YUTING WANG1,2,3, PEIWEN FAN1,2,3, YANING FENG1,2,3, XUAN YAO4, YANCHUN PENG4, RUOZHENG WANG1,2,3,*
BIOCELL, Vol.47, No.6, pp. 1365-1375, 2023, DOI:10.32604/biocell.2023.027201
Abstract Background: This study was designed to investigate the feasibility of tumor-infiltrating immune cells with
different phenotypic characteristics for predicting short-term clinical responses in patients with locally advanced
cervical cancer (LACC). Methods: Thirty-four patients who received concurrent chemoradiotherapy and twenty-one
patients who merely underwent radiotherapy were enrolled in this study. We retrospectively analyzed the T cell
markers (i.e., CD3, CD4, CD8), memory markers (i.e., CD45, CCR7), and differentiation markers (i.e., CD27) in the
peripheral blood and tumor tissues of patients with LACC before treatment based on flow cytometry. We also
analyzed the relationship of T cell subsets between peripheral blood and… More >
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