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  • Open Access

    ARTICLE

    Explainable Diabetic Retinopathy Detection Using a Distributed CNN and LightGBM Framework

    Pooja Bidwai1,2, Shilpa Gite1,3, Biswajeet Pradhan4,*, Abdullah Almari5

    CMC-Computers, Materials & Continua, Vol.84, No.2, pp. 2645-2676, 2025, DOI:10.32604/cmc.2025.061018 - 03 July 2025

    Abstract Diabetic Retinopathy (DR) is a critical disorder that affects the retina due to the constant rise in diabetics and remains the major cause of blindness across the world. Early detection and timely treatment are essential to mitigate the effects of DR, such as retinal damage and vision impairment. Several conventional approaches have been proposed to detect DR early and accurately, but they are limited by data imbalance, interpretability, overfitting, convergence time, and other issues. To address these drawbacks and improve DR detection accurately, a distributed Explainable Convolutional Neural network-enabled Light Gradient Boosting Machine (DE-ExLNN) is… More >

  • Open Access

    REVIEW

    ChatGPT in Research and Education: A SWOT Analysis of Its Academic Impact

    Abu Saleh Musa Miah1, Md Mahbubur Rahman Tusher2, Md. Moazzem Hossain2, Md Mamun Hossain2, Md Abdur Rahim3, Md Ekramul Hamid4, Md. Saiful Islam4, Jungpil Shin1,*

    CMES-Computer Modeling in Engineering & Sciences, Vol.143, No.3, pp. 2573-2614, 2025, DOI:10.32604/cmes.2025.064168 - 30 June 2025

    Abstract Advanced artificial intelligence technologies such as ChatGPT and other large language models (LLMs) have significantly impacted fields such as education and research in recent years. ChatGPT benefits students and educators by providing personalized feedback, facilitating interactive learning, and introducing innovative teaching methods. While many researchers have studied ChatGPT across various subject domains, few analyses have focused on the engineering domain, particularly in addressing the risks of academic dishonesty and potential declines in critical thinking skills. To address this gap, this study explores both the opportunities and limitations of ChatGPT in engineering contexts through a two-part… More >

  • Open Access

    ARTICLE

    TGI-FPR: An Improved Multi-Label Password Guessing Model

    Wei Ou1,2,3, Shuai Liu1,*, Mengxue Pang1, Jianqiang Ma1, Qiuling Yue1, Wenbao Han1

    CMC-Computers, Materials & Continua, Vol.84, No.1, pp. 463-490, 2025, DOI:10.32604/cmc.2025.063862 - 09 June 2025

    Abstract TarGuess-I is a leading model utilizing Personally Identifiable Information for online targeted password guessing. Due to its remarkable guessing performance, the model has drawn considerable attention in password security research. However, through an analysis of the vulnerable behavior of users when constructing passwords by combining popular passwords with their Personally Identifiable Information, we identified that the model fails to consider popular passwords and frequent substrings, and it uses overly broad personal information categories, with extensive duplicate statistics. To address these issues, we propose an improved password guessing model, TGI-FPR, which incorporates three semantic methods: (1) More >

  • Open Access

    ARTICLE

    Leveraging AI for Advancements in Qualitative Research Methodology

    Ilyas Haouam*

    Journal on Artificial Intelligence, Vol.7, pp. 85-114, 2025, DOI:10.32604/jai.2025.064145 - 27 May 2025

    Abstract This study investigates the integration of Artificial Intelligence (AI) technologies—particularly natural language processing and machine learning—into qualitative research (QR) workflows. Our research demonstrates that AI can streamline data collection, coding, theme identification, and visualization, significantly improving both speed and accuracy compared to traditional manual methods. Notably, our experimental and numerical results provide a comprehensive analysis of AI’s effect on efficiency, accuracy, and usability across various QR tasks. By presenting and discussing studies on some AI & generative AI models, we contribute to the ongoing scholarly discussion on the role of AI in QR exploring its… More >

  • Open Access

    REVIEW

    In Search of New Pharmacological Targets: Beyond Carnosine’s Antioxidant, Anti-Inflammatory, and Anti-Aggregation Activities

    Giuseppe Carota1, Lucia Di Pietro2,3, Vincenzo Cardaci4, Anna Privitera1,2, Francesco Bellia1, Valentina Di Pietro5, Giuseppe Lazzarino1, Barbara Tavazzi6, Angela Maria Amorini1, Giacomo Lazzarino6, Giuseppe Caruso6,7,*

    BIOCELL, Vol.49, No.4, pp. 563-578, 2025, DOI:10.32604/biocell.2025.062176 - 30 April 2025

    Abstract Carnosine (β-alanyl-L-histidine) is a naturally occurring endogenous peptide widely distributed in excitable tissues, such as the heart and brain. Over the years, several beneficial effects of carnosine have been discussed well in scientific literature. In particular, this dipeptide is well-known for its antioxidant, anti-inflammatory, and anti-aggregation activities. It is of great interest in the context of numerous systemic and neurodegenerative diseases, besides performing important “side activities” such as metal chelation and pH-buffering. Despite a plethora of preclinical and clinical data supporting carnosine’s therapeutic potential, researchers are still searching for new pharmacological targets that better highlight More >

