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  • Open Access

    ARTICLE

    Missing Value Imputation for Radar-Derived Time-Series Tracks of Aerial Targets Based on Improved Self-Attention-Based Network

    Zihao Song, Yan Zhou*, Wei Cheng, Futai Liang, Chenhao Zhang

    CMC-Computers, Materials & Continua, Vol.78, No.3, pp. 3349-3376, 2024, DOI:10.32604/cmc.2024.047034

    Abstract The frequent missing values in radar-derived time-series tracks of aerial targets (RTT-AT) lead to significant challenges in subsequent data-driven tasks. However, the majority of imputation research focuses on random missing (RM) that differs significantly from common missing patterns of RTT-AT. The method for solving the RM may experience performance degradation or failure when applied to RTT-AT imputation. Conventional autoregressive deep learning methods are prone to error accumulation and long-term dependency loss. In this paper, a non-autoregressive imputation model that addresses the issue of missing value imputation for two common missing patterns in RTT-AT is proposed. Our model consists of two… More >

  • Open Access

    ARTICLE

    Kaempferol ameliorated levodopa-induced dyskinesia in experimental rats: A role of brain monoamines, cFOS, FosB, Parkin, Pdyn, TH, and p-JNK

    PEI QIN#, MIAO LIU#, XIN WANG, JIANHUA MA*

    BIOCELL, Vol.48, No.3, pp. 513-523, 2024, DOI:10.32604/biocell.2023.045640

    Abstract Background: L-dopa (Levodopa) is well known for managing PD (Parkinson’s disease); however, its prolonged use caused dyskinesia (LID). Due to the varied presentation of LID, effective treatment options are scarce. Flavonoids reported their neuroprotective activity by ameliorating acetylcholinesterase, monoamine oxidase, and neuroinflammation. Kaempferol is another flavonoid bearing these potentials. Aim: To evaluate neuroprotective activity of kaempferol in dyskinetic rats. Methods: PD was developed in Sprague-Dawley rats by injecting combination of L-ascorbic acid (10 µL) + 6-OHDA (12 µg) in medial forebrain bundle to induce neuronal damage in substantial nigra (SNr). LID was induced by administrating combination of L-dopa (20 mg/kg)… More > Graphic Abstract

    Kaempferol ameliorated levodopa-induced dyskinesia in experimental rats: A role of brain monoamines, cFOS, FosB, Parkin, Pdyn, TH, and p-JNK

  • Open Access

    ARTICLE

    Smart MobiNet: A Deep Learning Approach for Accurate Skin Cancer Diagnosis

    Muhammad Suleman1, Faizan Ullah1, Ghadah Aldehim2,*, Dilawar Shah1, Mohammad Abrar1,3, Asma Irshad4, Sarra Ayouni2

    CMC-Computers, Materials & Continua, Vol.77, No.3, pp. 3533-3549, 2023, DOI:10.32604/cmc.2023.042365

    Abstract The early detection of skin cancer, particularly melanoma, presents a substantial risk to human health. This study aims to examine the necessity of implementing efficient early detection systems through the utilization of deep learning techniques. Nevertheless, the existing methods exhibit certain constraints in terms of accessibility, diagnostic precision, data availability, and scalability. To address these obstacles, we put out a lightweight model known as Smart MobiNet, which is derived from MobileNet and incorporates additional distinctive attributes. The model utilizes a multi-scale feature extraction methodology by using various convolutional layers. The ISIC 2019 dataset, sourced from the International Skin Imaging Collaboration,… More >

  • Open Access

    ARTICLE

    Analysis of differentially expressed genes in Verruca vulgaris vs. adjacent normal skin by RNA-sequencing

    QINGQING GUO1,2, JIAYUE QI1,2, XIAOQIANG LIANG2, ZIGANG ZHAO2, JIA BAI2, FANG XIE2,#,*, CHENGXIN LI1,2,#,*

    BIOCELL, Vol.47, No.11, pp. 2435-2443, 2023, DOI:10.32604/biocell.2023.043126

    Abstract Introduction: Verruca vulgaris is one of the most common low-risk HPV infections and is characterized by excessive proliferation of keratinocytes. Currently, very little genetic information is available regarding verruca vulgaris in the Chinese population. This study aimed to obtain comprehensive transcript information of verruca vulgaris by RNA sequencing. Methods: High-throughput sequencing was performed on three fresh verruca vulgaris samples and adjacent normal skin on the Illumina sequencing platform. The transcriptomes were analyzed using bioinformatics and the differentially expressed genes (DEGs) were verified by immunohistochemistry. Verruca vulgaris exhibited a unique molecular signature. Results: In total, 1,643 DEGs were identified in verruca… More >

  • Open Access

    ARTICLE

    Deep Learning-Based Stacked Auto-Encoder with Dynamic Differential Annealed Optimization for Skin Lesion Diagnosis

    Ahmad Alassaf*

    Computer Systems Science and Engineering, Vol.47, No.3, pp. 2773-2789, 2023, DOI:10.32604/csse.2023.035899

    Abstract Intelligent diagnosis approaches with shallow architectural models play an essential role in healthcare. Deep Learning (DL) models with unsupervised learning concepts have been proposed because high-quality feature extraction and adequate labelled details significantly influence shallow models. On the other hand, skin lesion-based segregation and disintegration procedures play an essential role in earlier skin cancer detection. However, artefacts, an unclear boundary, poor contrast, and different lesion sizes make detection difficult. To address the issues in skin lesion diagnosis, this study creates the UDLS-DDOA model, an intelligent Unsupervised Deep Learning-based Stacked Auto-encoder (UDLS) optimized by Dynamic Differential Annealed Optimization (DDOA). Pre-processing, segregation,… More >

