Jiangyang Yuan¹, Jiaowen Wu¹, Yi Gao¹, Yuhao Fu², Yuntao Bu², Tianyu Chen², Hao Yu^2,*

Energy Engineering, Vol.123, No.2, 2026, DOI:10.32604/ee.2025.070715 - 27 January 2026

Abstract In the pursuit of carbon peaking and neutrality goals, multi-energy parks, as major energy consumers and carbon emitters, urgently require low-carbon operational strategies. This paper proposes an electricity-carbon synergy-driven optimization method for the low-carbon operation of multi-energy parks. The method integrates multi-energy complementary scheduling with a tiered carbon trading mechanism to balance operational security, economic efficiency, and environmental objectives. A mixed-integer linear programming model is developed to characterize the coupling relationships and dynamic behaviors of key equipment, including photovoltaic systems, ground-source heat pumps, thermal storage electric boilers, combined heat and power units, and electrical energy… More >

Junxian Ma¹, Haonan Zhao^2,*, Zhibing Hu³, Yaru Shen³, Fan Ding³, Shouqi Jiang²

Energy Engineering, Vol.123, No.2, 2026, DOI:10.32604/ee.2025.070530 - 27 January 2026

Abstract Energy storage-equipped photovoltaic (PV-storage) systems can meet frequency regulation requirements under various operating conditions, and their coordinated support for grid frequency has become a future trend. To address frequency stability issues caused by low inertia and weak damping, this paper proposes a multi-timescale frequency regulation coordinated control strategy for PV-storage integrated systems. First, a self-synchronizing control strategy for grid-connected inverters is designed based on DC voltage dynamics, enabling active inertia support while transmitting frequency variation information. Next, an energy storage inertia support control strategy is developed to enhance the frequency nadir, and an active frequency… More >

Chenxuan Zhang, Yongqing Qi^*, Ximin Cao, Yanchi Zhang

Energy Engineering, Vol.123, No.2, 2026, DOI:10.32604/ee.2025.069878 - 27 January 2026

Abstract To enhance the low-carbon economic efficiency and increase the utilization of renewable energy within integrated energy systems (IES), this paper proposes a low-carbon dispatch model integrating power-to-gas (P2G), carbon capture and storage (CCS), hydrogen fuel cell (HFC), and combined heat and power (CHP). The P2G process is refined into a two-stage structure, and HFC is introduced to enhance hydrogen utilization. Together with CCS and CHP, these devices form a multi-energy conversion system coupling electricity, heat, cooling, and gas. A ladder-type carbon trading approach is adopted to flexibly manage carbon output by leveraging marginal cost adjustments.… More >

Hongsheng Su, Zhensheng Teng^*, Zihan Zhou

Energy Engineering, Vol.123, No.2, 2026, DOI:10.32604/ee.2025.069495 - 27 January 2026

Abstract Addressing the limitations of inadequate stochastic disturbance characterization during wind turbine degradation processes that result in constrained modeling accuracy, replacement-based maintenance practices that deviate from actual operational conditions, and static maintenance strategies that fail to adapt to accelerated deterioration trends leading to suboptimal remaining useful life utilization, this study proposes a Time-Based Incomplete Maintenance (TBIM) strategy incorporating reliability constraints through stochastic differential equations (SDE). By quantifying stochastic interference via Brownian motion terms and characterizing nonlinear degradation features through state influence rate functions, a high-precision SDE degradation model is constructed, achieving 16% residual reduction compared to… More >

SHAOFENG XIONG^1,2, WENKAI LV³, GUOSHENG CAO⁴, LONGSHENG FU¹, WEN LIU³, MENGFAN LEI², YANNI LV^1,5,*

BIOCELL, Vol.50, No.1, 2026, DOI:10.32604/biocell.2025.073401 - 23 January 2026

Abstract Objective: Leucine-rich alpha-2 glycoprotein 1 (Lrg1) could regulate diverse cells in cerebral ischemia-reperfusion. Our study seeks to uncover Lrg1’s impact on endothelial cell heterogeneity via differentiation pathways and transcription factors. Method: The CSOmap model measured cell-to-brain-center distances using single-cell RNA sequencing (scRNA-seq) data in middle cerebral artery occlusion reperfusion (MCAO/R). Monocle2 mapped endothelial differentiation paths. Gene set enrichment analysis (GSEA) analyzed endothelial subcluster variations. Database searches revealed a zinc finger MIZ-type containing 1 protein-frizzled 3 (Zmiz1-Fzd3) promoter interaction. Endothelial cells were transfected with a Fzd3 promoter-luciferase plasmid. Polymerase chain reaction (PCR) and western blotting assessed… More >