  • Open Access

    ARTICLE

    Deep Learning-Based Decision Support System for Predicting Pregnancy Risk Levels through Cardiotocograph (CTG) Imaging Analysis

    Ali Hasan Dakheel1,*, Mohammed Raheem Mohammed1, Zainab Ali Abd Alhuseen1, Wassan Adnan Hashim2,3

    Intelligent Automation & Soft Computing, Vol.40, pp. 195-220, 2025, DOI:10.32604/iasc.2025.061622 - 28 February 2025

    Abstract The prediction of pregnancy-related hazards must be accurate and timely to safeguard mother and fetal health. This study aims to enhance risk prediction in pregnancy with a novel deep learning model based on a Long Short-Term Memory (LSTM) generator, designed to capture temporal relationships in cardiotocography (CTG) data. This methodology integrates CTG signals with demographic characteristics and utilizes preprocessing techniques such as noise reduction, normalization, and segmentation to create high-quality input for the model. It uses convolutional layers to extract spatial information, followed by LSTM layers to model sequences for superior predictive performance. The overall More >

  • Open Access

    ARTICLE

    CYB5D2 inhibits the malignant progression of hepatocellular carcinoma by inhibiting TGF-β expression and epithelial-mesenchymal transition

    DONG JIANG1, ZHI QI3, ZHIYING XU2,*, YIRAN LI1,*

    Oncology Research, Vol.33, No.3, pp. 709-722, 2025, DOI:10.32604/or.2024.050125 - 28 February 2025

    Abstract Background: Hepatocellular carcinoma (HCC) is a prevalent liver malignancy. This study examined the roles of transforming growth factor beta (TGF-β) and cytochrome b5 domain containing 2 (CYB5D2) in HCC etiology and their prognostic biomarker potential. Methods: Key modules and prognostic genes were identified by analyzing the GSE101685 dataset by weighted gene co-expression network analysis (WGCNA) and Least absolute shrinkage and selection operator (LASSO) Cox regression. The expression levels of CYB5D2 and TGF-β in HCC cell lines were quantified using Quantitative reverse transcription polymerase chain reaction (qRT-PCR) and Western blotting (WB) assays. Effects of CYB5D2 overexpression on cell proliferation,… More >

  • Open Access

    ARTICLE

    MSSTGCN: Multi-Head Self-Attention and Spatial-Temporal Graph Convolutional Network for Multi-Scale Traffic Flow Prediction

    Xinlu Zong*, Fan Yu, Zhen Chen, Xue Xia

    CMC-Computers, Materials & Continua, Vol.82, No.2, pp. 3517-3537, 2025, DOI:10.32604/cmc.2024.057494 - 17 February 2025

    Abstract Accurate traffic flow prediction has a profound impact on modern traffic management. Traffic flow has complex spatial-temporal correlations and periodicity, which poses difficulties for precise prediction. To address this problem, a Multi-head Self-attention and Spatial-Temporal Graph Convolutional Network (MSSTGCN) for multiscale traffic flow prediction is proposed. Firstly, to capture the hidden traffic periodicity of traffic flow, traffic flow is divided into three kinds of periods, including hourly, daily, and weekly data. Secondly, a graph attention residual layer is constructed to learn the global spatial features across regions. Local spatial-temporal dependence is captured by using a More >

  • Open Access

    ARTICLE

    Automation of Software Development Stages with the OpenAI API

    Verónica C. Tapia1,2,*, Carlos M. Gaona2

    Computer Systems Science and Engineering, Vol.49, pp. 1-17, 2025, DOI:10.32604/csse.2024.056979 - 03 January 2025

    Abstract In recent years, automation has become a key focus in software development as organizations seek to improve efficiency and reduce time-to-market. The integration of artificial intelligence (AI) tools, particularly those using natural language processing (NLP) like ChatGPT, has opened new possibilities for automating various stages of the development lifecycle. The primary objective of this study is to evaluate the effectiveness of ChatGPT in automating various phases of software development. An artificial intelligence (AI) tool was developed using the OpenAI—Application Programming Interface (API), incorporating two key functionalities: 1) generating user stories based on case or process… More >

  • Open Access

    ARTICLE

    Long noncoding RNA LINC01106 promotes lung adenocarcinoma progression via upregulation of autophagy

    GENGYUN SUN1,*, YIPING ZHENG1,2, JIANFENG CAI2, JIE GAO2, LIE DONG2, XIANGBIN ZHANG2, YINGHUI HUANG2,*

    Oncology Research, Vol.33, No.1, pp. 171-184, 2025, DOI:10.32604/or.2024.047626 - 20 December 2024

    Abstract Background: Long noncoding RNA, LINC01106 exhibits high expression in lung adenocarcinoma (LUAD) tumor tissues, but its functional role and regulatory mechanism in LUAD cells remain unclear. Methods: LINC01106 expression was analyzed in LUAD tissues and its functional impact on LUAD cells was assessed. LUAD cells were silenced with sh-LINC01106 and injected into nude mice to investigate tumor growth. The downstream transcription factors and molecular mechanism were determined using the Human transcription factor database (TFDB) database and Gene Expression Profiling Interactive Analysis (GEPIA) database. Additionally, the impact of linc01106 on autophagy was analyzed by determining the… More > Graphic Abstract

    Long noncoding RNA LINC01106 promotes lung adenocarcinoma progression via upregulation of autophagy

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