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    REVIEW

    Cell cycle regulation through primary cilium: A long-forgotten story

    LIN LIU, ZHOUWEN XU, YUYAN JIANG, MD REZAUL KARIM, XIAO HUANG*

    BIOCELL, Vol.45, No.4, pp. 823-833, 2021, DOI:10.32604/biocell.2021.013864

    Abstract Protruded from cytomembrane, primary cilium is a widespread cell organelle that can be found in almost all cell types in Mammalia. Because of its comprehensive requirement in various cellular activities and various functions in different organs, primary cilium has been a valuable research area of human pathology research since the turn of the millennium. And the potential application of the interaction between primary cilia and cell cycle regulation may be the most promising direction as many primary cilium-caused diseases are found to be caused by cell cycle dysregulation resulted from primary cilia defects. Therefore, a deep understanding of the interaction… More >

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