Lai Yee Leung^*, Pamela J. VandeVord^∗,†, Alessandra Leonardi Dal Cengio^*, Cynthia Bir^*, King H. Yang^*, Albert I. King^*

Molecular & Cellular Biomechanics, Vol.5, No.3, pp. 155-168, 2008, DOI:10.3970/mcb.2008.005.155

Abstract Historically, blast overpressure is known to affect primarily gas-containing organs such as the lung and ear. More recent interests focus on its ability to cause damage to solid organs such as the brain, resulting in neurological disorders. Returning veterans exposed to blast but without external injuries are being diagnosed with mild traumatic brain injury (Warden 2006) and with cortical dysfunction (Cernak et al 1999). Decades of studies have been conducted to elucidate the effects of primary blast wave on the central nervous system. These studies were mostly concerned with systemic effects (Saljo et al 2000-2003; Kaur et al 1995-1997, 1999;… More >

Xudong Liu¹, Yunhan Cai¹, Bing Jia², Shengzhang Wang^1,*, Guanghong Ding¹

CMES-Computer Modeling in Engineering & Sciences, Vol.116, No.2, pp. 215-228, 2018, DOI: 10.31614/cmes.2018.04158

Abstract Our study evaluated the hemodynamic performance of an axial flow blood pump surgically implanted in idealized total cavopulmonary connection (TCPC) models. This blood pump was designed to augment pressure from the inferior vena cava (IVC) to the pulmonary circulation. Two Fontan procedures with single and bilateral superior vena cava (SVC) were compared to fit the mechanical supported TCPC physiologies. Computational fluid dynamics (CFD) analyses of two Pump-TCPC models were performed in the analyses. Pressure-flow characteristics, energy efficiency, fluid streamlines, hemolysis and thrombosis analyses were implemented. Numerical simulations indicate that the pump produces pressure generations of 1 mm to 24 mm… More >