Douglas M. Ruden^*

BIOCELL, Vol.50, No.1, 2026, DOI:10.32604/biocell.2025.072273 - 23 January 2026

Abstract Stem cell fate decisions are increasingly understood through the dynamic interplay of two fundamental stress-adaptive programs: the integrated stress response (ISR) and the senescence-associated secretory phenotype (SASP). These pathways act as a Yin–Yang system, balancing beneficial and detrimental outcomes across development, tissue homeostasis, and disease. On the yin (protective) side, transient ISR activation and acute SASP signaling foster adaptation, embryonic patterning, wound healing, and regeneration. On the yang (maladaptive) side, chronic ISR signaling and unresolved SASP output drive stem cell exhaustion, fibrosis, inflammation, and tumorigenesis. This duality highlights their roles as both guardians and disruptors More > Graphic Abstract

Jiale Hu, Fan Chen^*, Yue Yang, Man Wang

Journal on Artificial Intelligence, Vol.8, pp. 51-64, 2026, DOI:10.32604/jai.2026.075257 - 22 January 2026

Abstract To enhance the operational performance of energy storage systems (ESS), this paper proposes an optimal dispatch strategy that jointly considers reliability and economic efficiency. First, we formulate a cost-minimization model that includes ESS dispatch costs, wind and photovoltaic (PV) curtailment costs, and load loss costs, while explicitly enforcing power supply reliability constraints. Next, we develop a comprehensive evaluation indicator system that integrates reliability, economic performance, renewable-energy utilization, and ESS technical indicators, thereby addressing the limitations of single-indicator assessments. Finally, a case study using real data from a region in China shows that the proposed strategy More >

Xiaoyu Zhang^1,#, RenFei Zong^1,#, Yan Sun¹, Nan Chen², Kunyao Zhu¹, Hang Tong¹, Tinghao Li¹, Junlong Zhu¹, Zijia Qin¹, Linfeng Wu¹, Aimin Wang¹, Weiyang He^1,*

Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.072084 - 19 January 2026

Abstract Objective: While cisplatin-based chemotherapy is pivotal for advanced bladder cancer, acquired resistance remains a major obstacle. This study investigates key molecular drivers of this resistance and potential reversal strategies. Methods: We established GC (Gemcitabine and Cisplatin)-resistant T24-R and UC3-R cell lines from T24 and UM-UC-3 (UC3) cells. Transcriptomic and proteomic analyses identified differentially expressed molecules. Apoptosis and cell viability were assessed by flow cytometry and CCK-8 (Cell Counting Kit-8) assays, while RT-qPCR (Reverse Transcription Quantitative Polymerase Chain Reaction) and Western blot analyzed gene and protein expression. Immunofluorescence evaluated FAK (Focal Adhesion Kinase) phosphorylation, and a… More >

Marta Pawłowska^1,*, Dorian Jarek², Jan Milanowski², Karolina Szewczyk-Golec¹

Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.071891 - 19 January 2026

Abstract Parasitic infections are increasingly recognized as contributors to cancer development, yet the underlying oncogenic mechanisms remain insufficiently understood. Growing evidence from molecular oncology, immunology, and microbiome research suggests that chronic parasitic infections may drive tumorigenesis through sustained inflammation, deregulated signaling pathways, genomic instability, and the release of parasite-derived exosomes that reshape the tumor microenvironment. These insights underscore the need to integrate parasitology with cancer biology to understand infection-associated malignancies better. The aim of this narrative review is to synthesize current knowledge on how selected parasites contribute to cancer development and to highlight emerging therapeutic and… More > Graphic Abstract

Min Hee Kim¹, Boyoon Huh¹, Joo-Won Park^1,*, Woo-Jae Park^2,*

Oncology Research, Vol.34, No.2, 2026, DOI:10.32604/or.2025.071523 - 19 January 2026

Abstract Breast cancer is one of the most prevalent malignancies among women and comprises a heterogeneous spectrum of molecular subtypes with distinct biological behaviors. Among various regulatory molecules, sphingolipids play pivotal roles in dynamically modulating fundamental cellular processes such as proliferation, apoptosis, and metastasis through metabolic interconversions, including phosphorylation, glycosylation, and the generation of sphingosine-1-phosphate. This review aims to elucidate the mechanisms through which sphingolipid metabolism orchestrates cancer cell fate and drives breast cancer progression. Particular emphasis is placed on the balance between proapoptotic ceramides and pro-survival metabolites, such as sphingosine-1-phosphate, which collectively influence tumor growth More >