophil extracellular traps (NETs), a meshwork of DNA-histone complexes and proteins released by activated neutrophils, are widely involved in the pathophysiology of autoimmune diseases, especially RA, in addition to playing a key role in the neutrophil innate immune response. NETs have been found to be an important source of citrullinated autoantigen antibodies and inflammatory factor release, which can… More > Graphic Abstract

    Crossroads: Pathogenic role and therapeutic targets of neutrophil extracellular traps in rheumatoid arthritis

  • Open Access

    ARTICLE

    Introgression of Drought Tolerance into Elite Basmati Rice Variety through Marker-Assisted Backcrossing

    Muhammad Sabar1,2,#, Shahzad Amir Naveed1,3,4,#,*, Shahid Masood Shah5, Abdul Rehman Khan5, Muhammad Musaddiq Shah6, Tahir Awan1, Muhammad Ramzan Khan3, Zaheer Abbas3, Muhammad Arif1,7,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.5, pp. 1421-1438, 2023, DOI:10.32604/phyton.2023.025801

    Abstract Drought is one of the major abiotic threat to rice production in the context of climate change. Super Basmati is an elite, fine grain basmati rice variety grown in Punjab, Pakistan. Due to drought sensitive in nature, its yield has been facing an alarming situation in production because of gradual decrease in irrigated water for a couple of years. Three reported novel QTLs for drought tolerance were selected for incorporation into Super Basmati by employing marker assisted selection strategy. IR55419-04 with novel QTLs was used as a donor parent. Foreground selection was performed by applying PCR based QTL linked SSR… More >

  • Open Access

    ARTICLE

    Physiological and Biochemical Characteristics and Response Patterns of Salinity Stress Responsive Genes (SSRGs) in Wild Quinoa (Chenopodium quinoa L.)

    Yurong Jiang1, Muhammad Yasir1, Yuefen Cao1, Lejia Hu1, Tongli Yan1, Shuijin Zhu2,*, Guoquan Lu1,*

    Phyton-International Journal of Experimental Botany, Vol.92, No.2, pp. 399-410, 2023, DOI:10.32604/phyton.2022.022742

    Abstract Cultivating salt-tolerant crops is a feasible way to effectively utilize saline-alkali land and solve the problem of underutilization of saline soils. Quinoa, a protein-comprehensive cereal in the plant kingdom, is an exceptional crop in terms of salt stress tolerance level. It seems an excellent model for the exploration of salt-tolerance mechanisms and cultivation of salt-tolerant germplasms. In this study, the seeds and seedlings of the quinoa cultivar Shelly were treated with different concentrations of NaCl solution. The physiological, biochemical characteristics and agronomic traits were investigated, and the response patterns of three salt stress-responsive genes (SSRGs) in quinoa were determined by… More >

  • Open Access

    ARTICLE

    Effect of Inclined Tension Crack on Rock Slope Stability by SSR Technique

    Ch. Venkat Ramana*, Niranjan Ramchandra Thote, Arun Kumar Singh

    Intelligent Automation & Soft Computing, Vol.36, No.1, pp. 1205-1214, 2023, DOI:10.32604/iasc.2023.031838

    Abstract The tension cracks and joints in rock or soil slopes affect their failure stability. Prediction of rock or soil slope failure is one of the most challenging tasks in the earth sciences. The actual slopes consist of inhomogeneous materials, complex morphology, and erratic joints. Most studies concerning the failure of rock slopes primarily focused on determining Factor of Safety (FoS) and Critical Slip Surface (CSS). In this article, the effect of inclined tension crack on a rock slope failure is studied numerically with Shear Strength Reduction Factor (SRF) method. An inclined Tension Crack (TC) influences the magnitude and location of… More >

  • Open Access

    ARTICLE

    Molecular characterization of sweet potato (Ipomoea batatas [L.] Lam) germplasms for desirable traits by using simple sequence repeats markers

    KHANDAKAR ABU MD MOSTAFIZAR RAHMAN1,2, ABDUL SHUKOR JURAIMI2,*, MD. REZWAN MOLLA3, MUHAMMAD ASYRAF MD HATTA4, ZULKEFLY BIN SULAIMAN5, SHAMIMA SULTANA6, AHMED GABER7, BENUKAR BISWAS8, AKBAR HOSSAIN9,*

    BIOCELL, Vol.47, No.1, pp. 227-237, 2023, DOI:10.32604/biocell.2023.025135

    Abstract Every breeding program that aims to create new and improved cultivars with desired traits mostly relies on information related to genetic diversity. Therefore, molecular characterization of germplasms is important to obtain target cultivars with desirable traits. Sweet potato [Ipomoea batatas (L.) Lam] is widely considered the world’s most important crop, with great diversity in morphological and phenotypic traits. The genetic diversity of 20 sweet potato germplasms originating from Bangladesh, CIP, Philippines, Taiwan, and Malaysia were compared, which was accomplished by genetic diversity analysis by exploring 20 microsatellite DNA markers for germplasm characterization and utilization. This information was effective in differentiating… More >

  • Open Access

    ARTICLE

    An IoT-Based Energy Conservation Smart Classroom System

    Talal H. Noor1,*, El-Sayed Atlam2, Abdulqader M. Almars1, Ayman Noor3, Amer S. Malki1