  • Open Access

    REVIEW

    Possible therapeutic role of short-chain fatty acids from skin commensal bacteria in UVB-induced skin carcinogenesis

    PAVITHRA SUBRAMANI1,2, RAUNAK KUMAR DAS1,*

    BIOCELL, Vol.47, No.10, pp. 2195-2205, 2023, DOI:10.32604/biocell.2023.030383

    Abstract Solar ultraviolet B (UVB) radiation is a major skin cancer-causing agent. Initiation, promotion, and progression are the diverse phases of UVB-induced carcinogenesis. Exposure to UVB causes abnormalities in a series of biochemical and molecular pathways: thymine dimer formation, DNA damage, oxidative stress, inflammatory responses, and altered cell signaling, eventually resulting in tumor formation. The increased skin cancer rates urge researchers to develop more efficient drugs, but synthetic chemotherapeutic drugs have more contrary effects and drug resistance issues, which have been reported recently. The current review focuses on the relationship between microbes and cancer. Human skin acts as a barrier against… More > Graphic Abstract

    Possible therapeutic role of short-chain fatty acids from skin commensal bacteria in UVB-induced skin carcinogenesis

  • Open Access

    ARTICLE

    Sand Cat Swarm Optimization with Deep Transfer Learning for Skin Cancer Classification

    C. S. S. Anupama1, Saud Yonbawi2, G. Jose Moses3, E. Laxmi Lydia4, Seifedine Kadry5,6,7, Jungeun Kim8,*

    Computer Systems Science and Engineering, Vol.47, No.2, pp. 2079-2095, 2023, DOI:10.32604/csse.2023.038322

    Abstract Skin cancer is one of the most dangerous cancer. Because of the high melanoma death rate, skin cancer is divided into non-melanoma and melanoma. The dermatologist finds it difficult to identify skin cancer from dermoscopy images of skin lesions. Sometimes, pathology and biopsy examinations are required for cancer diagnosis. Earlier studies have formulated computer-based systems for detecting skin cancer from skin lesion images. With recent advancements in hardware and software technologies, deep learning (DL) has developed as a potential technique for feature learning. Therefore, this study develops a new sand cat swarm optimization with a deep transfer learning method for… More >

  • Open Access

    ARTICLE

    NUMERICAL SIMULATION OF A DOUBLE SKIN WITH SECONDARY VENTILATION FLOW ON ADIABATIC WALL

    M. Bouraouia, M. S. Rouabaha, A. Abidi-Saadb,c,d,*, A. Korichie, C. Popab , G. Polidorib

    Frontiers in Heat and Mass Transfer, Vol.8, pp. 1-6, 2017, DOI:10.5098/hmt.8.18

    Abstract Study concerning a double skin flow with secondary ventilation was conducted numerically, in order to understand the basic mechanisms of the free convection in an open channel asymmetrically heated with uniform heat flux density (510 W/m2 ). The vertical channel corresponds to a double skin façade, which was immersed in a tank filled with water. The tank corresponds to the environment which allows us to overcome pressure conditions at the inlet and the outlet of the channel. The use of water allows neglecting radiation effect. The mass conservation equations of momentum and energy are solved using the finite volume method… More >

  • Open Access

    ARTICLE

    MHD SLIP FLOW AND HEAT TRANSFER OVER AN EXPONENTIALLY STRETCHING PERMEABLE SHEET EMBEDDED IN A POROUS MEDIUM WITH HEAT SOURCE

    P. R. Sharmaa , Sushila Choudharya,* , O. D. Makindeb

    Frontiers in Heat and Mass Transfer, Vol.9, pp. 1-7, 2017, DOI:10.5098/hmt.9.18

    Abstract Steady two dimensional laminar magnetohydrodynamic (MHD) slip flow and heat transfer of a viscous incompressible and electrically conducting fluid past over a flat exponentially non-conducting stretching porous sheet embedded in a porous medium with non uniform permeability in the presence of non uniform heat source is investigated. The governing equations of velocity and temperature distributions are solved numerically and the effects of different physical parameters are shown through graphs. The rate of shear stress and the rate of heat transfer at the sheet are derived, discussed numerically and their numerical values for various values of physical parameters are presented through… More >

  • Open Access

    ARTICLE

    NUMERICAL STUDY OF NON-NEWTONIAN POLYMERIC BOUNDARY LAYER FLOW AND HEAT TRANSFER FROM A PERMEABLE HORIZONTAL ISOTHERMAL CYLINDER

    A. Subba Raoa,* , V. Ramachandra Prasada , P. Rajendraa , M. Sasikalaa , O. Anwar Begb

    Frontiers in Heat and Mass Transfer, Vol.9, pp. 1-9, 2017, DOI:10.5098/hmt.9.2

    Abstract In this article, we investigate the nonlinear steady state boundary layer flow and heat transfer of an incompressible Jeffery non-Newtonian fluid from a permeable horizontal isothermal cylinder. The transformed conservation equations are solved numerically subject to physically appropriate boundary conditions using a versatile, implicit, finite-difference technique. The numerical code is validated with previous studies. The influence of a number of emerging non-dimensional parameters, namely with Deborah number (De), surface suction parameter (S), Prandtl number (Pr), ratio of relaxation to retardation times (λ) and dimensionless tangential coordinate (ξ) on velocity and temperature evolution in the boundary layer regime are examined in… More >

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