FEI CHU¹, KAI TONG¹, XIANG GU¹, MEI BAO¹, YANFEN CHEN¹, BIN WANG², YANHUA SHAO¹, LING WEI^1,*

Oncology Research, Vol.32, No.10, pp. 1661-1671, 2024, DOI:10.32604/or.2024.048287

Abstract Glutamine is one of the most abundant non-essential amino acids in human plasma and plays a crucial role in many biological processes of the human body. Tumor cells take up a large amount of glutamine to meet their rapid proliferation requirements, which is supported by the upregulation of glutamine transporters. Targeted inhibition of glutamine transporters effectively inhibits cell growth and proliferation in tumors. Among all cancers, digestive system malignant tumors (DSMTs) have the highest incidence and mortality rates, and the current therapeutic strategies for DSMTs are mainly surgical resection and chemotherapy. Due to the relatively More > Graphic Abstract

Benxin Li^*, Xuanming Chang

Energy Engineering, Vol.121, No.10, pp. 3001-3018, 2024, DOI:10.32604/ee.2024.051332

Abstract The increasingly large number of electric vehicles (EVs) has resulted in a growing concern for EV charging station load prediction for the purpose of comprehensively evaluating the influence of the charging load on distribution networks. To address this issue, an EV charging station load prediction method is proposed in coupled urban transportation and distribution networks. Firstly, a finer dynamic urban transportation network model is formulated considering both nodal and path resistance. Then, a finer EV power consumption model is proposed by considering the influence of traffic congestion and ambient temperature. Thirdly, the Monte Carlo method… More > Graphic Abstract

ZULONG SHENG^*, YANRU HE, JUNYAN CAI, YUQIN JI, YUYU YAO, GENSHAN MA

BIOCELL, Vol.48, No.9, pp. 1369-1377, 2024, DOI:10.32604/biocell.2024.049905

Abstract Background: Myocardial infarction (MI) is known worldwide for its important disabling features, including myocarditis and cardiomyocyte apoptosis. It is believed that microRNA (miRNA) has a role in the cellular processes of apoptosis and myocarditis, and miR-219a-5p has been found to suppress the inflammatory response. However, unknown is the precise mechanism by which miR-219a-5p contributes to MI. Methods: We measured the expression of miR-219a-5p and evaluated its effects on target proteins, inflammatory factors, and apoptosis in a mouse model of MI. Echocardiography was utilized to examine the MI clinical index, and triphenyl tetrazolium chloride staining was More >

Haowei Hu^1,2,*, Qi Wang¹, Xinnuo Chen¹, Qin Li³, Mu Du⁴, Dong Niu^5,*

Frontiers in Heat and Mass Transfer, Vol.22, No.4, pp. 1245-1259, 2024, DOI:10.32604/fhmt.2024.054223

Abstract To investigate the microscopic mechanism underlying the influence of surface-chemical gradient on heat and mass recovery, a molecular dynamics model including droplet condensation and transport process has been developed to examine heat and mass recovery performance. This work aimed at identify optimal conditions for enhancing heat and mass recovery through the combination of wettability gradient and nanopore transport. For comprehensive analysis, the structure in the simulation was categorized into three distinct groups: a homogeneous structure, a small wettability gradient, and a large wettability gradient. The homogeneous surface demonstrated low efficiency in heat and mass transfer, More >

Zhenzhen Liu, Hua Zhang^*, Zilong Wang, Yugang Zhao

Frontiers in Heat and Mass Transfer, Vol.22, No.4, pp. 1087-1105, 2024, DOI:10.32604/fhmt.2024.053851

Abstract The exploration of performance and prediction of environmentally friendly refrigerant physical properties represents a critical endeavor. Equilibrium molecular dynamics simulations were employed to investigate the density and transport properties of propane and ethane at ultra-low temperatures under evaporative pressure conditions. The results of the density simulation of the evaporation conditions of the blends proved the validity of the simulation method. Under identical temperature and pressure conditions, increasing the proportion of R170 in the refrigerant blends leads to a density decrease while the temperature range in which the gas-liquid phase transition occurs is lower. The analysis More >

Amal El Berry, Marwa M. Ibrahim^*, A. A. Elfeky, Mohamed F. Nasr

Frontiers in Heat and Mass Transfer, Vol.22, No.4, pp. 1189-1207, 2024, DOI:10.32604/fhmt.2024.050684