    Intelligent Automation & Soft Computing, Vol.35, No.3, pp. 3785-3799, 2023, DOI:10.32604/iasc.2023.032250

    Abstract With the increase of energy consumption worldwide in several domains such as industry, education, and transportation, several technologies played an influential role in energy conservation such as the Internet of Things (IoT). In this article, we describe the design and implementation of an IoT-based energy conservation smart classroom system that contributes to energy conservation in the education domain. The proposed system not only allows the user to access and control IoT devices (e.g., lights, projectors, and air conditions) in real-time, it also has the capability to aggregate the estimated energy consumption of an IoT device, the smart classroom, and the… More >

  • Open Access

    ARTICLE

    Identification of QTLs for Yield and Associated Traits in F2 Population of Rice

    Rohini Bhat1,*, Anil Kumar Singh2, Muntazir Mushtaq3, Romesh Kumar Salgotra2, Manmohan Sharma2, Basharat Ahmad Bhat4, Umer Basu5, Ibrahim Al-Ashkar 6, Mohammad Anwar Hossain7,*, Akihiro Ueda8, Ayman El Sabagh9

    Phyton-International Journal of Experimental Botany, Vol.91, No.11, pp. 2439-2459, 2022, DOI:10.32604/phyton.2022.020100

    Abstract Identification of quantitative trait loci (QTLs) controlling yield and yield-related traits in rice was performed in the F2 mapping population derived from parental rice genotypes DHMAS and K343. A total of 30 QTLs governing nine different traits were identified using the composite interval mapping (CIM) method. Four QTLs were mapped for number of tillers per plant on chromosomes 1 (2 QTLs), 2 and 3; three QTLs for panicle number per plant on chromosomes 1 (2 QTLs) and 3; four QTLs for plant height on chromosomes 2, 4, 5 and 6; one QTL for spikelet density on chromosome 5; four QTLs… More >

  • Open Access

    ARTICLE

    Development of polymorphic SSR markers and their applicability in genetic diversity evaluation in Euptelea pleiosperma

    XIAOJUN ZHOU*, XIAOYU LU, XUBO WANG

    BIOCELL, Vol.46, No.11, pp. 2489-2495, 2022, DOI:10.32604/biocell.2022.020311

    Abstract Euptelea pleiosperma is a characteristic species of East Asian flora with both ornamental and scientific values. Based on the reduced-representation sequencing (RRS) technology of RAD-Seq, this study conducted high-throughput Illumina paired-end sequencing to find SSR marker information in the genome of E. pleiosperma, and to screen and verify polymorphism of SSR markers. We obtained 5.5G of high-quality data using RAD-Seq. The total number of contigs of the RAD tags was 299,376, with the maximum contig length of 2,062 bp and the average length of 445 bp. From these sequences, we identified 20,718 SSR loci, with a distribution density of one… More >

  • Open Access

    ARTICLE

    Edge Detection of COVID-19 CT Image Based on GF_SSR, Improved Multiscale Morphology, and Adaptive Threshold

    Shouming Hou1, Chaolan Jia1, Kai Li1, Liya Fan2, Jincheng Guo3,*, Mackenzie Brown4,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.132, No.1, pp. 81-94, 2022, DOI:10.32604/cmes.2022.019006

    Abstract Edge detection is an effective method for image segmentation and feature extraction. Therefore, extracting weak edges with the inhomogeneous gray of Corona Virus Disease 2019 (COVID-19) CT images is extremely important. Multiscale morphology has been widely used in the edge detection of medical images due to its excellent boundary detection accuracy. In this paper, we propose a weak edge detection method based on Gaussian filtering and singlescale Retinex (GF_SSR), and improved multiscale morphology and adaptive threshold binarization (IMSM_ATB). As all the CT images have noise, we propose to remove image noise by Gaussian filtering. The edge of CT images is… More >

  • Open Access

    REVIEW

    Papaya Ring Spot Virus: An Understanding of a Severe Positive-Sense Single Stranded RNA Viral Disease and Its Management

    Muhammad Umer1, Mustansar Mubeen2, Yasir Iftikhar2,*, Haider Ali3, Muhammad Zafar-ul-Hye4, Rafia Asghar5, Mazhar Abbas6, Malik Abdul Rehman7, Ernesto A. Moya-Elizondo8, Yuejun He1,*

    Phyton-International Journal of Experimental Botany, Vol.91, No.10, pp. 2099-2110, 2022, DOI:10.32604/phyton.2022.022013

    Abstract Viral diseases have been studied in-depth for reducing quality, yield, health and longevity of the fruit, to highlight the economic losses. Positive-sense single-stranded RNA viruses are more devastating among all viruses that infect fruit trees. One of the best examples is papaya ringspot virus (PRSV). It belongs to the genus Potyvirus and it is limited to cause diseases on the family Chenopodiaceae, Cucurbitaceae and Caricaceae. This virus has a serious threat to the production of papaya, which is famous for its high nutritional and pharmaceutical values. The plant parts such as leaves, latex, seeds, fruits, bark, peel and roots may… More >

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