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    ABSTRACT

    Effect of Ultrafine Nano-Zinc Particles on Cardiac Structure and Function in Myocardial Infarction Rabbits

    Pei Niu1, Li Li1, Yufan Huang2, Yunlong Huo3,*

    Molecular & Cellular Biomechanics, Vol.16, Suppl.1, pp. 45-45, 2019, DOI:10.32604/mcb.2019.05724

    Abstract Due to ultrafine Nano-zinc particles are major component of PM0.1, so we aimed to investigate how ultrafine Nano-zinc particles effect on cardiac structure and function in myocardial infarction (MI) rabbits. We chose twenty-four New Zealand rabbits who were divided into sham group, MI group and MI exposure group randomly, 8 rabbits in each group. We preformed LAD ligation operation in MI group and MI exposure group. After two weeks rabbits suffered from MI successfully, we put the MI exposure group into ventilation chamber filled with 500 ug/m3 ultrafine Nano-zinc particles for 6 hours per day. Sham group and MI group… More >

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