Abstract A photovoltaic (PV) inverter is a vital component of a photovoltaic (PV) solar system. Photovoltaic (PV) inverter failure can mean a solar system that is no longer functioning. When electronic devices such as photovoltaic (PV) inverter devices are subjected to vapor condensation, a risk could occur. Given the amount of moisture in the air, saturation occurs when the temperature drops to the dew point, and condensation may form on surfaces. Numerical simulation with “COMSOL Software” is important for obtaining knowledge relevant to preventing condensation by using two steps. At first, the assumption was that the… More >

SHAN JIANG^1,2, XIUFENG LIN², YANFEI CHEN³, XINNING LI³, JIALI KANG^1,4,*

BIOCELL, Vol.48, No.8, pp. 1265-1273, 2024, DOI:10.32604/biocell.2024.051478

Abstract Background: Despite improvements in objective response rates to cisplatin-based combination chemotherapy, the majority of advanced ovarian cancer remains suboptimal, resulting in poor survival. it has been found that non-coding RNAs (ncRNAs) not only participate in the transmission of signals between various cells but also participate in tumor immunity and anti-tumor immune responses, thereby regulating tumor occurrence and development. However, the function and detailed mechanism of ultraconserved RNA (ucRNA) in ovarian cancer chemoresistance is still unclear. Methods: Western blotting assay, Quantitative real-time PCR analysis (qPCR), and Kaplan-Meier Plotter analysis were performed to analyze the expression and prognosis… More >

Shoukai Lin^1,3,4,*, Yifan Xiong², Shichang Xu^1,2, Manegdebwaoaga Arthur Fabrice Kabore², Fan Lin⁵, Fuxiang Qiu^1,2,*

Phyton-International Journal of Experimental Botany, Vol.93, No.7, pp. 1485-1502, 2024, DOI:10.32604/phyton.2024.050990

Abstract The SWEET (sugar will eventually be exported transporter) family proteins are a recently identified class of sugar transporters that are essential for various physiological processes. Although the functions of the SWEET proteins have been identified in a number of species, to date, there have been no reports of the functions of the SWEET genes in woodland strawberries (Fragaria vesca). In this study, we identified 15 genes that were highly homologous to the A. thaliana AtSWEET genes and designated them as FvSWEET1–FvSWEET15. We then conducted a structural and evolutionary analysis of these 15 FvSWEET genes. The phylogenetic analysis enabled us… More >

Yun Ren^1,*, Lianzheng Zhao², Xiaofan Mo², Shuihua Zheng², Youdong Yang¹

FDMP-Fluid Dynamics & Materials Processing, Vol.20, No.7, pp. 1593-1609, 2024, DOI:10.32604/fdmp.2024.046274

Abstract A coupled Computational Fluid Dynamics-Discrete Element Method (CFD-DEM) approach is used to calculate the interaction of a flexible rag transported by a fluid current with a fixed solid cylinder. More specifically a hybrid Eulerian-Lagrangian approach is used with the rag being modeled as a set of interconnected particles. The influence of various parameters is considered, namely the inlet velocity (1.5, 2.0, and 2.5 m/s, respectively), the angle formed by the initially straight rag with the flow direction (45°, 60° and 90°, respectively), and the inlet position (90, 100, and 110 mm, respectively). The results show More > Graphic Abstract

Muhammad Saleem¹, Jianhua Zhang¹, Muhammad Qasim², Rashid Iqbal³, Li Song^1,*

Phyton-International Journal of Experimental Botany, Vol.93, No.6, pp. 1325-1344, 2024, DOI:10.32604/phyton.2024.048493

Abstract Variations in the nutrients and water that plants require for metabolism, development, and the maintenance of cellular homeostasis are the main causes of abiotic stress in plants. It has, however, hardly ever been studied how these transporter proteins, such as aquaporin which is responsible for food and water intake in cell plasma membranes, interact with one another. This review aims to explore the interactions between nutrient transporters and aquaporins during water and nutrient uptake. It also investigates how symbiotic relationships influence the plant genome’s responses to regulatory processes such as photoperiodism, senescence, and nitrogen fixation. More >